3-CYANO-5-METHYL-2-(2-NITROANILINO)THIOPHENE

3 - CYANO - 5 - METHYL - 2 - (2 - NITROANILINO) THIOPHENE, or 3 - cyano - 5 - methyl - 2 - (2 - nitroanilino) thiophene, is widely used.
In the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Drug developers can create compounds with unique pharmacological activities through subtle modification and transformation of their chemical structures, such as anti-cancer drugs and antibacterial agents that exhibit high affinity and selectivity for specific disease targets. Due to the special structure of thiophene with cyano and nitroaniline groups, the compound has the potential to combine with key targets in vivo, and then precisely regulate disease-related physiological processes.
In the field of materials science, 3-cyano-5-methyl-2 - (2-nitroanilino) thiophene is also of extraordinary value. Because of its structure containing electron-rich thiophene rings and cyano and nitro groups with electron-absorbing properties, it exhibits unique electrical and optical properties. It can be used to prepare organic semiconductor materials for frontier optoelectronic devices such as organic Light Emitting Diode (OLED) and organic field effect transistor (OFET). In such devices, the compound can effectively transport charge and generate luminescence, improving the luminous efficiency, stability and service life of the device.
In addition, in the field of pesticide chemistry, this compound may become an important starting material for the development of high-efficiency and low-toxicity new pesticides. With the optimization of its structure, it is expected to create pesticide varieties with high toxic activity against pests and friendly to the environment and non-target organisms, providing strong support for green prevention and control of agricultural pests.

3 - CYANO - 5 - METHYL - 2 - (2 - NITROANILINO) THIOPHENE is an organic compound with unique physical properties. The appearance of this compound is often solid, or crystalline, or powdered, depending on the preparation method and conditions.
Looking at its color, it is usually light yellow to light brown. Because its molecular structure contains a conjugated system, it presents this specific color. The conjugated system can absorb light of a specific wavelength, causing it to absorb in the visible region, and then exhibit the corresponding color.
The melting point is discussed, and it has a specific value due to factors such as intermolecular forces, hydrogen bonds, and the accumulation of aromatic rings. The interaction between groups such as cyano, nitro and sulfur heterocycles enhances the attractive force between molecules, and the melting point is relatively high. The exact melting point needs to be determined experimentally, but it is generally within the melting point range of common organic solids.
Its solubility is also worthy of attention. In organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc., there is a certain solubility. Because these solvents can form van der Waals forces or weak interactions with the molecules of the compound, it helps it to disperse in the solvent. However, in water, the solubility is poor, because its molecular polarity does not match that of water, and there is a lack of groups that form strong hydrogen bonds with water.
In addition, the density of the compound is also one of its physical properties. Although the exact density value needs to be accurately determined experimentally, according to its molecular structure and constituent elements, it can be inferred that the density should be similar to that of common organic compounds containing heteroatoms such as sulfur and nitrogen. Its density is affected by the degree of molecular packing compactness, the type and number of atoms.
In summary, the physical properties of 3 - CYANO - 5 - METHYL - 2 - (2 - NITROANILINO) THIOPHENE are determined by its unique molecular structure. These properties are quite critical in the research and application of organic synthesis, materials science and other fields.

