2-Thiophenepropanoic acid

2-Thiophene propionic acid, which has a wide range of uses. In the field of medicine, it is often used as a key intermediate. Genthiophene has a unique structure and can significantly change the physical, chemical and biological activities of compounds after introducing drug molecules. By means of chemical synthesis, based on 2-thiophene propionic acid, a variety of drugs with specific pharmacological activities can be prepared, such as some antibacterial and anti-inflammatory drugs, which can effectively deal with corresponding diseases and benefit the well-being of patients.
In the field of materials science, 2-thiophene propionic acid also has important uses. Due to its sulfur-containing heterocyclic structure, it can participate in many polymerization reactions, and then prepare polymer materials with specific properties. Such materials may have good electrical conductivity, optical properties, etc., and show broad application prospects in electronic devices, optoelectronic devices, etc., such as in organic Light Emitting Diode (OLED), solar cells, etc., to help the progress and development of related technologies.
In agriculture, 2-thiophenylpropionic acid can be made into plant growth regulators after rational derivation and transformation. It can regulate the process of plant growth and development, such as promoting seed germination, enhancing plant stress resistance, improving crop yield and quality, etc., providing strong support for the improvement and efficiency of agricultural production.
Overall, 2-thiophenylpropionic acid plays a key role in many fields such as medicine, materials, and agriculture, and is of great significance to promoting technological innovation and development in various fields.

2-Thiophene propionic acid is a kind of organic compound. It has the following physical properties:
Looking at its color state, at room temperature, it is white to light yellow crystalline powder, delicate and uniform, placed in light, slightly shiny. Its smell has a special aroma. Although it is not strong and pungent, it is unique. When you sniff it, it is different from the common floral and fruity aroma, and has a unique smell of chemical substances.
When it comes to the melting point, it is between 71 and 73 degrees Celsius. When the temperature gradually rises to this range, the compound will slowly melt from solid state to liquid state, like ice and snow meeting warm sun, quietly changing form. In this temperature range, the intermolecular forces change, the lattice structure disintegrates, and the ordered solid state is converted to a relatively disordered liquid state.
In addition to solubility, 2-thiophenylpropionic acid is soluble in many organic solvents, such as ethanol, ether, chloroform, etc. In ethanol, it can be rapidly dispersed and dissolved to form a uniform and transparent solution, just like salt dissolves in water, without particles, and appears uniform. This solubility is due to the specific interactions between its molecular structure and the organic solvent molecules, such as van der Waals forces, hydrogen bonds, etc., which promote the mutual fusion of the two. However, in water, its solubility is poor, only slightly soluble. This is due to the weak force between water molecules and 2-thiophene propionic acid molecules, which makes it difficult to overcome the force between its own molecules and dissolve in large quantities.
Its density is slightly larger than that of water. When placed in water, it will slowly settle to the bottom, like a stone entering water. Because its density is greater than the buoyancy of water, it sinks to the bottom. This density characteristic also reflects the tight arrangement of atoms inside its molecules and the relative mass size.

2-Thiophene propionic acid, whether this physical property is stable or not depends on various conditions. In the environment of room temperature and humidity, if there is no strong oxidation or reduction agent, or severe heat and light disturbance, 2-thiophene propionic acid is roughly stable.
Looking at its structure, thiophene rings have certain aromatic properties and give it certain chemical stability. The bond connected to propionic acid is not a weak bond that is easily broken. However, the chemical properties often change according to the environment. If exposed to strong acids and bases, its carboxyl or thiophene rings may react. In strong acids, the carboxyl group or protonation initiates a series of changes; in strong bases, the carboxyl group or salt is formed, and the thiophene ring may also react by nucleophilic attack.
Temperature is also key. At high temperatures, the kinetic energy of molecules increases sharply, and the reactivity is increased. 2-thiophene propionic acid may decompose, rearrange, or react with other substances in the environment.
Light should not be ignored. Although it is not a highly photosensitive object, long-term strong light irradiation or molecular excitation can trigger photochemical reactions and damage its stability.
In summary, 2-thiophenylpropionic acid is still stable under conventional conditions, but when specific chemical and physical conditions change, its stability is also affected, and its physical properties cannot be generalized to be stable.

The synthesis method of 2-thiophene propionic acid is not directly mentioned in the ancient book "Tiangong Kaizhi", but it can also be deduced from the ancient ideas and chemical methods.
First, it can be prepared by the addition reaction of thiophene and acrylic compounds. If thiophene is taken as the base, it can be added to acrylic acid under a suitable catalyst, temperature and pressure. It is necessary to choose a good catalyst, such as some transition metal complexes, to promote the efficient progress of the reaction. Temperature control is essential. If it is too high, side reactions will occur, and if it is too low, the reaction will be delayed.
Second, thiophene derivatives are used as the starting material. For example, 2-thiophene acetic acid is hydrocarbylated at the carboxyl α-position. First, 2-thiophene acetic acid is treated with a suitable alkali agent to form a carbon anion at the carboxyl α-position, and then reacts with halogenated hydrocarbons such as halopropane to introduce propyl to form 2-thiophene propionic acid. In the reaction, the type and amount of alkali and the activity of halogenated hydrocarbons need to be investigated in detail.
Third, sulfur-containing compounds and unsaturated acids can also be used to construct thiophene rings. Select suitable sulfur-containing reagents and acids with unsaturated bonds, and through multi-step cyclization, gradually build thiophene rings and introduce propionic acid side chains. This process is complicated, and the conditions of each step of the reaction need to be precisely adjusted, such as the proportion of reactants, reaction time, etc., to obtain high-purity 2-thiophene propionic acid. Each method has its own advantages and disadvantages, and it is necessary to consider the cost, yield, purity and other factors according to the actual needs, and choose carefully.

The price range of 2-thiophene propionic acid in the market is difficult to determine quickly. Its price often changes for many reasons, which is a common sense in the business market.
First, the quality has a huge impact on the price. If 2-thiophene propionic acid has extremely high purity and few impurities, it will definitely get a higher price; on the contrary, if the quality is slightly inferior and contains more impurities, the price will be lower.
Second, the purchase quantity is also the key. Generally speaking, for bulk buyers, because large quantities can reduce the cost and trouble of merchants, merchants may offer preferential prices; for small retail buyers, the price may be relatively high.
Third, the supply and demand situation of the market determines the price. If there are many people who want it, but the supply is limited, the so-called "rare goods are more expensive", and the price will rise; if the supply exceeds the demand, the merchants will try to reduce the price in order to sell their goods.
Fourth, the cost of production is also related. The price of raw materials, the production process, and the cost of manpower will all affect the final selling price. If the price of raw materials rises, or the cost rises due to the complexity of the process, the selling price will also be difficult to lower.
Overall, the price of 2-thiophene propionic acid ranges from tens of yuan to hundreds of yuan per kilogram. In order to know the exact price, it is necessary to consult the relevant chemical product suppliers in detail. They can provide accurate prices based on the current situation.