3 Acetamidothiophene 2 Carboxylic Acid
quinoline thiophene imidazole thiazole

3-acetamidothiophene-2-carboxylic acid

Taiy Chemical

    Specifications

    HS Code

    450568

    Name 3-acetamidothiophene-2-carboxylic acid
    Molecular Formula C7H7NO3S
    Molecular Weight 185.20
    Appearance Solid (predicted)
    Melting Point 210 - 212 °C (lit.)
    Solubility Soluble in DMSO, Methanol
    Pka 3.76±0.20 (Predicted)
    Logp 0.78 (Predicted)
    Density 1.442±0.06 g/cm3 (Predicted)
    Boiling Point 421.4±30.0 °C at 760 mmHg (Predicted)

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    General Information
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    Frequently Asked Questions

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    What is the chemistry of 3-acetamidothiophene-2-carboxylic acid?
    3-Acetaminothiophene-2-carboxylic acid, this is an organic compound. Its properties are common to acids, and it can combine with alkali phases to produce salts and water. It contains carboxyl groups, which can release hydrogen ions, causing it to be acidic.
    And because of its acetamino group, this group has a certain stability, but under certain conditions, it will also react. For example, under a suitable acid-base environment or catalyst action, the acetamino group may undergo hydrolysis, causing molecular structure changes.
    Furthermore, the thiophene ring provides it with a unique electron cloud distribution and aromaticity. This aromaticity makes the compound exhibit special activity and selectivity in some reactions. It may participate in the electrophilic substitution reaction, the electron cloud density distribution of the marginal thiophene ring, and the electrophilic reagent is prone to attack specific locations.
    And the physical properties of the compound are also considerable. Its solubility may vary due to the polar groups and non-polar parts in the molecule. The polarity of the carboxyl group makes the compound have a certain solubility in polar solvents, while the non-polar parts of the thiophene ring and the acetamide group affect its solubility. Physical constants such as melting point and boiling point are also determined by intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., which all play a role in it. < Br >
    Its chemical properties are complex and diverse, and it can be used as a key intermediate in the field of organic synthesis, leveraging its various reaction properties to construct more complex organic molecular structures.
    What are the main uses of 3-acetamidothiophene-2-carboxylic acid?
    3-Acetaminothiophene-2-carboxylic acid, this substance has a wide range of uses. In the field of medicine, it is often a key intermediate for the synthesis of many drugs. Due to its unique chemical structure, it can participate in the construction of molecular structures with specific pharmacological activities, help to develop new therapeutic drugs, or optimize the properties of existing drugs, and play an important role in disease prevention and treatment.
    In the field of materials science, it also shows potential value. With its special chemical properties, it can be integrated into the material synthesis process through specific reactions and treatments, giving materials novel properties, such as improving material stability, optical properties, etc., providing the possibility for the creation of new functional materials.
    In the field of organic synthesis, as an important building block for organic synthesis, it can react with a variety of reagents to realize the construction of complex organic compounds. With its chemical activity check point, various functional group transformations and connections can be carried out, providing an effective way for the synthesis of organic molecules with specific structures and functions, and promoting the development and innovation of organic synthesis chemistry.
    What are the synthetic methods of 3-acetamidothiophene-2-carboxylic acid?
    The synthesis methods of 3-acetaminothiophene-2-carboxylic acid have been investigated since ancient times. There are many methods, and they are described in detail today.
    First, thiophene is used as the starting material and prepared by multi-step reaction. First, the thiophene undergoes a specific substitution reaction, introduces the corresponding functional group, and then interacts with the acetylation reagent to form an acetaminostructure. Subsequently, through a specific carboxylation reaction, the carboxyl group is introduced at the 2 position of thiophene to finally obtain 3-acetaminothiophene-2-carboxylic acid. In this process, the control of the reaction conditions at each step is very critical, such as the reaction temperature, the proportion of reactants, the choice and amount of catalyst, etc., all of which have a great impact on the yield and purity of the product.
    Second, other sulfur-containing heterocyclic compounds are also used as starters. After appropriate functional group transformation and modification, the structure of the target molecule is gradually constructed. This approach may utilize some unique chemical reactions to achieve the purpose of efficient synthesis. However, it also faces many challenges, such as the difficulty of obtaining raw materials, the complexity of reaction steps, and the control of side reactions.
    Third, there is another method, which is based on some easily available organic compounds, by means of intermolecular condensation, cyclization and other reactions, the thiophene ring is constructed and the desired functional group is introduced. This strategy requires in-depth understanding of the reaction mechanism and precise regulation of the reaction process to improve the production efficiency of the product.
    Although there are many methods for synthesizing 3-acetaminothiophene-2-carboxylic acid, each has its own advantages and disadvantages. In practical application, when the appropriate synthesis path is carefully selected according to specific circumstances, such as the availability of raw materials, cost, and requirements for product purity, in order to achieve the best synthesis effect.
    What is the price range of 3-acetamidothiophene-2-carboxylic acid in the market?
    I don't know what the price range of 3 - acetamidothiophene - 2 - carboxylic acid is in the market. However, "Tiangong Kaiwu" focuses on the craftsmanship and agricultural production, but does not involve the price of this product. If you want to know the price today, you can consult the chemical raw material trading platform, chemical suppliers, or consult people in the chemical product sales industry. They often know the market conditions of various chemicals and can tell you the approximate price range of this chemical. Or the price varies due to purity, output, market supply and demand, etc. And the price may vary from place to place. You need to check the information of many parties to get a more accurate price.
    What are the storage conditions for 3-acetamidothiophene-2-carboxylic acid?
    3-Acetaminothiophene-2-carboxylic acid is a kind of organic compound. Its storage conditions are crucial, which is related to the stability and quality of this substance.
    According to ancient principles, this substance should be stored in a cool and dry place. A cool place can avoid the disturbance of high temperature, which can easily cause its molecules to be active, or cause decomposition and deterioration. A dry environment can avoid the harm of moisture, which is often the cause of many chemical reactions and can cause adverse changes such as hydrolysis of compounds.
    And it should be sealed and stored. Sealing can prevent air, oxygen or other gases in the air, or react with the compound, damaging its purity and properties. Furthermore, it is necessary to keep away from fire sources and strong oxidants. Fire sources can cause the risk of combustion, and strong oxidants are easy to react violently with 3-acetaminothiophene-2-carboxylic acid, endangering safety.
    In the choice of storage containers, it should not be ignored. Chemically stable containers, such as glass or specific plastic materials, should be used to prevent the container from interacting with compounds and affecting their quality. All of these are essential for the proper preservation of 3-acetaminothiophene-2-carboxylic acid. According to this, it can ensure its long-term stability.