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What is the chemical structure of 3- (carboxymethoxy) -2-thiophenecarboxylic acid?
3 - (carboxymethoxy) -2 -thiophene carboxylic acid, its chemical structure can be deduced as follows.
This compound contains a thiophene ring. The thiophene is a five-membered heterocycle, composed of four carbon atoms and one sulfur atom, and is aromatic. The 2-position of the thiophene ring is connected with a carboxyl group, that is, a -COOH group. The 3-position connected (carboxymethoxy) can be dissected as a methoxy-OCH -2 - at one end is connected to the 3-position of the thiophene ring, and the methylene-CH -2 - at the other end is reconnected to the carboxyl-COOH.
To express its structure in ancient Chinese, it is said: There is a heterocyclic name thiophene, the ring has five atoms, and the four-carbon-one-sulfur phase is the title. In the second position of the ring, it is connected to the genus of carboxyl group, which is in the shape of -COOH. The three digits of the ring are connected to the group, which is first methoxy, first in the shape of -OCH ² -, and its methylene and carboxyl groups are continued to form the state of -CH ² COOH. In this way, the structure of 3 - (carboxymethoxy) -2 -thiophene carboxylic acid is clear.
What are the main uses of 3- (carboxymethoxy) -2-thiophenecarboxylic acid?
3- (carboxymethoxy) -2 -thiophenecarboxylic acid, this is an organic compound. It has a wide range of uses and can be used as a key intermediate in the synthesis of many drugs in the field of medicine. The existence of specific structures such as the thiophene ring and carboxyl group endows it with unique chemical and biological activities, which can participate in the construction of drug molecules, and then affect the efficacy and stability of drugs. For example, it can be used to synthesize drugs with antibacterial and anti-inflammatory effects.
In the field of materials science, this compound also has its uses. With its carboxyl group reactivity, it can participate in the synthesis of polymers, thereby preparing polymer materials with specific properties. For example, polymers with good solubility, thermal stability or mechanical properties can be obtained by polymerization with other monomers, or can be applied to the improvement of coatings, plastics and other materials.
In the field of organic synthesis, as an important organic synthesis intermediate, it can be converted into other more complex organic compounds through a series of chemical reactions. Due to the fact that different functional groups in its structure can undergo reactions such as esterification, amidation, and substitution, it provides a rich reaction path for organic synthesis chemists to construct various organic molecules with special structures and functions, contributing to the development of organic synthesis chemistry.
What are the synthesis methods of 3- (carboxymethoxy) -2-thiophenecarboxylic acid?
To prepare 3- (carboxymethoxy) -2 -thiophenecarboxylic acid, there are various methods. It can be obtained from thiophene and obtained through several steps.
First, thiophene and a suitable reagent are reacted under specific conditions to introduce the desired group into the thiophene ring. For example, thiophene can be reacted with a halogenated reagent in a suitable solvent with the help of a catalyst to perform halogenation to obtain halogenated thiophene.
Then, in the presence of a base, the halogenated thiophene and the reagent containing carboxymethoxy are reacted by nucleophilic substitution to connect the carboxymethoxy group to the appropriate position of the thiophene ring. In this process, the properties of the solvent, the strength and dosage of the base, and the temperature and duration of the reaction all need to be considered in detail.
Or, other methods can be found. If a compound with a similar structure is used as a raw material, the functional group is converted and modified. First protect the specific functional group of the raw material, and then react, and then protect the group to gradually build the structure of the target molecule.
There are also methods of biosynthesis. By the action of microorganisms or enzymes, under mild conditions, the substrate is catalyzed to generate products. However, this approach requires a deep understanding of the biological system, and the screening and culture of biocatalysts is crucial. In the process of
preparation, detailed monitoring of each step of the reaction is required to ensure the purity and yield of the product. Thin-layer chromatography, gas chromatography, liquid chromatography and other methods can be used to observe the process of the reaction and determine the content of the product. After multi-method exploration and optimization, 3 - (carboxymethoxy) -2 -thiophenecarboxylic acid can be obtained.
What are the physical properties of 3- (carboxymethoxy) -2-thiophenecarboxylic acid?
3- (carboxymethoxy) -2 -thiophenecarboxylic acid, this material has unique properties, let me explain in detail. It is a white to light yellow crystalline powder, which looks like fine sand and has a fine texture.
In terms of solubility, it is slightly soluble in water, but it can show better solubility in organic solvents such as ethanol and acetone. The melting point of this substance is quite high, about 160-165 ° C. When heated to this temperature range, it gradually converts from a solid state to a liquid state, like melting ice and snow. This property is quite characteristic among many organic compounds.
Furthermore, its stability is also worth mentioning. Under normal temperature and pressure and dry environment, it can remain stable for a long time and is not easy to react with surrounding substances. However, if it encounters strong acid and alkali, it will be a big enemy, and its chemical structure will change, and its properties will also change.
From the perspective of chemical structure, this compound contains thiophene ring and carboxyl group, carboxymethoxy group and other functional groups. The presence of thiophene ring endows it with certain aromatic properties, which makes it exhibit unique activity in chemical reactions. Carboxyl group and carboxymethoxy group give it acidic properties, which can neutralize and react with alkali to form corresponding salts. This structural property makes it widely used in the field of organic synthesis, such as as as an intermediate, participating in the synthesis process of many drugs and pesticides, just like building the foundation of a high-rise building.
What is the price range of 3- (carboxymethoxy) -2-thiophenecarboxylic acid in the market?
I don't know the price range of "3 - %28carboxymethoxy%29 - 2 - thiophenecarboxylic acid" on the market. This name is a chemical term, and it must be a special chemical substance. The price of chemicals on the market often varies depending on quality, purity, supply and demand, and manufacturers. If you want the price, you can go to the chemical trading platform, supplier website for details, or consult the chemical reagent dealer to get a more accurate price range. I regret that it is difficult for me to tell the price directly today. I hope you will follow this path to find it.