3-Chlorobenzothiophene-2-carboxylic acid hydrazide

3-Chlorobenzothiophene-2-carboxylic acid hydrazide, this is an organic compound. In terms of physical properties, it is mostly solid at room temperature. As for the specific melting point and boiling point, it needs to be accurately determined by experiments. Its chemical properties are unique because it is rich in specific functional groups in its structure.
Looking at its structure, it contains a benzothiophene ring substituted by an acyl hydrazide group (-CONHNH ²) and a chlorine atom. The acyl hydrazide group is highly active and can react with many reagents. For example, it can condensate with aldars and ketones to form hydrazone derivatives. This reaction is often used in the field of organic synthesis to construct new nitrogen-containing compounds and enrich the variety of compounds. And hydrazide can react with acid anhydride and acyl halide under appropriate conditions to form amide compounds, which is of great significance for the synthesis of amides with specific structures and functions.
Furthermore, although the chlorine atom on the benzothiophene ring is relatively stable, under specific nucleophilic substitution reaction conditions, the chlorine atom can be replaced by other nucleophilic reagents to realize the functional group transformation on the benzothiophene ring, providing the possibility for the synthesis of benzothiophene derivatives with more complex and diverse structures. However, such reactions usually require specific catalysts and suitable reaction conditions to ensure the smooth progress of the reaction and improve the yield and purity of the product. This compound is widely used in the field of organic synthetic chemistry, and may have potential application value in many fields such as medicinal chemistry and materials science. It can be used as a key intermediate to participate in the synthesis of various complex organic compounds.

3-Chlorobenzothiophene-2-carboxylic acid hydrazide, this substance has a wide range of uses. In the field of pharmaceutical research and development, it is often a key intermediate. Because of its specific chemical structure and activity, it can undergo various chemical reactions and couple with other compounds to build complex drug molecules, which have potential therapeutic effects against certain diseases.
In the field of materials science, it also has its uses. Or it can participate in the synthesis of specific materials, giving materials such as unique optical and electrical properties, or improving material stability and mechanical properties, providing the possibility for the development of new functional materials.
In the field of agricultural chemistry, it can be used as a raw material to create new pesticides. After modification, it has targeted killing or inhibitory activity against specific pests or pathogens, adding a boost to agricultural pest control, and is relatively environmentally friendly, meeting the needs of the current green agriculture development.
In the field of organic synthetic chemistry, it is an important starting material for the synthesis of various complex organic compounds. By enriching organic synthesis methods, a series of compounds with different structures are derived, expanding the research boundary of organic chemistry, and contributing to the progress of organic synthetic chemistry.

The synthesis of 3-chlorobenzothiophene-2-carboxylic acid hydrazide is an important problem in organic synthesis. There are many methods, the common ones are starting with 3-chlorobenzothiophene-2-carboxylic acid and going through the step of acylation. First, 3-chlorobenzothiophene-2-carboxylic acid is co-placed in a suitable reaction bottle with thionyl chloride or oxalyl chloride, and an appropriate amount of catalyst, such as N, N-dimethylformamide, is heated to a moderate temperature, usually at 50-80 degrees Celsius. When the reaction number is, this is the method of obtaining 3-chlorobenzothiophene-2-carbonyl chloride.
The second time makes the prepared 3-chlorobenzothiophene-2-carbonyl chloride react with hydrazine hydrate. 3-Chlorobenzothiophene-2-carbonyl chloride is dissolved in a suitable organic solvent, such as dichloromethane or tetrahydrofuran, slowly added to a solution containing an appropriate amount of hydrazine hydrate, the temperature is controlled at 0-10 degrees Celsius, and then raised to room temperature for a few hours. After the reaction is completed, the pure 3-chlorobenzothiophene-2-carboxylic acid hydrazide can be obtained by conventional separation and purification methods, such as extraction, column chromatography, etc.
There is another method, or the parent body of benzothiophene is modified first, chlorine atoms and carboxyl groups are introduced, and then a series of reactions are carried out to form hydrazide. However, all these methods need to carefully control the reaction conditions, consider factors such as raw material purity, reaction temperature, time and reagent dosage, so that the reaction goes smoothly and the yield and purity of the product are improved. In this way, the essence of the synthesis of 3-chlorobenzothiophene-2-carboxylic acid hydrazide lies.

I think this "3 - Chlorobenzothiophene - 2 - carboxylic acid hydrazide" is a chemical substance. However, its market price is difficult to determine. Due to many reasons intertwined, its price is influenced.
First, the price of raw materials has a great impact. If the raw materials required for the preparation of this compound are not easy to obtain, or the origin is changed and the supply is reduced, the price will rise. On the contrary, if the raw materials are abundant, the price will stabilize or drop.
Second, the production process is complicated and simple, which is related to cost. If the process is complicated, high-end equipment, fine operation are required, and strict craftsman skills are required, the cost of production will be high, and the price will also rise. If the process is simple, the cost can be reduced, and the price can also be reduced.
Third, the market supply and demand situation is the key. If the demand for this compound in the fields of medicine, materials and other fields increases sharply, and the supply is difficult to keep up in time, the price will soar. If the demand is low, merchants will destock or reduce prices in order to sell.
Fourth, the current situation is turbulent and policy changes will also be affected. Such as trade friction, which restricts import and export and increases costs; or tightening environmental protection policies and restricting production, all make prices fluctuate.
In the past, "Tiangong Kaiwu" recorded various process products, but at that time, the chemistry was not as developed as it is today, and there were no such fine compounds. At present, the price of "3 - Chlorobenzothiophene - 2 - carboxylic acid hydrazide" needs to check the chemical market information in real time, consult the industry experts, and refer to the data of the trading platform to obtain a relatively accurate number. It is difficult to hide the exact price geometry.

3-Chlorobenzothiophene-2-carboxylic acid hydrazide is a fine chemical. Many things must be paid attention to during storage and transportation.
First storage environment. This product should be placed in a cool, dry and well-ventilated place. Avoid open flames and hot topics, because if it is heated, it may cause decomposition and damage its quality. And humidity is also critical, the environment is too humid, or 3-chlorobenzothiophene-2-carboxylic acid hydrazide is damp, causing chemical reactions and reducing its purity.
Times and packaging materials. Be sure to choose sealed, corrosion-resistant packaging. It is advisable to use glass bottles or iron drums lined with plastic bags to prevent them from contacting with outside air and moisture and ensure their stability.
Furthermore, storage needs to be classified. Do not mix with oxidants, acids, alkalis, etc., and cause violent chemical reactions with them, resulting in dangerous accidents.
When transporting, do not slack off. Make sure that the container is free of leakage, and is protected from sun, rain and high temperature on the way. Handling should be light and light, and packaging damage should be avoided.
In short, proper storage and transportation of 3-chlorobenzothiophene-2-carboxylic acid hydrazide is related to its quality and safety. Adhere to the above precautions to avoid accidents and ensure that its performance is not damaged.