2-Iodo-5-methylthiophene

2-Iodine-5-methylthiophene has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Because its molecular structure contains iodine atoms and methylthiophene groups, it imparts unique reactivity and can participate in various chemical reactions, thereby constructing complex organic molecular structures.
First, in the field of pharmaceutical chemistry, it can be converted into compounds with specific pharmacological activities through a series of chemical reactions, laying the foundation for the development of new drugs. In the process of drug development, organic synthesis is crucial. 2-Iodine-5-methylthiophene, with its special structure, may introduce specific functional groups to meet the needs of drug binding to targets and active expression.
Second, it also has important applications in the field of materials science. It can be used as a starting material for the construction of functional materials. After polymerization or copolymerization with other monomers, materials with unique electrical and optical properties are prepared. For example, the synthesis of polymer materials with specific electrical conductivity or optical response is used in organic electronic devices, such as organic Light Emitting Diodes (OLEDs), organic solar cells, etc. In OLEDs, such materials can be reasonably designed and modified, or the luminous color and efficiency can be adjusted; in organic solar cells, the photoelectric conversion efficiency can be improved.
Third, in the field of fine chemicals, it is used to synthesize high value-added fine chemicals, such as special fragrances, pigments, etc. With its unique structure, it endows products with unique properties and functions to meet the diverse needs of the market for fine chemicals.

2-Iodine-5-methylthiophene is also an organic compound. Its physical properties are worth exploring.
Looking at its properties, it is mostly liquid under normal conditions, but it also varies depending on the surrounding conditions. The color is light yellow, or nearly colorless, clear and transparent, and has a specific odor. It can be identified as organic by smell.
When it comes to the melting point, it is about a certain temperature range. This value varies depending on the preparation method and purity. Generally speaking, it is in a relatively low temperature region, reflecting the characteristics of its intermolecular forces. The boiling point is also a key physical property. Under a specific pressure, it boils and vaporizes at a certain temperature. This temperature is its boiling point, which is related to the energy required for the molecule to break free from the liquid phase.
In terms of solubility, it is quite soluble in organic solvents such as ethanol and ether, because it is similar to each other. Organic solvents have molecular polarities or structures similar to 2-iodine-5-methylthiophene, so the two are miscible and soluble. In solvents with strong polarities and different structures such as water, the solubility is not good, and it is difficult to form a uniform mixing system.
Density is also one of its physical properties. It is slightly heavier than water. It is placed in water and often sinks at the bottom. This is determined by its molecular weight and molecular accumulation mode.
In addition, its volatility cannot be ignored. Although it is not a highly volatile substance, it can be partially vaporized and dissipated in the surrounding space under appropriate temperature and gas flow conditions. This volatility is related to factors such as boiling point and vapor pressure, reflecting its tendency to transition from liquid phase to gas phase.
These physical properties are of great significance in chemical synthesis, separation and purification, and related applications, and are the key basis for chemists to manipulate this substance and play its role.

The synthesis method of 2-iodine-5-methylthiophene, although not directly described in the ancient book "Tiangong Kaiwu", can be deduced from the ancient chemical process ideas, supplemented by today's chemical knowledge.
The ancient method for preparing halogenated aromatics is often based on aromatics, and halogen atoms are introduced by electrophilic substitution. To prepare 2-iodine-5-methylthiophene, 5-methylthiophene can be used as the starting material.
First, the combination of iodine elemental substance and oxidant can be borrowed. Mix an appropriate amount of iodine elemental substance with 5-methylthiophene, and add a mild oxidant such as hydrogen peroxide or nitric acid. The function of the oxidizing agent is to activate the iodine elemental substance and promote its electrophilic substitution with the thiophene ring. During the reaction, the temperature needs to be controlled to prevent excessive reaction and the by-products are clustered. Generally speaking, the low temperature to medium temperature range is more suitable, about 0 ° C to 50 ° C. In this process, the iodine atom selectively replaces the hydrogen atom at the 2-position of the thiophene ring to obtain the target product 2-iodine-5-methylthiophene.
Second, the method of metal catalysis can be adopted. Metal catalysts such as palladium acetate or cuprous iodide are used as aids. First, the metal catalyst is complexed with the ligand to enhance its catalytic activity. After that, 5-methylthiophene, iodine source (such as iodine substitution reagent) and metal catalyst system are co-placed in a suitable solvent, such as N, N-dimethylformamide or dichloromethane. Under the protection of appropriate temperature and inert gas, the metal catalyst prompts the substitution reaction of iodine atoms with thiophene ring to realize the synthesis of 2-iodine-5-methylthiophene. The key to this method lies in the fine regulation of catalysts, ligands and reaction conditions to achieve efficient and highly selective synthesis.
Furthermore, it can be obtained by conversion of other iodine-containing intermediates. Compounds containing iodine with appropriate functional groups are first synthesized, and then converted into 2-iodine-5-methylthiophene through functional group conversion. For example, esters or halogenated hydrocarbons containing iodine and connected to thiophene rings are first prepared, and then the structure of the target product is gradually constructed through reaction steps such as hydrolysis and elimination. This approach requires careful control of the conditions and selectivity of each step of the reaction to successfully achieve the synthesis of 2-iodine-5-methylthiophene.

