3 Bromo 2 Chlorothiophene
quinoline thiophene imidazole thiazole

3-Bromo-2-chlorothiophene

Taiy Chemical

    Specifications

    HS Code

    598458

    Chemical Formula C4H2BrClS
    Molar Mass 199.48 g/mol
    Appearance Liquid (usually)
    Boiling Point Data varies, around 180 - 190 °C
    Density Data may vary, typically in the range of halogenated thiophenes
    Solubility In Water Insoluble (non - polar compound)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Vapor Pressure Low, as it is a relatively high - boiling liquid

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    General Information
    Where to Buy 3-Bromo-2-chlorothiophene in China?
    As a trusted 3-Bromo-2-chlorothiophene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-Bromo-2-chlorothiophene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 3-bromo-2-chlorothiophene?
    3-Bromo-2-chlorobenzoic acid is an organic compound with unique chemical properties.
    This substance is white to light yellow crystalline powder and is quite stable at room temperature and pressure. From the perspective of chemical activity, the carboxyl group (-COOH) is acidic and can neutralize with the base to form the corresponding carboxylate and water. For example, when reacted with sodium hydroxide, 3-bromo-2-chlorobenzoic acid and water are formed.
    The bromine atom (-Br) and the chlorine atom (-Cl) act as halogen atoms, giving the compound halogenated hydrocarbon properties. They can participate in nucleophilic substitution reactions. When they meet nucleophilic reagents such as sodium alcohol and ammonia, halogen atoms can be replaced by nucleophilic reagents to form new compounds. For example, when reacting with sodium ethanol, bromine atoms or chlorine atoms may be replaced by ethoxy groups (-OCH ² CH 😉) to form new organic compounds containing ethoxy groups.
    In addition, the benzene ring structure makes 3-bromo-2-chlorobenzoic acid aromatic, and electrophilic substitution reactions on benzene rings such as halogenation, nitrification, and sulfonation can be carried out. Under appropriate catalyst and reaction conditions, new substituents can be introduced at other positions on the benzene ring.
    However, the chemical properties of this compound are affected by the position of the substituent and electronic effects. Bromine and chlorine are electron-withdrawing groups, which will reduce the electron cloud density of the benzene ring, slightly reduce the activity of electrophilic substitution, and the reaction mainly occurs in the meta (relative to the carboxyl group). The carboxyl group is also an electron-withdrawing group, which also affects the distribution of the benzene ring electron cloud, further affecting the reactivity and selectivity.
    What are the main uses of 3-bromo-2-chlorothiophene?
    The main uses of 3-2-fluoric acid are generally as follows:
    First, in the field of metallurgy, it can be used as a melting aid. For example, in the field of metallurgy and other metals, 3-2-fluoric acid can reduce the melting of stone, promote its melting, and can remove the gold contained in the gold, improve the gold, so that the obtained gold is more efficient, better quality.
    Second, in the process of chemical production, its important raw materials can be used for many synthesis reactions, such as the formation of fluorine-containing compounds. This compound has a wide range of uses in manufacturing, materials, plastics, etc. Like the synthesis of some special effects, 3-2-fluoric acid can play an important role in helping to generate specific molecules.
    Third, in the glass processing, 3-2-fluoric acid is also indispensable. Because of its ability to react to the silica in the glass, it can be used for engraving glass. In this way, exquisite flowers, patterns, or frosting of the glass can be created on the glass surface to increase the performance and usability of the glass, such as the processing of various glass products.
    Fourth, in the manufacturing process, it can be used for cleaning and engraving semi-finished materials. In the integrated manufacturing process, it is necessary to perform the finishing process of the semi-wafer. 3-2-fluoric acid can remove oxides and layers on the wafer surface, ensuring the performance and manufacturing accuracy of the wafer, and providing protection for the production of high-end products.
    What is the synthesis method of 3-bromo-2-chlorothiophene?
    To make cyanoarsine chloride, the method is as follows:
    Prepare all kinds of medicinal utensils first. There are several kinds of cyanides required, and those with good purity are also prepared with chlorine-containing agents, such as a certain chloride, and their purity is also required. For utensils, choose a sturdy and durable container, preferably glass or special pottery, so that it is well sealed to prevent the escape of poisonous gases.
