3-CHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID

3-Chloro-1-benzothiophene-2-carboxylic acid, this is an organic compound with unique chemical properties. Its appearance is often solid, the color is white to pale yellow powder, and it can remain stable under certain conditions.
When it comes to physical properties, the melting point and boiling point of this compound are of great significance for its identification and purification. Its melting point is about a certain range (the specific value needs to be accurately determined by experiments). This characteristic helps to identify the purity of the compound in the laboratory with the help of melting point testers and other tools. If the purity is high, the melting point range is narrow and close to the theoretical value; conversely, if there are many impurities, the melting point will be reduced and the range will be wider. The data related to the boiling point is also critical, and the boiling point under a specific pressure is also an important indicator of the substance, which can be used for separation and purification.
In terms of chemical properties, because its structure contains carboxyl groups and chlorine atoms, it exhibits the typical chemical activity of two types of groups. The carboxyl group is acidic and can neutralize with the base to form the corresponding carboxylate and water. For example, when reacted with sodium hydroxide solution, 3-chloro-1-benzothiophene-2-carboxylate can be formed with water. This reaction can be used in organic synthesis to prepare derivatives of the compound, or to improve its solubility in water through salt formation.
The chlorine atom introduces nucleophilic substitution activity for the compound. Under suitable conditions for nucleophilic reagents and reactions, chlorine atoms can be replaced by nucleophilic reagents to form new organic compounds. If there are specific solvents and catalysts, they can be replaced with nucleophilic reagents such as alcohols and amines, providing the possibility for the construction of complex organic molecular structures.
In addition, the benzothiophene ring structure of the compound endows it with certain aromatics, making it capable of aromatic electrophilic substitution reactions under specific conditions, such as halogenation, nitrification, sulfonation, etc., further expanding its application space in the field of organic synthesis.

3-Chloro-1-benzothiophene-2-carboxylic acid, this substance is in the state of white to off-white crystalline powder. Its melting point is quite high, about 182-186 ° C, which is of great significance for discrimination and purification.
When it comes to solubility, it shows different properties in common organic solvents. In alcoholic solvents such as methanol and ethanol, it has a certain solubility, but the solubility is not very high. In water, its solubility is very small. Because of its molecular structure, although carboxyl groups can form hydrogen bonds with water, the presence of benzothiophene rings and chlorine atoms increases the hydrophobicity of the molecule, so it is difficult to dissolve in water.
In terms of stability, under normal environmental conditions, if stored in a cool place away from light, it can remain relatively stable. When encountering strong acids and bases, its structure will be affected. The carboxyl group can neutralize with the base, while the chlorine atom on the benzothiophene ring may undergo substitution and other reactions under strong base conditions, resulting in structural changes. And this substance also has a certain sensitivity to light. Long-term light exposure may trigger photochemical reactions such as intramolecular electron transitions, which affect its purity and properties.

3-Chloro-1-benzothiophene-2-carboxylic acid, this is an organic compound. Looking at its properties and characteristics, it has applications in many fields.
In the field of pharmaceutical research and development, organic compounds are often key raw materials. 3-Chloro-1-benzothiophene-2-carboxylic acid can be used as an intermediate for the synthesis of specific drugs. Due to its unique chemical structure, it may be able to participate in the construction of molecular structures with specific pharmacological activities. Take the development of a certain type of anti-cancer drug as an example, or take the specific reaction of this compound to introduce the required chemical groups to shape drug molecules that fit the target of cancer cells and help solve the cancer problem. < Br >
In the field of materials science, it also has potential value. Organic carboxylic acid compounds may be used to prepare special polymer materials. 3-Chloro-1-benzothiophene-2-carboxylic acid can be used as a functional monomer to polymerize with other compounds, giving unique properties to the material. For example, the preparation of materials with special optical and electrical properties can be used in optoelectronic devices, such as organic Light Emitting Diode (OLED), to improve device performance and efficiency.
In the field of agricultural chemistry, or can participate in the creation of pesticides. Some organic sulfur compounds have inhibitory effects on crop diseases and insect pests. This compound may be chemically modified to develop high-efficiency, low-toxicity and environmentally friendly pesticides that protect the thriving growth of crops and ensure food yield and quality.
In summary, 3-chloro-1-benzothiophene-2-carboxylic acid has shown application potential in the fields of medicine, materials and agricultural chemistry, providing new opportunities and directions for the development of various fields.

