Chemical Formula | C6H8OS |
Molar Mass | 128.19 g/mol |
Appearance | Colorless to pale yellow liquid |
Boiling Point | 217 - 219 °C |
Density | 1.122 g/cm³ |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
Odor | Characteristic odor |
Flash Point | 96 °C |
Purity Typically Available | Often 95% or higher in commercial products |
What are the main uses of 2-Thiopheneethanol?
2-Thiophene ethanol is also an organic compound. It has a wide range of uses and is useful in various fields.
In the field of medicine, it is a key raw material for the synthesis of drugs. With its unique chemical structure, it can participate in a variety of drug synthesis pathways. It may improve the properties of drug molecules, such as improving the solubility and stability of drugs, and even enhancing their biological activity. Because the structure of organic compounds is often closely related to activity, 2-thiophene ethanol can be used as a structural unit to integrate drug molecules to achieve better pharmacological effects.
In the fragrance industry, it also plays an important role. It can give spices a special aroma. Due to its structure containing thiophene ring and ethanol group, the synergistic effect of the two can generate a unique odor, or have an elegant and fresh fragrance, which can add a unique flavor to the fragrance formula. It is used in perfumes, cosmetics, food flavors, etc., to enhance the richness and uniqueness of the fragrance.
In the field of materials science, 2-thiophene ethanol also plays a role. Or can participate in the synthesis of polymer materials. Its active groups can react with other monomers to form new polymer materials. Such materials may have special electrical and optical properties, such as in optoelectronic materials, which are expected to give materials good conductivity or fluorescence properties, opening up new directions for materials science.
In conclusion, 2-thiophene ethanol is an indispensable substance in the fields of medicine, fragrance, and materials due to its unique structure, and plays an important role.
What are the physical properties of 2-Thiopheneethanol?
2-Thiophene ethanol is one of the organic compounds. Its physical properties are unique, let me tell you one by one.
Looking at its properties, at room temperature, 2-thiophene ethanol is a colorless to light yellow transparent liquid with a clear appearance and no impurities visible to the naked eye.
Talking about the smell, it has a weak and specific aromatic smell, not pungent and intolerable, but has its own unique charm.
When it comes to the melting point, the melting point is about -28 ° C, and the boiling point is between 230-232 ° C. This boiling point characteristic makes it stable in liquid form under normal temperature environments.
Besides the density, its density is about 1.17g/cm ³, which is slightly higher than that of water, so if mixed with water, it will sink underwater.
In terms of solubility, 2-thiophene ethanol has good solubility in organic solvents, and common organic solvents such as ethanol, ether, and acetone can be mutually soluble with it. However, its solubility in water is limited and only slightly soluble. This difference in solubility is due to the characteristics of its molecular structure and the existence of organic groups, which make it more likely to go hand in hand with organic solvents.
In addition, 2-thiophene ethanol has low volatility and is not easy to evaporate quickly into the air. It has good stability during storage and use.
The above physical properties play a crucial role in the application of chemical engineering, medicine and many other fields, and are factors that need to be considered in relevant research and production practices.
Is 2-Thiopheneethanol chemically stable?
The chemical properties of 2-thiophene ethanol are more stable than those of other organic compounds. In its structure, the thiophene ring is connected to the ethanol group, and this unique structure endows it with several characteristics.
The thiophene ring is aromatic, which makes the molecular electron cloud distribution in a special state and is not easy to be moved by general weak chemical action. The ethanol group contains hydroxyl groups and can participate in specific reactions. However, due to the influence of the thiophene ring, the hydroxyl activity changes.
In common environments, if the conditions such as temperature and humidity do not change drastically, 2-thiophene ethanol can maintain a relatively stable state. In the case of ordinary oxidizing agents and reducing agents, without suitable catalytic conditions, the reaction is difficult to progress significantly.
However, its stability is not absolute. If placed in a strong acid, strong alkali environment, or under extreme conditions such as high temperature and high pressure, the molecular structure will be impacted. Strong acids and strong bases can react with hydroxyl groups and destroy the original chemical equilibrium of molecules; under high temperature and high pressure, the chemical bond between thiophene ring and ethanol group may change or break or rearrange.
Overall, the chemical properties of 2-thiophene ethanol are still stable within the range of conventional experiments and storage conditions. However, under special and severe conditions, its stability will be challenged, and the chemical structure and properties will change accordingly.
What are the preparation methods of 2-Thiopheneethanol?
For 2-thiophene ethanol, there are several ways to prepare it. First, thiophene is used as the starting point, and after lithiation, it interacts with ethylene oxide, followed by acidification to obtain this product. The process is as follows: thiophene is at low temperature and has an appropriate solvent such as tetrahydrofuran. When encountering n-butyllithium, lithium-substituted thiophene is produced. This lithium substitute reacts with ethylene oxide to obtain the corresponding alkoxide. After acidification, 2-thiophene ethanol is obtained.
Second, 2-thiophene acetic acid is used as the raw material. It is first reduced, and the commonly used reducing agent is lithium aluminum hydride. Under suitable reaction conditions, such as in anhydrous ether or tetrahydrofuran solvents, the carboxyl group of 2-thiophene acetic acid is reduced to a hydroxyl group, and then 2-thiophene ethanol is formed.
Third, use 2-chloromethylthiophene as the substrate. Make it react with nucleophiles, such as reacting with sodium ethanol in ethanol solution, nucleophilic substitution occurs, chlorine atoms are replaced by ethoxy groups, and then hydrolysis, 2-thiophene ethanol can also be obtained. These methods have their own advantages and disadvantages, depending on the ease of availability of raw materials, the difficulty of reaction conditions, and the high or low yield.
What is the price range of 2-Thiopheneethanol in the market?
The price of 2-thiophene ethanol in the market is difficult to determine. The rise and fall of its price often depends on various reasons.
First, it is related to raw materials. If the materials required for its production are widely available and affordable, the price of 2-thiophene ethanol may be stable and low. However, if the raw materials are rare and expensive, it is not easy to harvest, and the cost of production increases, the price will also rise.
Second, it depends on the process. If the production technology is excellent, the yield is high, the wear and tear is small, and the price of the finished goods is close to the people. If the technology is poor, it takes a long time, and the consumption is high and the profit is thin, the price will rise.
Third, the supply and demand of the market is necessary. If the demand exceeds the supply, the merchant will raise the price in pursuit of profit. If the supply exceeds the demand, the merchant will sell the goods or reduce the price for promotion.
Fourth, the change of political regulation and taxation also has an impact. If the strict tax increases, the cost of the merchant will increase, and the price will also increase. If the tax is reduced, the cost will be light, and the price may decrease.
Looking at the market conditions, the price of 2-thiophene ethanol ranges from tens to hundreds of yuan per kilogram, and it is difficult to determine the range of its price. It depends on the real-time situation.