2-Thiophenebutyric acid

2-Thiophenobutyric acid, an organic compound, has important uses in many fields.
First, in the field of medicinal chemistry, it is a key synthesis intermediate. Through a series of chemical reactions, it can be converted into drug molecules with specific biological activities. For example, in some new drug development for specific diseases, 2-thiophenobutyric acid can act as a starting material. Through ingenious chemical modification and construction, drugs with high affinity for disease-related targets can be generated, which is expected to open up new avenues for the treatment of diseases.
Second, in the field of materials science, it is also useful. It can participate in the synthesis of polymer materials and give materials unique properties. For example, by polymerizing with specific monomers, it is possible to prepare materials with special optical, electrical or mechanical properties, or to enhance the stability and flexibility of materials, which play a role in the creation of electronic devices, optical thin films and other materials.
Third, in the field of organic synthesis, 2-thiophenobutyric acid can be used to construct more complex organic molecular structures due to its special structure. Chemists use its functional group properties to synthesize a series of organic compounds with novel structures through esterification, substitution and other reactions, providing a variety of materials for basic research and application development of organic chemistry.
In conclusion, although 2-thiophenobutyric acid may seem ordinary, it plays a significant role in many important fields such as medicine, materials, and organic synthesis, and is of great significance in promoting the development of related fields.

2-Thiophenobutyric acid is also an organic compound. Its physical properties are particularly important and are of great use in chemical engineering.
This substance is mostly in a solid state under normal conditions at room temperature. Its melting point is about [X] ° C, which may change slightly depending on the preparation method and purity. The determination of the melting point can be used to guide its purity and specific reactions.
Looking at its appearance, it is often white to off-white powder, with uniform texture, and its fineness can be seen. This appearance characteristic is easy to identify, and it also affects the preparation, mixing and other processes.
The solubility of 2-thiophenobutyric acid also has its properties. In organic solvents, such as ethanol, ether, etc., it is quite soluble, which makes it easy to disperse and participate in the reaction in organic synthesis reactions. However, in water, its solubility is limited. Due to the molecular structure, the thiophene ring containing sulfur and the butyric acid group have the dominant hydrophobicity, so it is difficult to dissolve in water.
Furthermore, its density is also a key physical property, about [X] g/cm ³. The value of density is related to the measurement and mixing ratio of materials, and is indispensable for the precise control of chemical production.
Its odor has a weak special smell, which is not pungent and unpleasant, but it is also different from odorless things. This odor characteristic needs to be paid attention to in the environmental considerations of production operation and product application.
Overall, the physical properties, melting point, appearance, solubility, density, and odor of 2-thiophenobutyric acid have a significant impact on its application in chemical, pharmaceutical, and other fields.

2-Thiophene butyric acid, the properties of this substance are related to the stability of its chemical properties. In terms of the ancient meaning of "Tiangong Kaiwu", if you want to explore its stability, you should look at its changes in various environments.
If it is at room temperature and pressure, 2-thiophene butyric acid is still stable. In its structure, the thiophene ring is connected to the butyric acid chain. The thiophene ring has a certain aromatic properties, which adds some stability to the structure. The butyric acid chain, although there is active hydrogen, is still stable as a whole. At room temperature, it does not respond rashly to common air components, such as nitrogen and oxygen.
When it encounters high temperature, the situation is different. Under high temperature, the kinetic energy of the molecule increases sharply, and the chemical bonds inside 2-thiophene butyric acid are unevenly stressed or broken. The thiophene ring may change when the ring is opened, and the butyric acid chain may also be decomposed, resulting in a major change in its chemical properties.
Furthermore, in an acid-base environment, its stability is also tested. In an acidic environment, the carboxyl group or protonation affects the charge distribution and reactivity of the molecule. In an alkaline environment, the carboxyl group is easy to form salts, and the alkalinity is too strong, and the thiophene ring may also be attacked, which damages the structure and makes it difficult for the chemical properties to remain intact.
In addition, if a specific chemical agent is encountered, such as a strong oxidant, the sulfur atom of the thiophene ring may be oxidized, Strong reducing agents may also break or reduce the carboxyl group, causing it to be unstable.
In summary, the chemical properties of 2-thiophenebutyric acid are stable, not generalized, stable at room temperature and under specific conditions, but at high temperatures, extreme acids and bases, and when specific reagents act, its stability is difficult to survive.

The preparation method of 2-thiophene butyric acid has been known for a long time, and is described in detail below.
First, it can be prepared by a specific reaction between thiophene and acrylic acid derivatives. In this way, suitable acrylic derivatives, such as acrylates, need to be selected. Under appropriate reaction conditions, the addition reaction occurs between the two. The temperature, pressure of the reaction environment, and the type and dosage of the catalyst are all key. If the reaction temperature is mild, about tens of degrees Celsius, a specific metal salt or an organic base is used as a catalyst to promote the unsaturated bond of the active check point of thiophene and the acrylic acid derivative to combine, thereby generating carboxylic acid esters containing thiophene structures. After the hydrolysis step, the ester group is converted into a carboxyl group, and the final 2-thiophene butyric acid is obtained.
Second, using thiophene as the starting material, a halogen atom, such as a bromine atom, is introduced into the thiophene ring through a halogenation reaction. Commonly used halogenation reagents include bromine, N-bromosuccinimide, etc. After generating halogenated thiophene, nucleophilic substitution reaction is carried out with succinic acid derivatives. The succinic acid derivative needs to have a suitable leaving group, such as a halogen atom or a sulfonate group. During the reaction, the halogen atom of the halogenated thiophene is replaced by the nucleophilic part of the succinic acid derivative to form a carbon-carbon bond. Subsequent to appropriate deprotection or functional group conversion steps, the functional group of the intermediate product is adjusted to a carboxyl group to complete the preparation of 2-thiophene butyric acid.
Third, there is also a Knoevenagel condensation reaction with diethyl malonate under alkaline conditions with aldodes containing thiophene structure as the starting material. The alkaline environment can be provided by bases such as sodium alcohol, and the reaction generates intermediate products containing double bonds. Subsequently, the double bonds are saturated by catalytic hydrogenation, and then the excess ester groups and carboxylic groups are removed through hydrolysis and decarboxylation to accurately obtain 2-thiophene butyric acid.
This number method has its own advantages and disadvantages. When preparing, it needs to be carefully selected according to factors such as the availability of raw materials, the difficulty of reaction, and the purity requirements of the product.

The prices of things in the market vary from time to time, and they also change with the supply and demand of the market and the quality of the things. As for 2-Thiophenebutyric acid, the price range of this thing is difficult to determine.
Taste the changes of the city, like the wind and clouds are impermanent. The prices of the past are always a lesson for the present, but in this world, there are various business paths, and new technologies emerge one after another. Therefore, the old rules cannot be completely relied on.
If you want to know the approximate price of this thing, you should study the cities carefully. Whether it is an organic city, or a company specializing in chemical industry, its price varies. Those who are of high quality must be expensive; and those who are inferior, the price may be slightly cheaper. < Br >
I also heard that the balance between supply and demand has a huge impact on the price. If there are many people seeking this product, but there are few suppliers, the price will increase; on the contrary, if the supply exceeds the demand, the price will drop.
Although it is difficult to determine the range of its price, from my point of view, in the common chemical market, the price may be between a few yuan per gram and a few tens of yuan. However, this is only speculation. The actual price should be subject to what is sold in the market. If you want to buy this product, you must go to the cities in person and inquire about its price in detail before you can get it.