3 4 Dihydroxy Thiophene 2 5 Dicarboxylic Acid Dimethyl Ester
quinoline thiophene imidazole thiazole

3,4-Dihydroxy-thiophene-2,5-dicarboxylic acid dimethyl ester

Taiy Chemical

    Specifications

    HS Code

    314850

    Chemical Formula C8H8O6S
    Molar Mass 232.21 g/mol
    Appearance Solid (usually white or off - white)
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Melting Point Typically has a defined melting point (data may vary, around 100 - 200°C approximately)
    Density Estimated density value based on similar compounds (approximate value)
    Pka Has acidic groups, pKa values for hydroxy groups can be in certain ranges (e.g., around 9 - 11 for phenolic - like hydroxy)
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    General Information
    Where to Buy 3,4-Dihydroxy-thiophene-2,5-dicarboxylic acid dimethyl ester in China?
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    Frequently Asked Questions

    As a leading 3,4-Dihydroxy-thiophene-2,5-dicarboxylic acid dimethyl ester supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4-Dihydroxy-thiophene-2, 5-dicarboxylic acid dimethyl ester
    3% 2C4-dihydroxy-thiophene-2% 2C5-dicarboxylic acid dimethyl ester, this is an organic compound. It has unique chemical properties.
    In terms of physical properties, it is mostly solid at room temperature, but its melting point and boiling point are unusual due to the intra-molecular structure. This compound contains a thiophene ring, which is connected with a dihydroxy group and a dimethyl dicarboxylate group. The thiophene ring is aromatic and gives specific stability to the compound.
    In terms of chemical activity, hydroxyl groups can participate in many reactions. First, it can esterify with acids to form new ester compounds. Because the oxygen atom in the hydroxyl group has a lone pair of electrons, the nucleophilicity is considerable, and it is easy to react with the carbonyl carbon of the acid. Second, the hydroxyl group can participate in the dehydration reaction, and under appropriate conditions, the intramolecular or intermolecular dehydration can form ethers or unsaturated compounds.
    In addition, the dimethyl dicarboxylate group also has important reactivity. The ester group can be hydrolyzed under basic conditions to form corresponding carboxylic salts and alcohols. This hydrolysis reaction is a common reaction of esters and has a wide range of uses in organic synthesis and analysis.
    In addition, the compound contains multiple polar groups and may have certain solubility in organic solvents. According to the principle of similar miscibility, a suitable solvent can be selected to dissolve and separate it. It can be used as a key intermediate in the field of organic synthesis. By modifying and transforming its groups, more complex and diverse organic molecular structures can be constructed, providing an important foundation for research in materials science, medicinal chemistry and many other fields.
    What are the main uses of 4-Dihydroxy-thiophene-2, 5-dicarboxylic acid dimethyl ester
    3% 2C4 - Dihydroxy - thiophene - 2% 2C5 - dicarboxylic acid dimethyl ester, that is, 3,4 - dihydroxythiophene - 2,5 - dimethyl diformate, is widely used.
    In the field of pharmaceutical chemistry, it is a key intermediate for the synthesis of many drugs. The subtlety of pharmaceutical chemistry lies in the subtle difference in molecular structure that can make a world of difference in pharmacological activity. The specific structure of this compound is just like the cornerstone of building a building block of delicate drug molecules. Using it as a starting material, through a series of delicate chemical reactions, drug molecules with unique physiological activities can be constructed, or they can act on specific biological targets, providing effective means for the treatment of diseases.
    In the field of materials science, it also has outstanding performance. With the rapid development of science and technology, the demand for new materials is increasing. This compound can be treated by special processes and integrated into polymer materials, giving the material unique electrical, optical or thermal properties. For example, in the field of organic photoelectric materials, it may improve the photoelectric conversion efficiency of materials and contribute to the development of photoelectric devices such as solar cells; or improve the fluorescent properties of materials, and apply it to fluorescent sensors to achieve highly sensitive detection of specific substances.
    Furthermore, in the stage of organic synthetic chemistry, it is an extremely important synthetic building block. Organic synthesis chemists, like skilled craftsmen, use various chemical reactions as basic units, splice and combine to create complex and diverse organic compounds. Through clever selection of reaction conditions and reagents, functional group transformation, cyclization and other reactions can be carried out to expand the structural diversity of organic compounds, injecting continuous vitality into the development of organic chemistry.
    In summary, 3,4-dihydroxythiophene-2,5-dimethyl diformate plays an indispensable role in the fields of medicine, materials and organic synthesis, just like a shining pearl, illuminating the way forward in many scientific fields.
    What is the synthesis method of 4-Dihydroxy-thiophene-2, 5-dicarboxylic acid dimethyl ester
