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What is the chemical structure of 2- [ (pyridin-3-ylcarbonyl) amino] ethyl thiophene-2-carboxylate
This is about the chemical structure of "2 - [ (pyridine-3-carbonyl) amino] ethylthiophene-2-carboxylate". This compound is composed of thiophene-2-carboxylate, pyridine-3-carbonyl and aminoethyl.
Looking at its structure, thiophene-2-carboxylate is the basic structure, thiophene is a sulfur-containing five-membered heterocycle, and its 2 positions are connected by an ester group, that is, -COO-R structure. This ester group endows the compound with specific chemical activity and physical properties. In the pyridine-3-carbonyl group, pyridine is a nitrogen-containing hexamembered heterocycle with a 3-position connection to carbonyl-C = O, and the carbonyl group is electrophilic and can participate in many chemical reactions. Aminoethyl has the structure of -NH-CH-CH, and the amino group is nucleophilic and can react with electrophilic groups such as carbonyl groups.
The three are connected, and the carbonyl group of pyridine-3-carbonyl and the amino group of aminoethyl condensate to form an amide bond - CONH -, which is stable and characteristic. The other end of the amino ethyl group is connected to the ester group of thiophene-2-carboxylic acid ester, and then the complete chemical structure of 2-[ (pyridine-3-carbonyl) amino] ethylthiophene-2-carboxylic acid ester is formed. This structure endows the compound with unique chemical and physical properties, and may have important uses in organic synthesis, medicinal chemistry and other fields.
What are the physical properties of 2- [ (pyridin-3-ylcarbonyl) amino] ethyl thiophene-2-carboxylate
2-%5B%28pyridin-3-ylcarbonyl%29amino%5Dethyl thiophene-2-carboxylate (2- [ (pyridine-3-carbonyl) amino] ethylthiophene-2-carboxylate) is an organic compound, and its physical properties are as follows.
Looking at its appearance, it is often in the state of white to off-white solid powder. This is a common property of many organic compounds due to its molecular arrangement and interaction.
When it comes to the melting point, the melting point of this substance is about [X] ° C. The melting point is the temperature at which a substance changes from a solid state to a liquid state. For this compound, this temperature reflects the strength of its intermolecular forces. When the temperature reaches the melting point, the molecules are energized enough to overcome the attractive force between each other, and the lattice structure disintegrates, thus forming a liquid state.
In terms of solubility, it exhibits good solubility in organic solvents such as dichloromethane and chloroform, due to the similar miscibility principle. The molecular structure of the compound can form appropriate interactions with the molecules of these organic solvents, such as van der Waals force, dipole-dipole interaction, etc., to help it disperse in the solvent. However, the solubility in water is very small, and the hydrophobic part of the molecule accounts for a large proportion, making it difficult to form effective interactions with water molecules, and the hydrogen bond network of water is difficult to accept the compound molecule.
In addition, the compound has a certain stability. Under normal temperature and pressure, its chemical structure can be maintained relatively stable without special chemical reagents or conditions. In case of extreme conditions such as high temperature, strong oxidants or strong bases, its structure may change and chemical reactions occur, because these conditions can break the original chemical bonds in the molecule and cause new chemical changes.
In conclusion, the physical properties of 2 - [ (pyridine-3-carbonyl) amino] ethylthiophene-2-carboxylic acid esters, such as appearance, melting point, solubility and stability, are of great significance to their applications in organic synthesis, drug development and other fields. Researchers need to design experiments and application scenarios reasonably according to their characteristics.
What is the synthesis method of 2- [ (pyridin-3-ylcarbonyl) amino] ethyl thiophene-2-carboxylate
To prepare 2 - [ (pyridine-3-ylcarbonyl) amino] ethylthiophene-2-carboxylic acid ester, the method is as follows:
First take thiophene-2-carboxylic acid, place it in a clean reactor, dissolve it with an appropriate amount of alcohol solvent, and then add a suitable catalyst, such as concentrated sulfuric acid. Heat up to an appropriate temperature to make it esterified with alcohols such as ethanol. This process requires careful temperature control and close monitoring of the reaction process. When the reaction reaches the desired level, thiophene-2-carboxylic acid ethyl ester is obtained.
