2 T Butylthiophene
Quinoline Thiophene Imidazole Thiazole
2-T-BUTYLTHIOPHENE
Chemical Formula C8H10S
Molar Mass 138.23 g/mol
Appearance Colorless to light yellow liquid
Boiling Point 184 - 186 °C
Density 0.993 g/cm³ at 20 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Odor Characteristic sulfur - containing odor
Flash Point 65 °C
FAQ

What is the main use of 2-T-BUTYLTHIOPHENE?

2-tert-butylthiophene is an important category of organic compounds. Its main uses involve a wide range of chemical fields, and it is particularly critical in the synthesis of materials.

Cover is often a key monomer for the synthesis of polymer materials with special properties due to its unique chemical structure and active chemical properties. In the synthesis of functional polymers, 2-tert-butylthiophene can be integrated into the main chain or side chain of the polymer through specific polymerization reactions to give the material special photoelectric properties, such as the preparation of conductive polymers with excellent electrical conductivity. Such polymers are widely used in organic electronic devices, such as organic Light Emitting Diode (OLED), organic solar cells, etc. OLEDs have been widely used in display screen manufacturing due to their advantages such as self-luminescence, wide viewing angle, and fast response speed. 2-tert-butylthiophene has contributed to improving the luminous efficiency and stability of devices. In the field of organic solar cells, the polymers it participates in synthesis can effectively absorb and convert light energy, and improve the photoelectric conversion efficiency of batteries.

Furthermore, in the field of fine chemical synthesis, 2-tert-butylthiophene is also an intermediary for the preparation of a variety of high-value-added fine chemicals. It can be derived from various chemical reactions, such as substitution reactions, oxidation reactions, etc., to generate many compounds with complex structures and special functions. Such compounds may be key intermediates in the synthesis of pharmaceuticals and pesticides. In pharmaceutical research and development, some intermediates containing 2-tert-butylthiophene structures can be converted through subsequent reactions to obtain drug molecules with specific biological activities, providing new avenues for disease treatment. In terms of pesticide creation, pesticide products with high efficiency, low toxicity, and environmentally friendly characteristics can be synthesized, contributing to the green development of agriculture. Due to the stability of the thiophene ring structure and the steric hindrance effect of tert-butyl, 2-tert-butylthiophene is often used as a basic module for the construction of special structures in organic synthesis reactions. With its unique properties, chemists can design and construct novel organic molecular frameworks, expand the boundaries of organic synthetic chemistry, and promote the continuous development of organic chemistry. It provides a rich material foundation and theoretical support for the research and development of new materials and new drugs.

What are the physical properties of 2-T-BUTYLTHIOPHENE?

2-Tert-butylthiophene, its physical properties are as follows:

This substance is mostly liquid at room temperature, and the appearance is clear and transparent. It has a specific odor, but this odor is difficult to describe accurately in words, with a slightly special organic compound smell.

About the melting point, it is usually in a relatively low range. The specific value may vary slightly depending on different measurement conditions, and it is roughly [specific melting point value, because the literature does not mention temporary]. This low melting point characteristic makes it easy to maintain a liquid state at room temperature.

In terms of boiling point, it is generally near [specific boiling point value, because the literature does not mention temporary]. This boiling point value shows that it can be converted from liquid to gaseous state under certain temperature conditions. The density of

is about [specific density value, because it is not mentioned in the literature]. Compared with common organic solvents, the density may be slightly different. This density characteristic has an important impact on the distribution and separation operation of various mixed systems.

Solubility is critical. 2-tert-butylthiophene is soluble in many organic solvents, such as ethanol, ether, benzene, etc. This good solubility facilitates its use as a reactant or solvent in organic synthesis and related chemical operations. In water, its solubility is very small, and its interaction with water is weak due to the dominance of hydrophobic groups in its molecular structure.

In addition, the refractive index of 2-tert-butylthiophene is also an important physical property. Under the irradiation of a specific wavelength of light, its refractive index is about [specific refractive index value, because the literature does not mention it temporarily]. This value can be used to identify the purity and concentration of this compound.

What are the chemical properties of 2-T-BUTYLTHIOPHENE?

2-tert-butyl thiophene is one of the organic compounds. It has special chemical properties and is widely used in the field of organic synthesis.

Structurally, the thiophene ring is a five-membered heterocycle containing a sulfur atom, which endows the compound with aromatic properties. Connected to tert-butyl at the 2-position, this large group has a significant impact on its chemical properties.

In terms of physical properties, it is mostly liquid at room temperature and has a certain volatility. Due to the sulfur atom, the smell may have a special taste. Its relative density, boiling point, melting point and other physical constants are different from those of the thiophene parent due to the existence of tert-butyl. Usually, the boiling point will increase due to the intermolecular force of the increase of tert-butyl.

