2 Iodo 1 Benzothiophene
quinoline thiophene imidazole thiazole

2-Iodo-1-benzothiophene

Taiy Chemical

    Specifications

    HS Code

    760370

    Chemical Formula C8H5IS
    Molecular Weight 260.095 g/mol
    Appearance Typically a solid (physical state may vary based on conditions)
    Melting Point Data may vary depending on purity, but generally has a defined melting point range
    Boiling Point Appropriate boiling point under specific pressure conditions
    Solubility Solubility characteristics in common organic solvents like ethanol, dichloromethane etc. vary
    Density Specific density value (data may be scarce and need experimental determination)
    Flash Point Flash point relevant for handling safety in presence of ignition sources
    Vapor Pressure Vapor pressure value which is important for volatility assessment
    Stability Stability under normal storage conditions and towards light, heat and air

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    General Information
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    Frequently Asked Questions

    As a leading 2-Iodo-1-benzothiophene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Iodo-1-benzothiophene?
    2-Iodine-1-benzothiophene is also an organic compound. It has a wide range of uses and plays a significant role in the field of organic synthesis.
    First, it can be used as an intermediary for pharmaceutical synthesis. In medical chemistry, it is often necessary to construct molecules with specific structures. The unique structure of 2-iodine-1-benzothiophene can provide a basis for the synthesis of drug molecules with specific physiological activities. Through specific chemical reactions, it can be converted into a key part of the interaction with disease targets, helping to create new drugs to treat various diseases.
    Second, it also has important uses in the field of materials science. It can participate in the preparation of functional organic materials, such as organic semiconductor materials. Due to its structural characteristics, the material is endowed with unique electrical and optical properties, and is expected to be applied to organic Light Emitting Diode (OLED), Organic Field Effect Transistor (OFET) and other devices to improve the performance of such devices, such as enhancing luminous efficiency and improving charge transport capacity.
    Third, it can also play a role in pesticide synthesis. It can be used as a starting material or key intermediate for the synthesis of new pesticides. After chemical modification and transformation, pesticides with efficient control effect on crop diseases and pests can be prepared, and because of its structural particularity, it may reduce the impact on the environment and meet the needs of green agriculture development.
    In conclusion, 2-iodine-1-benzothiophene has important value in many fields such as organic synthesis, medicine, materials and pesticides, and provides key support for the development of related fields.
    What are the physical properties of 2-Iodo-1-benzothiophene?
    2-Iodine-1-benzothiophene is a kind of organic compound. Its physical properties are quite important and are related to the basis of many chemical applications.
    In terms of its appearance, it is often in a solid state, mostly white to light yellow crystalline powder, which is convenient for preliminary identification in experiments and production. Its melting point is about a certain range, due to slight differences in purity, but it is roughly between [specific melting point range]. The property of melting point plays a huge role in the purification and identification of compounds. When you want to know its purity geometry, you can compare it with the standard value by measuring the melting point. If the deviation is small, the purity is high, and if the deviation is large, it may contain more impurities. < Br >
    Furthermore, its solubility also has characteristics. In organic solvents, such as common chloroform, dichloromethane, tetrahydrofuran, etc., it has a certain solubility. This characteristic makes it able to participate in various reactions in these solvent systems in organic synthesis reactions. In water, 2-iodine-1-benzothiophene has extremely low solubility and is almost insoluble. This is because the molecular structure of the compound, benzothiophene ring and iodine atoms are hydrophobic, and the force between them and water molecules is weak, so they are difficult to dissolve in water.
    Its density is also an important physical property, about [specific density value]. This value is indispensable in practical operations such as mass and volume conversion of the compound. For example, when configuring a specific concentration solution, it is necessary to know the density accurately, so that a certain mass of compound can be accurately weighed, and then converted into the corresponding volume according to the density.
    In addition, the stability of 2-iodine-1-benzothiophene is good at room temperature and pressure. However, it should be noted that the iodine atoms in its molecules are relatively active, and under specific conditions, such as high temperature, strong oxidants, etc., they may cause chemical reactions and cause structural changes. Therefore, when storing and using the compound, it is necessary to avoid adverse factors such as high temperature and oxidants, and store it properly to ensure the stability of its chemical properties, thereby ensuring the smooth progress of relevant experiments and production processes.
    What are 2-Iodo-1-benzothiophene synthesis methods?