    When making, first put an appropriate amount of cyanide in the container, and the action should be slow and careful, so as not to make mistakes. Then, according to a certain proportion, slowly add the chlorine-containing agent. This process requires strict observation of temperature changes, and temperature control by water bath or other methods, so that the reaction can be carried out at a suitable heat. If the temperature is too high and the reaction is too fast, it may cause danger; if it is too low, the reaction will be slow and affect the effect.
    During the reaction, it can be seen that there are strange changes in the container, or color changes, or bubbles escape. At this time, you must concentrate, stay by the side, and fine-tune according to the reaction. Wait for the reaction to gradually stabilize and last for a period of time to fully combine.
    However, this compound, tricyanodichloronsine, is extremely toxic, and the time protection must not be sparse. The manufacturer must wear special protective clothing and an airtight mask in a well-ventilated place. After it is made, it is also properly stored to prevent leakage and endanger humans and animals.
    Although this is a synthetic method, it is not for legitimate use due to its highly toxic properties. Do not try it easily to avoid major disasters.
    What should I pay attention to when storing and transporting 3-bromo-2-chlorothiophene?
    3-%-2-oxygen is required for storage and storage, so pay attention to the following:
    The first heavy container is taken. Because 3-% is corrosive, 2-oxygen is also corrosive, and both can invade multiple materials. Therefore, it is advisable to use containers that can withstand its corrosion, such as corrosion-resistant plastic materials and glass materials (glass stoppers need to be avoided for oxygen). If the quality of the glass is not good, it will also suffer from slow corrosion of oxygen, causing the bottle mouth to adhere.
    Secondly, the preservation environment is of paramount importance. It is important to store in a dry place, and it is a good source of fire and gas. In case of high temperature, 3-% may accelerate the speed and cause harmful damage. 2-Oxygen absorption is low, and the tide environment is easy to cause deliquescence. And both need to be separated from flammable and explosive materials to prevent accidents.
    Furthermore, the process should not be ignored. It is necessary to properly pack according to the relative method, and to identify dangerous products. The tools need to be cleaned and dry, and must not be mixed with other incompatible materials. Pay attention to shock-proof and anti-bumping on the way to avoid container rupture resulting in 3-% or 2-% oxygen leakage.
    The most important, whether it is not stored or not, must be placed in the safety management system. Managers need to be well-versed in the characteristics and emergency management methods of both. Equipped with phase prevention equipment and emergency treatment, in the event of accidents such as leakage, it can quickly and positively reduce harm.
    What are the effects of 3-bromo-2-chlorothiophene on the environment and human health?
    3-Bromo-2-chlorotoluene, its impact on the environment and human health cannot be ignored.
    If this substance escapes in the environment, it may cause many disturbances to the ecosystem. In terms of aquatic ecology, it may be toxic and can harm aquatic organisms, causing the survival and reproduction of fish, shellfish, etc. If it persists in the soil, it may affect the activity of soil microorganisms, which in turn interferes with the normal ecological functions of the soil, such as nutrient cycling, decomposition of organic matter, etc. And it may be persistent in the environment, difficult to be rapidly degraded, or will exist in environmental media for a long time, and accumulate continuously.
    As for human health, its impact should not be underestimated. Inhalation through the respiratory tract or skin contact can invade the human body. It may irritate the respiratory tract, cause cough, asthma and other diseases, long-term exposure, or even cause lung diseases. For the skin, it may cause skin allergies, redness, swelling, itching and other discomfort. If ingested inadvertently, it will endanger the digestive system, causing nausea, vomiting, abdominal pain and other symptoms.
    In addition, due to its chemical properties, it may interfere with normal physiological and biochemical processes in the body, affecting the functions of the endocrine system, nervous system, etc. Such as affecting the transmission of neurotransmitters, disrupting the normal neuroregulation of the human body, causing dizziness, fatigue, memory loss and other phenomena. < Br >
    Therefore, the use and treatment of 3-bromo-2-chlorotoluene should be treated with caution and strict control and protection measures should be taken to reduce its harm to the environment and human health.