Chemically, 2-tert-butylthiophene can undergo electrophilic substitution reaction due to the aromaticity of the thiophene ring. The electron cloud density distribution of the thiophene ring is affected by the sulfur atom and the tert-butyl group. Tert-butyl is the power supply group, which increases the electron cloud density of the thiophene ring, especially in the adjacent and para-positions, so electrophilic substitution reaction easily occurs in these positions. If it reacts with halogenating reagents, halogenated products can be formed; if it reacts with acylating reagents, acylated products can be obtained.

In addition, the carbon-sulfur bond in 2-tert-butylthiophene has certain activity, and cracking or transformation reactions can occur under specific conditions. In some catalytic systems, this compound can participate in more complex reactions, realize the construction of carbon-carbon bonds and carbon-heteroatomic bonds, and provide an effective way for the synthesis of complex organic molecules.

2-tert-butylthiophene plays an important role in materials science, pharmaceutical chemistry and other fields due to its unique chemical properties, and is an important object of organic synthetic chemistry research.

What is the production method of 2-T-BUTYLTHIOPHENE?

The preparation method of 2-tert-butylthiophene is not detailed in the ancient book "Tiangong Kaiwu", but it can be deduced from the principles of chemical engineering and the wisdom of ancient methods.

First, it can be obtained by the reaction of thiophene with tert-butylated reagents. Thiophene, an aromatic five-membered heterocyclic compound, has a specific electron cloud density distribution on its ring, which is prone to electrophilic substitution. Tert-butylated reagents, such as tert-butyl halides (tert-butyl chloride, tert-butylbromide, etc.), can react with thiophene under the action of appropriate catalysts. Anhydrous aluminum trichloride is used as a catalyst, which is used in the classic Fu-gram alkylation reaction. In the reaction system, anhydrous aluminum trichloride interacts with tert-butyl halide to form a tert-butyl carbon positive ion. This positive ion has electrophilicity and attacks the thiophene ring, replacing the hydrogen atom on the ring, and then obtaining 2-tert-butyl thiophene. During the reaction, attention should be paid to the reaction temperature, the proportion of reactants and the amount of catalyst. If the temperature is too high, it is easy to form multiple substituted products; if the proportion is improper, it will affect the yield; if there is too much or too little catalyst, it will also disturb the reaction rate and product purity.

Second, it may be obtained by the conversion of thiophene derivatives. First prepare a thiophene derivative containing a suitable substituent, which is converted into tert-butyl through a specific reaction. For example, first obtain thiophene derivatives containing halogen atoms, react with metal-organic reagents such as Grignard reagent (tert-butyl magnesium bromide, etc.), and the halogen atom is replaced by tert-butyl to obtain 2-tert-butyl thiophene. In this process, the preparation and use of metal-organic reagents need to be under anhydrous and oxygen-free conditions, because they are extremely sensitive to water and oxygen, and are prone to side reactions, resulting in failure of the reaction. And the post-reaction treatment also needs to be careful to remove impurities and obtain a pure product.

Although there is no ready-made method of "Tiangong Kaiji", according to chemical principles and existing methods, 2-tert-butyl thiophene can be prepared.

What are the precautions for using 2-T-BUTYLTHIOPHENE?

2 - tert-butylthiophene, when using, there are several precautions to be aware of.

The first thing to pay attention to is its physical and chemical properties. This substance has specific physical properties and chemical activity. Its appearance may be a certain form, and it has a certain response to environmental factors such as temperature and humidity. If the environment is not suitable for temperature and humidity, or causes its properties to change abnormally, it will affect the use effect. If it is in a hot and humid place, it may accelerate its chemical change, reduce the purity, and then affect the chemical reaction process and product quality involved.

Furthermore, safety protection must not be ignored. 2 - tert-butylthiophene may be toxic, irritating, or flammable and explosive. When in contact, be sure to follow the specifications of protective equipment, such as protective gloves, goggles, gas masks, etc., to prevent contact with the skin, eyes, or inhalation of its volatile gas, causing physical discomfort. The operation site also needs to be well ventilated to disperse volatile gases and reduce the risk of explosion. If used in a closed space, volatile gas accumulates, and in case of open fire or hot topic, there is a danger of deflagration.

During use, accurate dosage control is also key. Its role in chemical reactions is often closely related to dosage. Too much or too little dosage may cause the reaction to deviate from expectations. At least the reaction is incomplete and the product yield is low; at most, it may lead to side reactions, which increase the impurities of the product and greatly increase the difficulty of subsequent separation and purification.

In addition, the method of storage should not be underestimated. Choose a cool, dry and ventilated place, away from fire and heat sources. And it needs to be stored separately from oxidants, acids, etc., and should not be mixed. Due to improper storage, it will chemically react with other substances, which will not only damage itself, but also cause dangerous conditions.

In short, the use of 2-tert-butylthiophene should be done with caution in terms of physical and chemical properties, safety protection, dosage control, storage, etc., in order to ensure the safety and effectiveness of use.