Chemical Formula | C5H6S |
Molar Mass | 98.166 g/mol |
Appearance | Colorless to light yellow liquid |
Odor | Thiophene - like odor |
Density | 1.029 g/cm³ at 20 °C |
Boiling Point | 112 - 114 °C |
Melting Point | -70 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Flash Point | 15 °C |
Vapor Pressure | 3.74 kPa at 25 °C |
Refractive Index | 1.5285 at 20 °C |
What are the physical properties of 2-methylthiophene?
2-% methylpyridine, also known as α-methylpyridine, is an important member of the family of organic compounds. It has the following physical properties:
Under normal temperature and pressure, 2-methylpyridine is a colorless to light yellow transparent liquid, clear and clear, like a spring on an autumn night. Its unique smell emits a special smell like pyridine. Although it is not rich and fragrant, it is unique, and it is unique in the kingdom of organic compounds.
When it comes to boiling point, the boiling point of 2-methylpyridine is about 129-131 ° C. At this temperature node, molecules are able to break free from each other's attractive forces and sublimate from the liquid state to the gaseous state, just like a butterfly breaking the cocoon and starting a new physical form journey. This boiling point characteristic is of great significance in the temperature control of separation, purification and chemical production. It is like a precise beacon, guiding the temperature channel of the production process.
In terms of melting point, its melting point is about -63.2 ° C. When the ambient temperature drops below this point, the originally flexible liquid molecules are like being cast a body-fixing spell, gradually arranged in a regular manner, solidified into a solid state, just like the ice seal on the lake in winter, from dynamic to static. This melting point data is like a solid foundation in the field of material storage and transportation conditions, laying the foundation for ensuring material stability and integrity.
2-Methylpyridine has a density of about 0.9519g/cm ³, which is slightly lighter than water. It is like a light boat on water and can float on the water surface. This density property, in the chemical mixing process and material stratification identification work, is like a precise ruler, helping professionals to clarify the distribution and interaction of substances.
Solubility is also an important physical property. 2-Methylpyridine can be miscible with common organic solvents such as water, ethanol, and ether in any ratio. In water, it is like a wanderer returning home, blending intimately with water molecules to form a uniform and stable mixed system; in organic solvents, it can also be compatible with each other, such as old friends reuniting and coexisting harmoniously. This excellent solubility makes it a powerful choice in many aspects such as chemical reaction medium selection and product separation, like a master key, opening the door to many chemical processes.
What are the chemical properties of 2-methylthiophene?
2-% methylimidazole, which is a colorless to light yellow-brown liquid, is very important in the chemical industry. Its chemical properties are unique and have many remarkable characteristics.
One is weakly basic. 2-Methylimidazole molecules contain nitrogen atoms, which contain lone pairs of electrons and can accept protons, exhibiting weakly basic characteristics. In chemical reactions, this alkalinity allows it to react with acids to form corresponding salts. For example, when it encounters hydrochloric acid, 2-methylimidazole hydrochloride is formed. This property is crucial in the preparation of certain ionic liquids because it can be combined with specific acids through acid-base neutralization reactions to create ionic liquid systems with unique properties.
Second, it has high reactivity. The imidazole ring structure of 2-methylimidazole gives it high reactivity. In the field of organic synthesis, it is often used as a ligand. Because the lone pair electrons on the nitrogen atom can coordinate with metal ions to form a stable complex. This complex is excellent in catalytic reactions and can effectively catalyze many organic reactions, such as esterification reactions and cyclization reactions. At the same time, in some polymerization reactions, 2-methylimidazole can act as a curing agent. For example, during the curing process of epoxy resins, it can react with epoxy groups in epoxy resins, and the epoxy resins can be converted from liquid to solid through cross-linking, which greatly enhances the mechanical properties and chemical stability of the materials.
Third, good thermal stability. Within a certain temperature range, 2-methylimidazole can maintain its own structural stability. This thermal stability makes it important in some high-temperature reactions or high-temperature environment application scenarios. For example, in some polymerization reactions or catalytic reactions that need to be carried out at higher temperatures, 2-methylimidazole can maintain its chemical structure and properties during the reaction process, and continue to play a role without rapid decomposition or deterioration due to temperature increase.
What are the main uses of 2-methylthiophene?
2-% methylimidazole has a wide range of uses and has important applications in many fields.
In the field of organic synthesis, 2-methylimidazole is a key intermediate. With its unique chemical structure, it can participate in many chemical reactions and help build complex organic molecular structures. For example, in the synthesis of heterocyclic compounds, 2-methylimidazole can be used as a core raw material to cleverly react with other reagents to generate various heterocyclic compounds with specific properties and biological activities. These compounds are of great significance in the field of drug development or can become a key structural unit of new drugs.