2-Iodine-5-methylthiophene is an important raw material in organic synthesis. During storage and transportation, many key matters need to be paid attention to to to ensure its quality and safety.
Bear the brunt, and the storage environment must be cool and dry. This compound is susceptible to moisture, and humid environments may cause it to undergo chemical reactions, resulting in quality deterioration. Therefore, it should be stored in a dry place, away from water sources and steam, and the temperature should be maintained at a low level to prevent it from decomposing or deteriorating due to excessive temperature.
Secondly, it needs to be stored in a dark place. 2-Iodine-5-methylthiophene is more sensitive to light, and light or luminescent chemical reactions affect its chemical stability. Therefore, dark containers should be used when storing, or stored in a warehouse protected from light to reduce the effect of light on it.
Furthermore, when storing this compound, it should be stored separately from oxidants, acids and other substances. Because of its specific chemical properties, contact with these substances, or cause violent chemical reactions, there are serious safety hazards such as explosion or fire. Therefore, it is necessary to strictly follow the chemical storage specifications and arrange the storage location reasonably.
When transporting, do not take it lightly. Make sure that the packaging is intact to prevent leakage during transportation. Packaging materials should have good sealing and corrosion resistance, which can effectively resist the influence of external factors on 2-iodine-5-methylthiophene. Transportation vehicles need to be equipped with corresponding emergency treatment equipment and protective equipment. In the event of an emergency such as leakage, timely response measures can be taken. During transportation, the driving route should try to avoid densely populated areas and environmentally sensitive areas to reduce the harm that may be caused in the event of an accident. In short, the storage and transportation of 2-iodine-5-methylthiophene should be treated with caution to ensure its safety and quality.

What you are inquiring about is the market price of 2-iodine-5-methylthiophene. However, the price of this chemical is difficult to say in a word, and it varies due to many factors.
The first to bear the brunt is the cost of production. The price of raw materials, the production process, and the amount of energy consumption all affect its cost. If raw materials are scarce and expensive, or the production process is complicated, many steps and special equipment are required, or the energy consumption is huge, the cost will be high, and the market price will also rise.
Second, the supply and demand relationship in the market is also the same. If the demand for this product is strong, it is widely used in the pharmaceutical, chemical and other industries, and the supply is limited, when the supply is in short supply, the price will rise. On the contrary, if the demand is weak, the number of manufacturers leads to oversupply, and the price is easy to fall.
Furthermore, the differences in manufacturers also have an impact. Different manufacturers have different technical levels, production scales, and management efficiencies. Those with excellent technology, large scale, and good management may be able to reduce costs, and their product prices may be more competitive; while small factories have higher prices due to cost constraints.
There is a competitive situation in the market. The number and quality of congeneric products or substitutes are all related to price. If there are many alternatives with similar performance and fierce competition, manufacturers may lower prices to attract customers in order to compete for market share.
And the price varies from region to region. Transportation costs, local market consumption levels and policies and regulations are all influencing factors. In remote places, the cost increases due to inconvenient transportation, and the price may be higher than that of convenient transportation; the local consumption level is high, and the price tolerance is strong, and the price may also be different.
As for the specific price, it is difficult to specify exactly. If you want to know the details, you can consult the chemical product trading platform, relevant distributors, or communicate with industry insiders at industry exhibitions and forums to obtain more accurate market price information.