To prepare 3-cyano-5-methyl-2- (2-nitroanilinyl) thiophene, the following method can be followed.
First take 5-methyl-2-aminothiophene-3-formonitrile as the starting material, place it in the reaction kettle with an appropriate base, stir well, so that the system is in an alkaline environment. This base can be a common base such as potassium carbonate. In this alkaline environment, slowly add 2-nitrochlorobenzene dropwise, control the reaction temperature and dripping speed, and ensure the smooth progress of the reaction. The chlorine atom in 2-nitrochlorobenzene is highly active, and under alkaline conditions, it can undergo nucleophilic substitution reaction with the amino group of 5-methyl-2-aminothiophene-3-formonitrile.
During the reaction process, the reaction process needs to be closely monitored, and the means such as thin layer chromatography (TLC) can be used. After the reaction is completed, the reaction solution is cooled and neutralized with dilute acid. At this time, the excess base is neutralized, and the product is precipitated in the solution. Then filter, collect the filter cake, and wash the filter cake alternately with water and an organic solvent to remove impurities. The organic solvent can be selected from ethanol, ether, etc. After multiple washes, the crude product can be obtained.
The crude product needs to be further purified, often by recrystallization. Select a suitable solvent, which needs to have high solubility of the product at high temperature and low solubility at low temperature, such as the mixed solvent of N, N-dimethylformamide (DMF) and water. The crude product is placed in this mixed solvent, heated to complete dissolution, filtered hot to remove insoluble impurities, and the filtrate is slowly cooled. The product is crystallized, filtered again, collected crystals, and dried at low temperature to obtain pure 3-cyano-5-methyl-2 - (2-nitroanilino) thiophene. During the whole preparation process, factors such as temperature, reaction time, and the proportion of raw materials have a great influence on the yield and purity of the product, and fine regulation is required to obtain ideal results.

I have not heard the exact price of 3 - CYANO - 5 - METHYL - 2 - (2 - NITROANILINO) THIOPHENE in the market. However, to find its price range, it can be deduced from various ways.
Looking at this compound, it has the structure of cyano, methyl, nitroaniline group and thiophene ring, etc. The synthesis may require multiple steps, and the materials used are also exquisite, which all affect its price.
The first way to find the price is to visit the supplier of chemical raw materials. They often sell a variety of chemicals, or if they have this product, you can get real information by inquiring about their price. The price may change due to the purchase quantity, supply and demand. If the quantity is more expensive or cheap, the supply is also the same; if the supply is less and the demand is more, the price is higher.
Furthermore, chemical trading platforms can be checked. Such platforms collect a lot of supply and demand information, and the price list is relatively complete. Prices vary in different periods, so it is advisable to look at recent trading prices to obtain a more accurate price range.
Scientific research institutions or laboratories also use this compound. If linked to it, or know its purchase price. However, its purchase volume, channels and commerce are different, and the price is only a reference.
Although the price range has not been determined, according to the above method, 3 - CYANO - 5 - METHYL - 2 - (2 - NITROANILINO) THIOPHENE may be able to get the approximate price range in the market. When you carefully observe the market situation and compare it with many parties, you will get a good price.

3 - CYANO - 5 - METHYL - 2 - (2 - NITROANILINO) THIOPHENE, this is a special organic compound. Its storage conditions are crucial, related to its quality and stability.
According to ancient principles, this material needs to be stored in a dry and cool place. Due to humid gas, it is easy to cause the compound to absorb moisture, trigger chemical reactions, and damage its structure and properties. A cool place can avoid the harm of high temperature, which often increases the molecular activity of the compound, causing it to decompose or deteriorate.
Furthermore, this material should be sealed and stored. If exposed to air, the oxygen, carbon dioxide and other components in the air, or interact with the compound, cause oxidation or other adverse changes. Sealed devices, such as glass bottles or special sealed containers, can effectively block the intrusion of air.
In addition, the storage place should be away from fire sources and strong oxidants. This compound may be flammable and dangerous in case of fire; strong oxidants can also react violently with it, causing danger. When storing, it should be kept at a certain distance from the source of fire and strong oxidants, and corresponding protective measures should be taken.
It should also be noted that the storage place should be kept well ventilated. Although it needs to be sealed, ventilation can prevent the accumulation of harmful gases due to possible minor leaks and ensure environmental safety. The stored compounds should also be checked regularly to see if their appearance and properties have changed. If there is any abnormality, they should be disposed of in time to ensure their quality and safety. In this way, it is necessary to properly store 3-CYANO-5-METHYL-2 - (2-NITROANILINO) THIOPHENE.