2-((Ethoxycarbonyl)amino)-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylic acid ethyl ester

This compound is called 2- ((ethoxycarbonyl) amino) -4 -methyl-5- (4-nitrophenyl) thiophene-3-carboxylic acid ethyl ester. Its chemical structure is analyzed as follows:
The core of this compound is a thiophene ring, and at position 2 of the thiophene ring, a ((ethoxycarbonyl) amino) group is connected. The so-called ethoxycarbonyl group, that is, -COOCH -2 CH, is then connected to the amino group to form a -NHCOOCH -2 CH 🥰 structure, thereby connecting to the thiophene ring at position 2.
The 4th position of the thiophene ring is methyl (-CH 🥰). Position 5 is connected to a 4-nitrophenyl group, and the para-position (position 4) of this phenyl group has a nitro group (-NO 2), that is, the -C H NO 2 structure is connected to the position 5 of the thiophene ring.
Position 3 of the thiophene ring is connected to the ethyl carboxylate group, that is, -COOCH < CH
In summary, the compound is composed of a thiophene ring as the core and connects specific substituents at different positions, and each substituent gives its unique chemical properties and reactivity.

This compound is called 2 - ((ethoxycarbonyl) amino) -4 -methyl-5- (4 -nitrophenyl) thiophene-3 -carboxylic acid ethyl ester. Its physical properties are as follows:
This compound is mostly solid under normal conditions, due to the existence of various forces between molecules, such as van der Waals force, hydrogen bond, etc., so that its molecules are arranged in an orderly manner to form a relatively stable lattice structure.
In terms of melting point, due to the interaction of various groups in the molecule, including ethoxycarbonyl, nitrophenyl, etc., the intermolecular force is increased and the structural stability is improved, resulting in a high melting point, which is measured experimentally or theoretically calculated to be about [X] ° C. < Br >
In terms of solubility, considering that it contains polar groups such as ethoxy, carbonyl, and nitro, as well as non-polar parts such as methyl and phenyl, it belongs to polar organic compounds. In polar organic solvents such as ethanol and acetone, the solubility is good due to the formation of hydrogen bonds or dipole-dipole interactions with solvent molecules; in non-polar solvents such as n-hexane, due to large polar differences, the solubility is poor; in water, although it contains polar groups, the overall hydrophobicity is strong and the solubility is very small.
Appearance may be white to light yellow powder, which is related to the absorption and scattering characteristics of light by its molecular structure. The conjugate system and chromophore in the molecule absorb light at specific wavelengths, causing it to exhibit corresponding colors.
This compound has a higher density than water, which is due to its tight molecular structure, a large number of atomic types and quantities, and a large mass per unit volume. And in terms of stability, it is relatively stable under general conditions, but under extreme conditions such as strong acids, strong bases or high temperatures and strong oxidants, some chemical bonds in the molecule, such as ester bonds, amino bonds, etc., may undergo hydrolysis and oxidation reactions, resulting in structural changes.

2-%28%28Ethoxycarbonyl%29amino%29-4-methyl-5-%284-nitrophenyl%29thiophene-3-carboxylic acid ethyl ester is an organic compound with a specific chemical structure. This compound has a wide range of uses in the field of organic synthesis.
First, it is often regarded as a key intermediate in pharmaceutical chemistry research. Due to its unique structure, it can be chemically modified to derive a variety of compounds with potential biological activities. By adjusting its substituents, researchers hope to create drug molecules with high affinity and selectivity for specific disease targets, providing opportunities for new drug development. For example, for some disease-related proteins or receptors, the structure of this compound can be modified, or drugs can be obtained that can precisely act on the target, thereby improving the therapeutic effect and reducing side effects.
Second, in the field of materials science, this compound also has application potential. Because it contains specific functional groups, or can participate in polymerization reactions or self-assembly processes, functional materials with special properties can be constructed. For example, materials with photoelectric activity can be prepared for organic Light Emitting Diode (OLED), solar cells and other devices, providing new paths for material performance optimization.
Third, as a model compound of organic synthetic chemistry, the study of its synthesis method is of great significance to the development of organic synthesis methodology. Chemists can use this to explore new reaction paths, optimize reaction conditions, improve the efficiency and selectivity of organic synthesis, and promote the continuous progress of organic synthesis chemistry.

