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What are the physical properties of 2-thiophenecarboxylic acid, 5-acetyl-3-methyl
The physical properties of 2-% pentanone butyric acid and 5-ethoxy-3-propyl are related to its melting and boiling point, solubility, density, stability and other characteristics.
The melting and boiling point of this compound is determined by intermolecular forces. Its molecules contain functional groups such as carbonyl and ester groups, which cause van der Waals forces and hydrogen bonds between molecules. Carbonyl groups are polar and can increase the attraction between molecules, which increases the melting boiling point. However, although the growth of alkyl chains increases van der Waals forces, it also increases the intermolecular distance and affects the melting boiling point. It is estimated that its melting point may be between -20 ° C and -10 ° C, and the boiling point is about 200 ° C to 220 ° C. < Br >
In terms of solubility, due to the presence of polar functional groups and non-polar alkyl chains, it is amphiphilic. In polar solvents such as ethanol and acetone, polar functional groups can form hydrogen bonds with solvent molecules, showing good solubility. In non-polar solvents such as n-hexane and benzene, there is a van der Waals force between the non-polar alkyl chain and the solvent molecule, and there is also a certain solubility. However, in general, the solubility in water is not good. Due to the strong hydrogen bonds between water molecules, it is difficult for this compound to break its hydrogen bond network and integrate into it.
Density is related to molecular structure and composition. The relative mass and spatial arrangement of carbon, hydrogen and oxygen atoms in its molecules determine the density. Due to the presence of more carbon atoms and longer alkyl chains, the density is slightly smaller than that of water, and it is estimated to be between 0.95 g/cm ³ and 1.05 g/cm ³.
Stability depends on its chemical structure. The presence of carbonyl and ester groups makes the compound have certain reactivity. In case of strong acid and alkali, the ester group can be hydrolyzed, which affects the stability. At room temperature and pressure without special chemical environment, it has certain stability and can be stored and used under normal conditions. However, under high temperature, light or specific catalyst action, or decomposition, rearrangement and other reactions occur, it needs to be properly stored and used to avoid high temperature, light and strong acid-base environment.
What are the chemical properties of 2-thiophenecarboxylic acid, 5-acetyl-3-methyl
2-% pentanoic acid, 5-acetamido-3-methyl - The chemical properties of this compound are as follows:
From the structural point of view, it contains different groups such as ketoacid, amide group and methyl group, each group is endowed with its unique properties.
Ketoacid part: acidic, because the carboxyl group can dissociate hydrogen ions, it can exhibit certain acidic characteristics in aqueous solution and can neutralize with bases. For example, when reacting with sodium hydroxide, the hydrogen ion in the carboxyl group combines with the hydroxide ion to form water to form the corresponding carboxylate. The presence of ketone groups affects the electron cloud distribution of the compound, so that ketoacids have certain redox properties. Under certain conditions, ketone groups can be reduced to alcohol hydroxyl groups, or converted into other carbonyl derivatives by oxidation reaction.
Amide moiety: has certain stability, because its C-N bond has some double bond properties. However, under strong acid or strong base and heating conditions, amide groups can undergo hydrolysis. Under acidic conditions, hydrolysis produces carboxylic acids and ammonium salts; under basic conditions, hydrolysis produces carboxylic salts and ammonia or amines. The ethane group on the amide group in this compound also affects its chemical properties, such as changing the intermolecular forces, affecting the solubility and stability of the compound.
Methyl moiety: It is alkyl and has the properties of saturated hydrocarbons. The chemical properties are relatively stable, and it is not easy to react under general conditions. However, at high temperatures, light or in the presence of specific catalysts, the hydrogen atoms on the methyl group can be replaced by halogen atoms and halogenated reactions occur.
Overall, 2-% pentanoic acid, 5-acetamido-3-methyl-due to the interaction of various groups, makes its chemical properties rich and diverse. It may have unique uses in organic synthesis, medicinal chemistry and other fields. It can be used as an intermediate to participate in a variety of chemical reactions and synthesize more complex organic compounds.
What is the main use of 2-thiophenecarboxylic acid, 5-acetyl-3-methyl -?
2-%E5%99%BB%E5%90%A9%E7%94%B2%E9%85%B8, 5-%E4%B9%99%E9%85%B0%E5%9F%BA-3-%E7%94%B2%E5%9F%BA, is a kind of organic compound, which is important in various fields.
In the field of medicine, it is the key raw material for drug research and development. Due to the specific chemical structure, it can be precisely combined with the target in the body, and then exert therapeutic effect. For example, some antibacterial drugs, through the characteristics of this substance, can effectively inhibit the growth and reproduction of bacteria, and achieve the purpose of curing infections.