The synthesis of 3-chloro-1-benzothiophene-2-carboxylic acid is an important topic in the field of organic synthesis. The synthesis path is diverse, and the selection method needs to consider many factors such as the availability of raw materials, the difficulty of reaction conditions and the high and low yield.
One of the common synthesis methods is to use benzothiophene as the starting material. First, under suitable reaction conditions, benzothiophene reacts with chlorine reagents, and chlorine atoms are introduced at the third position of benzothiophene to obtain 3-chlorobenzothiophene. In this step, the reaction temperature, time and the dosage of reagents need to be carefully adjusted to ensure the reaction selectivity.
Then, 3-chlorobenzothiophene is reacted with a carboxylating reagent. The carboxylation method can be a classic organometallic reagent method, such as the Grignard reagent method. React 3-chlorobenzothiophene with magnesium to form a Grignard reagent, then react with carbon dioxide, and then acidify to obtain 3-chloro-1-benzothiophene-2-carboxylic acid. In this process, the preparation of Grignard reagents needs to be carried out under severe conditions without water and oxygen to prevent side reactions with water and oxygen.
Another synthesis strategy is to use carboxyl-containing benzothiophene derivatives as starting materials, and introduce chlorine atoms at 3 positions through a specific reaction. For example, 1-benzothiophene-2-carboxylic acid can be prepared first, and then chlorine atoms are introduced at 3 positions by selective chlorination reaction. This chlorination reaction requires the selection of suitable chlorination reagents and catalysts to ensure that the chlorination reaction occurs precisely at 3 positions.
There are also other compounds containing sulfur and benzene rings as starting materials, and benzothiophene rings are constructed through multi-step reactions and chlorine atoms and carboxyl groups are introduced. Although there are many steps in this path, it is also a feasible method in some specific situations due to the special advantages of raw materials or the special requirements for product purity.
In short, the synthesis of 3-chloro-1-benzothiophene-2-carboxylic acid has its own advantages and disadvantages. It is necessary to weigh the advantages and disadvantages according to actual needs and carefully choose the best synthesis path.

What you are inquiring about is the market price of 3-chloro-1-benzothiophene-2-carboxylic acid. However, the price of this product often changes for many reasons, and it is difficult to determine it suddenly.
The fluctuation of its price is mainly related to the raw material. If the raw materials required for the manufacture of this acid, such as specific sulfur, chlorine and other compounds, are abundant and affordable, the cost of 3-chloro-1-benzothiophene-2-carboxylic acid is also low, and its market price can be reduced. On the contrary, if raw materials are scarce, the price will be high, and the price of finished products will also rise.
Furthermore, the quality of the production process also affects the price. Advanced and efficient processes can reduce consumption and improve quality, reduce production costs, and the market price may be more accessible to the people. If the process is outdated, the cost is high and the output is low, the price may not be reduced.
The market supply and demand relationship is a key factor. If the demand for this acid is strong and the output is limited, the merchant will raise the price in pursuit of profit. However, if the supply exceeds the demand, the price will fall for promotional goods.
In addition, the difference in regions also makes the price different. In places where the chemical industry is concentrated and the logistics is convenient, the cost is lower, and the price may be slightly lower. In remote places, the transportation cost is high, and the price may be relatively high. < Br >
If you want to know the exact market price, you should carefully investigate the market conditions of chemical raw materials, visit relevant chemical product trading platforms, and consult professional chemical distributors or manufacturers in order to obtain a more accurate price.