To prepare 2 - (ethoxycarbonyl) amino) -4 - methyl-5 - (4 - nitrophenyl) thiophene-3 - carboxylic acid ethyl ester, the method is as follows:
First, all raw materials need to be prepared, including thiophene compounds containing specific structures, ethoxycarbonylation reagents, nitrification reagents and esterification reagents, etc., and the purity and quality of each raw material need to meet the requirements of the reaction.
At the beginning of the reaction, thiophene compounds are used as the basis, and the ethoxycarbonylation reagent is co-placed in a reaction kettle at a suitable temperature, accompanied by a suitable catalyst, so that the two react. Over time, ethoxycarbonyl amino groups may be introduced at specific positions on the thiophene ring. In this process, temperature, reaction time and catalyst dosage are all key and need to be carefully regulated. If the temperature is too high, side reactions may occur; if the temperature is too low, the reaction will be delayed and the product yield may decrease.
Next, a nitrifying reagent is added to the above reaction system to introduce nitro groups into the phenyl groups connected to the thiophene ring. This step also requires strict control of reaction conditions, such as reaction temperature, drip acceleration of nitrifying reagents, etc. Due to the introduction of nitro groups, the activity and structure of the product are changed, and the slight difference in reaction conditions or the yield and purity of the product are different.
Then, the product of the first two steps of the reaction is reacted with the esterification reagent under specific conditions to form the ethyl ester structure of the target product. This step may require the participation of dehydrating agents, acid binding agents and other additives to promote the forward progress of the reaction, and it is necessary to pay attention to the pH, temperature and time of the reaction system.
After each step of the reaction, the product needs to be separated and purified by suitable methods, such as extraction, distillation, recrystallization, etc., to remove impurities and increase the purity of the product. Through multi-step reaction, separation and purification, relatively pure 2 - ((ethoxycarbonyl) amino) -4 -methyl-5- (4 -nitrophenyl) thiophene-3 -carboxylic acid ethyl ester can be obtained. However, the whole synthesis process is complicated, and the reaction conditions of each step need to be carefully grasped before the ideal results can be obtained.

2-%28%28Ethoxycarbonyl%29amino%29-4-methyl-5-%284-nitrophenyl%29thiophene-3-carboxylic acid ethyl ester, this is the name of organic compound, the Chinese translation is roughly 2 - ((ethoxycarbonyl) amino) - 4 - methyl - 5 - (4 - nitrophenyl) thiophene - 3 - carboxylic acid ethyl ester.
Looking at this compound, it may have potential applications in chemical synthesis, pharmaceutical research and development and other fields. In chemical synthesis, such thiophene derivatives are often important intermediates, which can be derived through various chemical reactions. Compounds with more complex structures and more specific functions can meet the needs of different industrial production.
As for the field of pharmaceutical research and development, thiophene compounds often exhibit a wide range of biological activities, such as antibacterial, anti-inflammatory, and anti-tumor, due to their unique chemical structures and electronic properties. The specific functional groups of this compound, such as nitrophenyl and ethoxycarbonyl, may endow it with specific pharmacological activities. However, in order to truly apply it in drug development, many complicated research steps are still needed.
Initially, in-vitro studies need to be carried out in the laboratory to clarify its mechanism of action, activity intensity, and potential toxicity to specific cell lines. Then, animal experiments are carried out to evaluate its pharmacokinetic properties in vivo, such as absorption, distribution, metabolism and excretion, and to further observe its impact on animal physiology to confirm its safety and effectiveness.
In the current market, although no mature products with this exact compound as the core are widely circulated, in view of the prominent position of thiophene compounds in the chemical and pharmaceutical fields, the research enthusiasm for them has not decreased. Many scientific research institutions and enterprises are continuing to invest resources to explore its potential application value and optimize the synthesis path. With time, with the deepening of research, this compound may emerge in specific fields, give rise to innovative products, and inject new vitality into the development of related industries.