2 Thiophenesulfonyl Chloride 5 Methyl
quinoline thiophene imidazole thiazole

2-thiophenesulfonyl chloride, 5-methyl-

Taiy Chemical

    Specifications

    HS Code

    600874

    Chemical Formula C5H5ClO2S2
    Molecular Weight 196.67
    Appearance Typically a solid
    Color May be white or off - white
    Odor Pungent, characteristic sulfur - containing odor
    Melting Point Data needed
    Boiling Point Data needed
    Solubility In Water Low solubility, likely insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Density Data needed
    Stability Reactive, especially with nucleophiles

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    General Information
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    Frequently Asked Questions

    As a leading 2-thiophenesulfonyl chloride, 5-methyl- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-thienesulfonyl chloride, 5-methyl-?
    The physical properties of 2-% valeraldehyde glycol acetal, 5-methyl- are as follows:
    This substance is at room temperature, or a colorless and clear liquid. It is transparent and free of variegation, and there is no precipitation suspended in it. Smell, it has a special odor, not a pungent odor, but also has a unique smell, which can be identified in various odors.
    Its boiling point is quite critical, about a specific range of values. This value is the critical temperature at which it changes from liquid to gas at standard atmospheric pressure. The characteristics of boiling point are relevant to its application in distillation, separation, etc.
    Melting point is also an important physical property. At a certain temperature at the melting point of this substance, below this temperature, the substance is in a solid state and the structure is relatively stable; at this temperature, it begins to gradually transform into a liquid state.
    Density is also its significant characteristic. Compared with water, its density is either light or heavy. This characteristic affects its mixing and delamination with other substances in many chemical experiments and industrial applications.
    In terms of solubility, it may have good solubility in organic solvents and can be miscible with some organic solvents such as ethanol and ether to form a uniform solution. The solubility in water may be different, slightly soluble or insoluble, depending on the interaction between its molecular structure and water molecules.
    2-% valeraldehyde glycol, 5-methyl-based products, due to the above physical properties, have important application value in many fields such as chemical industry and medicine, and can be used as raw materials, solvents, etc., participating in various chemical reactions and production processes.
    What are the chemical properties of 2-thiophenesulfonyl chloride, 5-methyl-
    The physical properties of 2-% pentanone oxime and 5-methyl oxime are in need of detailed investigation in chemistry. These two have unique properties, related to their structure and reaction.
    First, 2-% pentanone oxime, whose molecule contains an oxime group, this structure gives it special reactivity. Oxime compounds can often react with many reagents, such as Beckmann rearrangement reaction under specific conditions. In this reaction, 2-% pentanone oxime rearranges to form a specific amide product, which is one of the important ways to form amide bonds in organic synthesis. And because of its molecular spatial structure and electron cloud distribution, it exhibits specific selectivity in some nucleophilic and electrophilic reactions.
    As for 5-methyl -, the presence of the linked methyl group affects the electron cloud density and spatial steric resistance of the molecule. Methyl groups are the power supply groups, which can increase the electron cloud density of the connected carbon atoms, which in turn affects the related reactivity. For example, in electrophilic substitution reactions, 5-methyl-derivatives are more likely to react than those that are not methylated, and the steric resistance of methyl groups also affects the stereochemistry of the reaction products. In some reactions involving spatial adaptation, such as enzyme-catalyzed simulated reactions, the spatial effect of 5-methyl - or the combination of the substrate and the activity check point changes, which affects the reaction rate and product configuration.
    The physical properties of the two are also different due to structural differences. Such as melting point and boiling point, affected by intermolecular forces, 2-% pentanone oxime oxime group can form hydrogen bonds, and its melting and boiling point may be different from that of 5-methyl-related compounds. In terms of solubility, the difference in molecular polarity determines its solubility in water and organic solvents. 2-% pentanone oxime oxime base is polar, or has good solubility in polar solvents; 5-methyl-oxime is non-polar, or more soluble in non-polar solvents. These physical differences are key considerations in separation, purification, and practical applications.
    What are the common synthesis methods of 2-thiophenesulfonyl chloride, 5-methyl-?
    To obtain 2-pentanone-5-methyl, there are several common synthesis methods.
    One of them can be synthesized by ethyl acetoacetate. Ethyl acetoacetate has a special active methylene, which can be alkylated with halogenated hydrocarbons. First, ethyl acetoacetate is formed under basic conditions, such as in the ethanol solution of sodium ethanol. Subsequently, 1-bromo-3-methylbutane is added, and the enol negative ion is used as a nucleophilic agent to attack the α-carbon atom of the halogenated hydrocarbon, and a nucleophilic substitution reaction occurs. A 5-methyl-3-pentyl group is introduced. Next, the product is hydrolyzed, and the ester group is hydrolyzed to a carboxyl group under the action of dilute acid. Finally, 2-pentanone-5-methyl can be obtained by decarboxylation by heating. The key to this method is to control the reaction conditions to ensure the selectivity and yield of the alkylation reaction.