Then, slowly add pyridine-3-carboxylic chloride to an amine-containing reagent, such as ethylenediamine, and react under mild conditions to generate an amine intermediate containing pyridine-3-carboxylic group. Pay attention to the pH and temperature of the reaction system during the reaction to prevent side reactions.
Finally, the thiophene-2-carboxylic acid ethyl ester obtained above meets the amine intermediate containing pyridine-3-carboxylic group, and reacts in a suitable basic environment, such as potassium carbonate and other bases, in a suitable solvent. After the reaction is completed, impurities are removed by separation and purification techniques, such as column chromatography, recrystallization, etc., and pure 2- [ (pyridine-3-ylcarbonyl) amino] ethylthiophene-2 -carboxylic acid esters are obtained.
Throughout the synthesis process, every step needs to be carefully controlled to control the reaction conditions to improve the purity and yield of the product.
What are the application fields of 2- [ (pyridin-3-ylcarbonyl) amino] ethyl thiophene-2-carboxylate
2-%5B%28pyridin-3-ylcarbonyl%29amino%5Dethyl thiophene-2-carboxylate, it is an organic compound. Its application field is quite extensive, and it is described as follows:
In the field of medicinal chemistry, such compounds may have potential biological activity. The unique molecular structure may interact with specific targets in vivo. For example, its pyridine and thiophene structural units may conform to the activity check point of some enzymes, thereby affecting the catalytic function of enzymes. Therefore, in drug development, it may be used as a lead compound. After structural modification and optimization, it is expected to develop new therapeutic drugs, such as anti-cancer, anti-inflammatory or antibacterial drugs.
In the field of materials science, the compound is also promising. Because they contain specific functional groups or can participate in polymerization reactions, polymer materials with special properties can be prepared. Such materials may have good photoelectric properties and can be used in optoelectronic devices such as organic Light Emitting Diodes (OLEDs) and solar cells to help improve the performance and efficiency of the devices.
Furthermore, in agricultural chemistry, such compounds may exhibit insecticidal, bactericidal or herbicidal effects. Their structural characteristics may enable them to interfere with the physiological processes of pests and achieve the purpose of protecting crops. For example, they may inhibit the function of the nervous system of pests or hinder the synthesis of pathogen cell walls, thus providing new ways and means for agricultural pest control.
In summary, 2-%5B%28pyridin-3-ylcarbonyl%29amino%5Dethyl thiophene-2-carboxylate has potential application value in many fields such as medicine, materials and agriculture, which is worthy of further exploration and development by researchers.
What is the market outlook for 2- [ (pyridin-3-ylcarbonyl) amino] ethyl thiophene-2-carboxylate
2-%5B%28pyridin-3-ylcarbonyl%29amino%5Dethyl thiophene-2-carboxylate, this is an organic compound, and its market prospects can be viewed from various aspects.
Bearing the brunt, in the field of pharmaceutical research and development, organic compounds are often key raw materials. In the creation of many new drugs, it is necessary to use such compounds with specific structures as starting materials to synthesize drug molecules with specific pharmacological activities through multi-step reactions. If this compound has a unique chemical structure and potential biological activity, the demand for it may be increasing in pharmaceutical companies or scientific research institutions. If the research and development of new anti-cancer and antiviral drugs is hot in recent years, if this compound can participate in the relevant drug synthesis path, the market prospect is bright.
Furthermore, in the field of materials science, some organic compounds can be used to prepare functional materials, such as optoelectronic materials, after special treatment. If the compound has unique performance in physical properties such as light and electricity, it may be applied to organic Light Emitting Diode (OLED), solar cells and other fields. With the vigorous development of electronic equipment and new energy industries, the demand for such materials continues to rise, and this compound may be favored by the market because it can meet specific material performance requirements.
However, its market also has challenges. The synthesis process of organic compounds may be complex, and cost control is difficult. If the synthesis process requires rare reagents and harsh reaction conditions, the production cost will rise, limiting its large-scale application. And the market competition is intense, and similar or similar functional compounds or existing ones, if they want to stand out, they need to be superior in performance, cost, environmental protection and other aspects.
Overall, 2-%5B%28pyridin-3-ylcarbonyl%29amino%5Dethyl thiophene-2-carboxylate an addressable market opportunity, especially in the fields of medicine and materials. However, in order to fully tap the market potential, it is necessary to overcome problems such as synthesis costs and enhance its own competitiveness in order to gain a firm foothold in the market and gain a considerable market share.