    The synthesis of 3% 2C4-dihydroxy-thiophene-2% 2C5-dimethyl dicarboxylate is an important issue in the field of organic synthesis. To prepare this compound, the following methods are often followed.
    First, it can be started from a compound containing a thiophene ring. First, halogenate the thiophene ring at a specific position with a suitable halogenating agent to obtain a halogenated thiophene derivative. This process requires careful selection of halogenating agents and reaction conditions, such as temperature and solvent, to ensure that the halogenation reaction occurs precisely at the target check point.
    Then, the desired carboxyl precursor is introduced through reactions involving metal-organic reagents, such as Grignard reaction or palladium-catalyzed coupling reaction. Taking Grignard reaction as an example, the halogenated thiophene is made into Grignard reagent, then interacts with carbon dioxide, and then acidifies to obtain thiophene dicarboxylic acid intermediates.
    As for the introduction of hydroxyl groups, or in the early step, by nucleophilic substitution reaction, the halogen atom is replaced by a hydroxyl-containing reagent; or in the later stage, by functional group transformation, such as removing the appropriate protective group, the hydroxyl group is exposed.
    Finally, the obtained thiophene dicarboxylic acid is esterified. Methylation of carboxyl groups is achieved with methylation reagents such as dimethyl sulfate under alkali catalysis, and 3% 2C4-dihydroxy-thiophene-2% 2C5-dimethyl dicarboxylate is finally obtained. During the reaction process, the products of each step need to be purified, and methods such as column chromatography and recrystallization are commonly used to maintain the purity of the products and improve the yield. Each step needs to carefully control the reaction conditions in order to successfully achieve the synthesis of the target product.
    4-Dihydroxy-thiophene-2, 5-dicarboxylic acid dimethyl ester market prospects
    Today, there are 3% 2C4-dihydroxy-thiophene-2% 2C5-dimethyl dicarboxylate, and its market prospects are related to many aspects. This compound is expected to become a key raw material for innovative drugs in the field of medicine, or due to its unique chemical structure. For example, when developing targeted drugs for specific diseases, its structural properties may enable the drug to accurately act on the lesion and improve the curative effect, so the market demand for it may increase with the progress of medical research.
    In the field of materials science, it may be used to create new functional materials. Taking conductive materials as an example, through rational molecular design and modification, or endowing the material with unique electrical properties, it will find an application in the field of electronic device manufacturing, attracting the attention of related industries and generating new market demand.
    However, its market expansion also poses challenges. If the process of synthesizing the compound is complex and expensive, it will limit large-scale production and application, and hinder its marketing activities. And the market competition situation is also critical. If similar or alternative products emerge, its market share may be impacted.
    Furthermore, policies, regulations and environmental protection requirements have a great impact on its market prospects. If it conforms to the concept of green chemistry and meets environmental protection policies, it will be favored by the market; otherwise, it may face development difficulties due to strict environmental protection standards. In summary, the market prospect of 3% 2C4-dihydroxy-thiophene-2% 2C5-diformate has both opportunities and challenges. It is necessary to comprehensively consider all factors and seek a way to develop.
    What are the precautions for 4-Dihydroxy-thiophene-2, 5-dicarboxylic acid dimethyl ester in storage and transportation?
    3% 2C4 - Dihydroxy - thiophene - 2% 2C5 - dicarboxylic acid dimethyl ester is an organic compound. When storing and transporting, many matters need to be paid attention to.
    First words storage, this compound should be placed in a cool, dry and well ventilated place. Because it may be sensitive to temperature and humidity, high temperature and humid environment, it is easy to change its properties, or even chemical reactions and deterioration. Therefore, it is essential to choose a suitable storage environment. Furthermore, it is necessary to keep away from fire and heat sources to prevent the risk of fire. Because it may be flammable, it is dangerous to encounter open flames and hot topics.
    As for transportation, it should not be ignored. It is necessary to ensure that the packaging is complete and sealed to prevent leakage. If this material leaks during transportation, it will not only damage the substance itself, but also cause pollution to the environment, and even endanger the safety of the transporters. When transporting, it is advisable to choose appropriate means of transportation and follow relevant transportation regulations and operating procedures. During transportation, close attention should also be paid to temperature, vibration and other factors to avoid excessive vibration or sudden temperature changes affecting its stability.
    In short, when storing and transporting 3% 2C4 - Dihydroxy - thiophene - 2% 2C5 - dicarboxylic acid dimethyl ester, it is necessary to be cautious and pay attention to environmental conditions, packaging sealing and transportation specifications to ensure its quality and safety.