    The synthesis of 2-iodine-1-benzothiophene involves many approaches in organic chemistry. One method is to use 1-benzothiophene as the starting material and prepare it by halogenation reaction. In this reaction, it is crucial to choose a suitable halogenating agent. Iodine element ($I_ {2} $) is often selected and supplemented with an appropriate oxidizing agent, such as hydrogen peroxide ($H_ {2} O_ {2} $) or nitric acid ($HNO_ {3} $). The cover oxidizing agent can promote the generation of electrophilic iodine cation ($I ^{+}$), from iodine element. Its activity is quite good, and it is easy to undergo electrophilic substitution reaction with the aromatic ring of 1-benzothiophene. For specific operation, dissolve 1-benzothiophene into a suitable organic solvent, such as dichloromethane ($CH_ {2} Cl_ {2} $) or chloroform ($CHCl_ {3} $), slowly add iodine-containing elemental substance and oxidizing agent under cold bath, control the temperature and stir to make the reaction fully proceed. After the reaction, the product is purified by extraction, washing, drying and column chromatography.
    Another synthesis method is to prepare benzothiophene derivatives containing specific substituents first, and then introduce iodine atoms through functional group conversion. For example, benzothiophene with convertible functional groups such as hydroxyl or amino groups can be obtained first, and then iodine atoms can be replaced by diazotization reactions and Sandmeier reactions. Suppose that the 1-benzothiophene derivative containing amino groups is used as the raw material. First, it reacts with sodium nitrite ($NaNO_ {2} $) and acid (such as hydrochloric acid, $HCl $) at low temperature to form a diazonium salt. This diazonium salt is highly active, and then reacts with potassium iodide ($KI $). After the Sandmeier reaction, the amino group is then replaced by an iodine atom to obtain 2-iodine-1-benzothiophene. During operation, the reaction temperature and the amount of each reactant need to be strictly controlled to ensure that the reaction proceeds in the desired direction and improve the yield and purity of the product. And the separation and purification steps after each reaction step are also crucial, which are related to the quality of the final product.
    What is the price of 2-Iodo-1-benzothiophene in the market?
    The price of 2-iodine-1-benzothiophene in the market is difficult to determine. This change in price is related to various reasons.
    First, the situation of supply and demand affects the price. If there are many people in the market, but the supply is small, the price will rise; conversely, if the supply exceeds the demand, the price may drop. Second, the cost of the system is also a major factor. From the purchase of raw materials to the refining process, all costs are involved. The price of raw materials rises, or the cost increases due to changes in the manufacturing process, and the price in the market will also rise accordingly; if the cost is controlled and reduced, the price may fall.
    Furthermore, the price varies depending on the producer. For well-known and skilled producers, the price of their products may be high due to good quality; for emerging or small-scale producers, the market is competitive, and the price may be slightly lower to attract customers. And trade regulations and geographical differences also make prices different. If you buy it from a distance, plus freight, taxes, etc., the price must be higher than nearby.
    Therefore, if you want to know the exact market price of 2-iodine-1-benzothiophene, you should consider the situation in detail, or consult chemical manufacturers, or check the trading platform, to get a near-real price.
    What are 2-Iodo-1-benzothiophene storage conditions?
    2-Iodine-1-benzothiophene is an organic compound. Its storage conditions are crucial and related to the stability and quality of this substance.
    This substance should be stored in a cool, dry and well-ventilated place. If it is cool, avoid the harm of high temperature. High temperature can easily accelerate its chemical reaction, or cause the risk of decomposition and deterioration. Therefore, the temperature should be controlled in a lower range, generally speaking, it is better not to exceed 25 degrees Celsius.
    A dry environment is also indispensable. Moisture can easily cause many adverse reactions, or hydrolyze the compound, or promote other chemical changes with water, damaging its purity and properties. Therefore, in the storage place, when there are good moisture-proof measures, a desiccant can be placed next to it to absorb moisture.
    Well ventilated, it can remove volatile gases that may accumulate. This compound may be volatile. If the gas accumulates, it will increase the risk of explosion and fire, and it will affect the purity of the storage environment, which will then harm the compound itself.
    In addition, the storage place should be away from fire, heat sources and oxidants. Fire and heat sources can cause a sudden rise in temperature and cause danger; oxidants are prone to oxidation reactions with 2-iodine-1-benzothiophene, changing its chemical structure and properties.
    And this substance should be sealed and stored to avoid excessive contact with air. Oxygen, carbon dioxide and other components in the air may react with it. The sealed device can ensure that it is not disturbed by external gases and is stable in the long term.
    In summary, in order to properly store 2-iodine-1-benzothiophene, it is necessary to create a cool, dry and ventilated environment, avoid fire, heat sources and oxidants, and tightly seal it to ensure its quality and stability.