In the field of materials science, 2-methylimidazole also plays a pivotal role. It can act as a ligand and interact with metal ions to form metal-organic framework materials (MOFs). Such materials have a unique pore structure and large specific surface area, and are excellent in gas adsorption and separation, which can efficiently separate specific components in mixed gases. In the field of catalysis, MOFs materials exhibit excellent catalytic activity and selectivity due to the participation of 2-methylimidazole, which can greatly improve the efficiency and quality of chemical reactions.
In the field of epoxy resin curing agents, 2-methylimidazole is also indispensable. It can significantly accelerate the curing speed of epoxy resins, while optimizing the properties of cured products, such as increasing hardness and enhancing wear resistance. Epoxy resin products cured by 2-methylimidazole are widely used in electronic packaging, coatings and other industries, which greatly improves the quality and service life of products.
In the field of medicine and chemical industry, the derivatives synthesized by 2-methylimidazole have antibacterial, antiviral and other biological activities, providing new directions and possibilities for pharmaceutical research and development, or can develop new drugs to deal with specific diseases.
In short, 2-methylimidazole, with its diverse uses, plays a key role in many fields such as organic synthesis, materials science, epoxy resin curing, and medicine and chemical industry, and is of great significance to promote the development of various fields.
What are the synthesis methods of 2-methylthiophene?
The synthesis method of 2-% methylimidazole has been known in ancient times, and is described in detail below.
One is a method using glyoxal, formaldehyde and ammonia as raw materials. Among them, glyoxal and formaldehyde can be obtained by condensation reaction under the action of ammonia. The reaction mechanism is that the carbonyl group of glyoxal and the carbonyl group of formaldehyde interact and condensate in the basic environment provided by ammonia, and gradually construct the five-membered ring structure of imidazole. This process requires attention to the regulation of the reaction temperature and the proportion of reactants. If the temperature is too high, side reactions will occur frequently and the product will be impure. Improper ratio will also affect the yield. Generally speaking, the temperature should be controlled within a moderate range, and the reactants should be mixed according to a specific molar ratio, so that the reaction can proceed smoothly and obtain a better yield.
The second is the way to use 4-methylimidazole as raw material. 4-methylimidazole can be changed to 2-methylimidazole after a specific chemical conversion. This conversion often requires the help of suitable reagents and conditions, or reaction steps such as oxidation and rearrangement. For example, the use of a suitable oxidizing agent, in a specific reaction system, modifies the structure of 4-methylimidazole to migrate the position of methyl groups, and then achieves the synthesis of 2-methylimidazole. However, this method requires strict reaction conditions. The choice of oxidant and the control of reaction time are all related to the quality and yield of the product.
Furthermore, imidazole is used as the starting material, and 2-methylimidazole can also be prepared through methylation. This methylation process requires the selection of suitable methylating reagents, such as iodomethane, dimethyl sulfate, etc. Under basic conditions, imidazole undergoes nucleophilic substitution with methylating reagents, and methyl is then introduced into the 2-position of the imidazole ring. During operation, it must be noted that the activity of the methylating reagent is very high, which is dangerous, and the separation and purification after the reaction also requires fine operation to obtain pure 2-methylimidazole in addition to unreacted raw materials and by-products. < Br >
All these synthetic methods have their own advantages and disadvantages. In practical applications, the choice should be weighed against many factors such as the availability of raw materials, cost, and product quality requirements.
What are the precautions for 2-methylthiophene during storage and transportation?
There are three things to pay attention to when 2-% methylfuranone is stored and transported. First, it is related to its stability. This substance is active in nature, and is prone to chemical reactions and deterioration when exposed to heat, light, oxygen and other factors. Therefore, it should be stored in a cool, dry and dark place, and the temperature should be controlled within a specific range to prevent decomposition due to excessive temperature. And it needs to be tightly sealed to prevent it from coming into contact with the air, because oxygen in the air will cause it to oxidize and affect the quality.
Second, it is safety. 2-% methylfuranone has certain toxicity and irritation, and is irritating to the eyes, skin and respiratory tract. During storage and transportation, operators must operate in strict accordance with safety procedures, wear protective clothing, gloves, goggles and other protective equipment, and avoid direct contact. When handling, care should also be taken to prevent leakage caused by damaged packaging. If there is any leakage, it should be dealt with promptly according to the emergency plan to prevent endangering the environment and personal safety.
The third is packaging and labeling. Packaging materials must have good corrosion resistance and sealing, and meet the requirements of relevant standards to ensure that they are intact during storage and transportation. Key information such as the name, content, and hazard signs of the substance should be clearly marked on the outside of the package for easy identification and management. During transportation, follow the regulations on the transportation of hazardous chemicals, and choose suitable transportation tools to ensure stable transportation.
In this way, the quality and safety of 2-% methylfuranone can be guaranteed during storage and transportation, and accidents and losses can be avoided.