As a leading 2-Thiophenecarboxaldehyde,5-cyano- (6CI,7CI) supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 2-Thiophenecarboxaldehyde, 5-cyano- (6CI, 7CI)?
2-Thiophenecarboxaldehyde, 5-cyano- (6CI, 7CI) is 5-cyano-2-thiophene formaldehyde, and its chemical structure is as follows: Thiophene is a sulfur-containing five-membered heterocyclic compound, composed of four carbon atoms and one sulfur atom to form a planar five-membered ring structure. An aldehyde group (-CHO) is connected at position 2 of the thiophene ring. The aldehyde group is connected by a single bond between a carbon atom and a hydrogen atom, and the carbon atom is connected by a double bond with an oxygen atom. A cyano group (-CN) is connected at position 5 of the thiophene ring, and the cyano group is connected by a carbon atom and a nitrogen atom in a triple bond. On the whole, in the molecular structure of 5-cyano-2-thiophene formaldehyde, the thiophene ring is used as the core skeleton, and the aldehyde group and the cyano group are in specific positions as substituents, which endows the compound with unique chemical properties. This structure makes it have the related reactivity of aldehyde and cyanyl groups. For example, aldehyde groups can undergo oxidation, reduction, condensation and other reactions, and cyanyl groups can undergo hydrolysis, addition and other reactions, which have important application value in the field of organic synthesis.
What are the main uses of 2-Thiophenecarboxaldehyde, 5-cyano- (6CI, 7CI)?
2-Thiophene formaldehyde, 5-cyano- (6CI, 7CI), has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate for the synthesis of many effective drugs. Due to its special chemical structure, it can cleverly react with other compounds to build molecular structures with specific biological activities, helping to create new antiviral, anticancer and antibacterial drugs, etc., to save the people from the source of disease.
In the field of materials science, it also has extraordinary functions. With this as a raw material, through exquisite processing, organic optoelectronic materials with excellent performance can be prepared. Such materials are shining in cutting-edge fields such as Light Emitting Diode and solar cells, improving the photoelectric conversion efficiency of devices, promoting innovation in energy utilization, and contributing to the great cause of energy conservation and environmental protection.
In organic synthetic chemistry, it is also an indispensable and important building block. With its unique activity, it can participate in a variety of complex organic reactions, such as nucleophilic addition and condensation, opening up a path for the synthesis of organic compounds with complex structures and specific functions, enriching the types of organic compounds, expanding the boundaries of chemical research, and creating new skills in the hall of chemistry. All of this shows that 2-thiophene formaldehyde, 5-cyano- (6CI, 7CI) are of great value in various fields, promoting scientific and technological progress and benefiting people's livelihood.
What are the physical properties of 2-Thiophenecarboxaldehyde, 5-cyano- (6CI, 7CI)?
2-Thiophene formaldehyde, 5-cyano- (6CI, 7CI) is an organic compound. Its physical properties are related to the morphology, melting and boiling point, solubility and other characteristics of this substance, and are extremely important in the fields of chemical industry and scientific research.
This substance may be a solid under normal conditions. Due to the cyanogen group and thiophene ring structure, intermolecular forces or cause it to appear solid. Its melting point and boiling point are affected by molecular structure. Cyanyl groups have strong polarity, which can enhance intermolecular forces and increase the melting boiling point. The conjugated structure of thiophene rings also affects molecular stability and force. According to the structure speculation, the melting point may be in a relatively high range, and more energy is required to overcome intermolecular forces and cause lattice damage.
In terms of solubility, the compound is slightly soluble in water due to its polar cyanyl group. Water is a polar solvent, and the polar cyanyl group can form a certain interaction with water molecules, but the thiophene ring is a non-polar part, which limits its dissolution in water. In organic solvents, such as ethanol, acetone and other polar organic solvents, because it has both polar and non-polar parts, or has good solubility. Because the polar part of the organic solvent can interact with the cyanyl group, the non-polar part interacts with the thiophene ring, which is conducive to dissolution.
In addition, the density of the compound may vary depending on the molecular structure and relative molecular weight. Due to the presence of sulfur, nitrogen and other atoms, the relative molecular weight is large, and the structure is compact, and the density may be higher than that of common hydrocarbon compounds
In conclusion, the physical properties of 2-thiophenylformaldehyde, 5-cyano- (6CI, 7CI) are determined by its unique molecular structure, which is of great significance for its application in various fields.
What are the synthesis methods of 2-Thiophenecarboxaldehyde, 5-cyano- (6CI, 7CI)?
2-Thiophene formaldehyde, 5-cyano (6CI, 7CI), there are many methods for synthesis, which is described by you today.
One method is to use 5-bromo-2-thiophene formaldehyde as the starting material. Shilling it and cuprous cyanide in a suitable solvent, such as N, N-dimethylformamide (DMF), at a certain temperature, co-heating. Cyanyl can replace bromo, and then obtain the target product. This reaction requires precise temperature control, and cuprous cyanide is highly toxic, and the operation should be extremely cautious.
There are 2-thiophene carboxylic acid as the starting point. It is first converted into an acyl chloride, which can be co-heated with thionyl chloride. Then the acyl chloride reacts with sodium cyanide in a suitable solvent, such as dichloromethane, to form 2-thiophenoformonitrile. After being reduced at low temperature by a specific reducing agent, such as diisobutylaluminum hydride (DIBAL-H), the nitrile group can be converted into an aldehyde group, and the final product is 5-cyano-2-thiophenylformaldehyde.
There is also a method of synthesis from thiophene through multi-step reaction. First, thiophene is acylated with suitable reagents, such as oxalyl chloride and aluminum trichloride, to obtain 2-thiophenoformyl chloride. The subsequent steps are similar to those started from 2-thiophenecarboxylic acid above, first forming nitrile and then reducing to aldehyde.
All synthesis methods have advantages and disadvantages. From the availability of raw materials, the difficulty of reaction, the yield and the safety of operation, all need to be weighed. When synthesizing, we must choose the best method according to the actual situation to achieve twice the result with half the effort.
What is the market outlook for 2-Thiophenecarboxaldehyde, 5-cyano- (6CI, 7CI)?
2-Thiophene formaldehyde, 5-cyano- (6CI, 7CI), the current market prospect of this product is the concern of many industry players and parties. In terms of its current situation, this compound has emerged in specific fields. In the field of pharmaceutical research and development, because of its unique chemical structure, it provides the possibility for the creation of new drugs, or can be used to synthesize pharmaceutical ingredients with specific physiological activities to deal with certain difficult diseases, which has attracted many pharmaceutical companies and scientific research institutions to invest in research, and the market demand is expected to grow.
In the field of materials science, it also shows potential application value. Or it can be used as a key component of functional materials, giving materials such as special optical and electrical properties to meet the specific needs of industries such as electronic devices and optical materials. With the vigorous development of such industries, the demand for 2-thiophene formaldehyde, 5-cyano- (6CI, 7CI) may be on the rise.
However, its market development also faces some challenges. The complexity of the synthesis process is high, resulting in high production costs, which may hinder its large-scale promotion and application. And related technologies still need to be improved, and market awareness needs to be further enhanced. If we can break through the bottleneck of synthesis technology, reduce costs, and increase publicity and promotion efforts to enhance the industry's awareness of its performance and application, the future market prospect of this compound is quite broad, and it is expected to expand the application territory in many fields, injecting new impetus into the development of related industries.