    Second, the synthesis of diethyl malonate can be used. Diethyl malonate also contains active methylene, which can react with halogenated hydrocarbons in an alkaline environment, such as under the catalysis of sodium alcohol. First, diethyl malonate is alkylated with 1-bromo-3-methylbutane to build a carbon chain. After that, the product is hydrolyzed and decarboxylated. During hydrolysis, the disodium salt of malonic acid is hydrolyzed under alkaline conditions, and then acidified to obtain malonic acid. Malonic acid is easily decarboxylated by heat to obtain the target product 2-pentanone-5-methyl. This synthesis route needs to be controlled by the conditions of each step in the reaction process to improve the purity and yield of the product.
    Third, it can also be achieved by the reaction of Grignard reagents. Using 3-methyl butyraldehyde as the starting material, it is first reacted with Grignard reagents such as methylmagnesium bromide. The negatively charged carbon in the Grignard reagent attacks the carbonyl carbon atom of the aldehyde group to form a new carbon-carbon bond and generate the corresponding alcohol. Subsequently, the alcohol is oxidized, and a suitable oxidizing agent, such as chromium trioxide-pyridine complex (Collins reagent) or acidic solution of potassium dichromate, can be used to oxidize the alcohol to 2-pentanone-5-methyl. This method requires attention to the preparation and reaction conditions of Grignard reagent to avoid side reactions, so as to ensure the smooth progress of the reaction and obtain a higher yield.
    What is the main use of 2-thiophenesulfonyl chloride, 5-methyl-?
    2-% pentanone oxime, 5-methyl - The main use of this substance, in the book of "Tiangong Kaiwu", is mostly used in chemical industry and metallurgy.
    In the chemical industry, 2-% pentanone oxime, 5-methyl - is often the key raw material for organic synthesis. With its active chemical properties, it can participate in a variety of chemical reactions, such as condensation reactions with alaldehyde, ketone and other compounds, which can produce organic compounds with different structures. This is very useful in the preparation of polymer materials with special functions, pharmaceutical intermediates, etc.
    In the metallurgical industry, it can be used as an excellent metal corrosion inhibitor. When metals are exposed to various corrosive environments, 2-% pentanoxime, 5-methyl-can form a dense protective film on the metal surface, effectively inhibiting the corrosion process of metals. Taking common metals such as iron and copper as an example, their corrosion resistance is significantly improved after treatment, which is of great significance for prolonging the service life of metal products and reducing maintenance costs.
    Furthermore, in the coatings and paints industry, 2-% pentanoxime, 5-methyl-also has important functions. It can be used as an auxiliary agent for coatings to optimize the drying performance of coatings. It can accelerate the volatilization of solvents in the coating, promote the coating to dry quickly and form a film, and the quality after film formation is quite good, with good hardness and gloss, thereby improving the overall quality and performance of the coating.
    In some special catalytic reaction systems, 2-% pentanoxime, 5-methyl-can act as ligands, which can cooperate with metal catalysts to enhance the activity and selectivity of catalysts. This is very helpful for improving the efficiency of chemical reactions and accurately synthesizing target products. In the development process of modern organic synthesis chemistry, its position should not be underestimated.
    2-Thiophenesulfonyl chloride, 5-methyl - what are the precautions in storage and transportation?
    2-% valeraldehyde glycerol, 5-methyl - in storage and transportation, there are many points to pay attention to, all of which are related to the safety and effectiveness of the product, and must not be taken lightly.
    First of all, on storage, 2-% valeraldehyde glycerol and 5-methyl are active or active, and are prone to change in contact with various factors such as light, heat, and humidity. Therefore, when choosing a cool, dry and well-ventilated storage. It is necessary to avoid light, and it can be placed in dark bottles and cans to prevent its deterioration due to photochemical reactions. Temperature must also be controlled. If it is too high temperature, the molecules will be active, or the decomposition and polymerization will change. It is usually appropriate to keep it at room temperature or a specific low temperature range. In terms of humidity, humid gas is prone to hydrolysis and other chemical changes, so the storage place must be dry, and desiccant can be placed next to it to absorb water vapor.
    In addition to transportation, the packaging of these two must be solid and reliable during transportation. Choose suitable packaging materials, such as containers with corrosion resistance and excellent sealing, to prevent leakage. During loading and unloading, it is important to handle with care to avoid collisions, falls, and avoid packaging damage. And transportation vehicles need to have temperature control, moisture-proof and other equipment to maintain a suitable environment. During transportation, closely monitor, and if there are leaks, temperature abnormalities, etc., dispose of them quickly.
    In addition, whether it is storage or transportation, clear identification is the key. Mark the name, nature, danger, etc., so that relevant people can know how to deal with it. And in the storage and transportation place, fire protection and first aid equipment should be complete to prevent accidents. Professional training should also be carried out for operators to make them understand the nature and precautions of this object, so as to ensure the stability of storage and transportation without loss.