In the field of materials science, it can be used as the cornerstone of synthesizing special materials. Through ingenious chemical reactions, polymer materials with unique properties can be constructed. For example, polymers synthesized on this basis may have excellent mechanical properties and thermal stability, and are very useful in industries that require strict material properties such as aerospace and automobile manufacturing, making products lighter and stronger.
In agriculture, this compound also has its uses. It can be used to synthesize pesticides. With its special action mechanism against pests and pathogens, it can effectively protect crops from pests and diseases, ensure food yield and quality, and escort agricultural harvests.
In the field of scientific research and exploration, it is an important chemical reagent for scientists to study various chemical reaction mechanisms and explore the synthesis path of new compounds. Through in-depth exploration of its chemical properties, it can promote the development of organic chemistry, open up unknown chemical fields, and lay the foundation for the birth of more innovative achievements.
From this perspective, 2-%E5%99%BB%E5%90%A9%E7%94%B2%E9%85%B8, although 5-%E4%B9%99%E9%85%B0%E5%9F%BA-3-%E7%94%B2%E5%9F%BA is an organic compound, it plays an indispensable role in many fields such as medicine, materials, agriculture, scientific research, etc., and has made great contributions to the development and progress of human society.
What are the synthesis methods of 2-thiophenecarboxylic acid, 5-acetyl-3-methyl-
To prepare 2-carboxyglutaric acid, 5-acetamido-3-methyl-compound, the method is as follows:
First, a suitable starting material is used to gradually build the molecular structure through a multi-step reaction. Compounds with suitable carbon chain lengths and modifiable functional groups can be taken first, such as substrates containing suitable methyl groups and groups that can be converted into amide groups.
First, the substrate is modified at a specific location, and halogen atoms are introduced at an appropriate location for subsequent reactions using common reactions in organic synthesis, such as halogenation reactions. If the starting material is an alkyl compound, under the action of light or a specific catalyst, the halogen can be halogenated with a halogen to connect a specific carbon atom to a halogen, which can be used as an active check point for subsequent reactions.
Then an amidation reaction is carried out, and the introduced halogen group is replaced by an acetamide group through a substitution reaction. Acetamide can be used with a halogen-containing substrate in a suitable base and solvent system to cause the halogen atom to leave, and the acetamide group is connected to build a 5-acetamide group.
Then the carboxylation operation is carried out for the carbon chain, which is more critical. The corresponding Grignard reagent can be prepared by means of the Grignard reagent reaction, and the halogenated hydrocarbon and magnesium are reacted in a suitable solvent such as anhydrous ether. After that, the Grignard reagent is reacted with carbon dioxide, and after hydrolysis, a carboxyl group can be introduced at a specific position to form a 2-carboxyl group.
During the synthesis process, each step of the reaction needs to pay attention to the precise control of the reaction conditions, such as temperature, pH, reaction time, etc. If the temperature is too high or too low, the reaction may be biased towards side reactions, or the reaction rate is too slow, and the product yield is low. PH also affects the reaction process and product selectivity. And after each step of the reaction, effective separation and purification are required to ensure the purity of the product in each step and provide pure raw materials for the next reaction, so that the target compounds 2-carboxyglutaric acid, 5-acetamido-3-methyl can be synthesized efficiently and productively.
2-Thiophenecarboxylic acid, 5-acetyl-3-methyl - what are the precautions in storage and transportation?
2-%E5%99%BB%E5%90%A9%E7%94%B2%E9%85%B8, 5-%E4%B9%99%E9%85%B0%E5%9F%BA-3-%E7%94%B2%E5%9F%BA this compound in storage and transportation, pay attention to the following things:
First, because its chemical structure contains specific functional groups, the nature is more active. When storing, it should be placed in a cool, dry and well-ventilated place. Do not expose to direct sunlight, nor close to heat and fire sources, in case the temperature is too high to cause the compound to decompose and even burn, explosion and other disasters. Because of its volatility, if the storage environment temperature is too high, poor ventilation, gas accumulation, exposure to open fire or static electricity, it is prone to danger.
Second, during transportation, it must be properly packaged according to its chemical properties. Use containers that meet standards to ensure tight sealing to prevent leakage. This compound may have a corrosive effect on some materials, so the packaging materials must be carefully selected to avoid reaction with it. The loading and unloading process should be handled with care, and no violent vibration or impact should be used to avoid packaging damage.
Third, the compound may have certain toxicity and irritation. Whether it is a storage place or a transportation vehicle, it should be equipped with corresponding protective and emergency equipment. Such as gas masks, protective gloves, eye washers, etc., in case of emergency. Relevant operators should also receive professional training and be familiar with the characteristics of the compound and emergency treatment methods. In the event of a leak, personnel should be evacuated quickly, emergency procedures should be started, and appropriate measures should be taken according to the degree of leakage and site conditions. For example, inert materials should be adsorbed, collected, and then properly disposed of. It must not be allowed to flow into the environment to avoid pollution and harm.