2-Thiopheneacetonitrile,5-bromo-

2-Thiophene acetonitrile, 5-bromine - This substance has a wide range of uses and is useful in many fields.
In the field of organic synthesis, it is a key intermediate. It can be used to construct complex organic molecular structures through various chemical reactions. For example, through nucleophilic substitution reactions, it can combine with various nucleophilic reagents to expand the carbon chain of molecules, and then synthesize compounds with specific functions and structures. These synthesized compounds are of great significance in pharmaceutical research and development.
In the field of medicine, drugs prepared from this starting material may have therapeutic effects on specific diseases. For example, in some drug development for certain diseases such as inflammation and tumors, compounds derived from 2-thiophene acetonitrile and 5-bromine have shown potential biological activities, which can act on disease-related targets and provide the possibility for the creation of new drugs.
In addition, in the field of materials science, based on its unique chemical structure, the synthesized materials may have special electrical and optical properties. It can be applied to the preparation of organic optoelectronic materials, such as the manufacture of organic Light Emitting Diodes (OLEDs), to improve their luminous efficiency, stability and other properties, and to help optimize and improve the properties of materials.

2-Thiophene acetonitrile, 5-bromine - The physical properties of this substance are related to its morphology, melting boiling point, solubility and other characteristics. Under normal conditions, it may be a solid powder, and its color may be white to light yellow. Due to the introduction of bromine atoms in its chemical structure, its appearance is affected.
When it comes to melting point, the melting point increases due to the enhancement of intermolecular forces by bromine atoms, which is about a specific temperature range. However, the exact value varies depending on the degree of purification and measurement conditions. The boiling point also changes due to structural changes. Due to the increase of intermolecular forces, more energy is required to make it boil, so the boiling point also increases.
In terms of solubility, the performance of this substance in organic solvents varies depending on the properties of the solvent. It may have a certain solubility in polar organic solvents, such as ethanol and acetone, because its molecular structure has both polar and non-polar parts, and it can form intermolecular forces with polar solvents to help it dissolve. In water, due to the strong polarity of water molecules and the weak interaction with this substance, the solubility is very small.
And because its molecules contain atoms such as sulfur, nitrogen and bromine, its density is also different from that of common organic compounds, and the relative density is relatively high. The specific value can be accurately determined by experiments. And the stability of this substance to light and heat is also its important physical property. The presence of bromine atoms may increase their sensitivity to light, and when heated, the molecular structure may change, affecting stability.

To prepare 2-thiophene acetonitrile and 5-bromine, the method is as follows:
Take thiophene as the starting material first, and introduce bromine atoms at the 5th position by bromination. This bromination method can use liquid bromine in an appropriate solvent, such as dichloromethane, add an appropriate amount of catalyst, such as iron powder or iron tribromide, and react under temperature control. The aromatic ring of thiophene has a certain activity, and under the catalysis of bromine, 5-bromothiophene can be successfully obtained.
After 5-bromothiophene is obtained, it can be reacted with acetonitrile-related reagents to form a target. 5-Bromo-2-thiophenaldehyde can be formed by the reaction of 5-bromothiophene with N, N-dimethylformamide and phosphorus oxychloride in a variant of the Wilsmeier-Hacker reaction. This step requires temperature control and attention to the order of feeding to maintain yield. Then, 5-bromo-2-thiophene formaldehyde and a cyanide reagent, such as sodium cyanide or potassium cyanide, in a suitable solvent, an addition phase transfer catalyst, such as tetrabutylammonium bromide, through nucleophilic addition reaction, the aldehyde group is converted to cyano group, and the methylene is introduced into the α position, resulting in 2-thiophene acetonitrile, 5-bromide.
There may also be other methods, such as 5-bromothiophene and halogenated acetonitrile under the action of a strong base, such as sodium hydride or potassium tert-butyl alcohol, in an anhydrous polar solvent, such as N, N-dimethylacetamide, obtained by nucleophilic substitution reaction. In this process, attention should be paid to anhydrous and anaerobic operation to avoid side reactions. In short, all methods have advantages and disadvantages. In practice, we should choose the appropriate method according to the convenience of raw materials, the request of yield, and the calculation of cost.

2-Thiophene acetonitrile, 5-bromine-are highly toxic products, and many things need to be paid attention to when storing.
First, this medicine must be stored in a cool, dry and well-ventilated place. If the environment is warm and humid, or its properties change, its medicinal power will be damaged, and even dangerous chemical reactions will be caused. For example, warm heat will accelerate its decomposition rate, humid air or make it absorb moisture and deteriorate, which will affect its quality and safety.
Second, be sure to keep away from fire and heat sources. This medicine is very easy to explode. In case of open flames and hot topics, it can instantly cause combustion and explosion, endangering everything around. It is a storage place. Fireworks are strictly prohibited. Electrical equipment also needs to have explosion-proof function to prevent accidents.
Third, it needs to be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. Because of its active chemical nature, contact with the above substances can easily trigger violent chemical reactions, or produce toxic gases, or cause fire and explosion. If it encounters a strong oxidant, or triggers a fierce oxidation reaction, a large amount of energy is released.
Fourth, the storage container must be tightly sealed. Avoid contact with air to prevent oxidation and deterioration. And the container material needs to be suitable, and it should not react with the substance to ensure storage safety.
Fifth, the storage area should be equipped with suitable containment materials to prevent leakage. Once a leak occurs, it can be handled quickly and properly to reduce the harm. There must also be clear warning signs so that all personnel are aware of the danger.
In short, the storage of 2-thiophene acetonitrile and 5-bromine must be carried out with great care and strict compliance with all rules to ensure safety.

I look at your question, but I am inquiring about the market price of 2-thiophene acetonitrile and 5-bromine. However, the market situation is fickle, and the price also fluctuates with many factors, such as the state of supply and demand, raw material costs, production process difficulties, current business conditions, etc.
In the past, if the supply and demand of this product were still stable, the raw materials were abundant, and the process was mature, the price might be in a certain range. However, if the raw materials are scarce, the demand will exceed the supply, and the price will rise; on the contrary, if the supply exceeds the demand, the price will decline.
And in different places, the price will also vary due to differences in transportation costs and taxes. In bustling commercial ports, transportation is convenient, logistics is smooth, and prices may be slightly lower; in remote places, transportation is difficult, costs are superimposed, and prices may be high.
Furthermore, the competitive situation of market participants also affects their prices. Businesses compete for market share, or apply price strategies, resulting in fluctuations in prices.
Overall, in order to determine its accurate market price, it is necessary to carefully consider the current market conditions, or consult industry experts and market brokers, in order to obtain a more accurate value. It is difficult to say the approximate price.