2 Chlorothiophene 5 Formicacid
quinoline thiophene imidazole thiazole

2-Chlorothiophene-5-formicacid

Taiy Chemical

    Specifications

    HS Code

    504265

    Name 2-Chlorothiophene-5-formic acid
    Chemical Formula C5H3ClO2S
    Molar Mass 162.599 g/mol
    Appearance Solid (usually white or off - white)
    Melting Point 140 - 144 °C
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO, DMF
    Pka Value Around 2.9 - 3.1 (approximate value for carboxylic acid group)
    Odor Typically has a faint, organic odor
    Stability Stable under normal conditions but can react with strong oxidizing and reducing agents

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    Frequently Asked Questions

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    What are the physical properties of 2-chlorothiophene-5-carboxylic acid?
    The physical properties of 2-% cyanic acid-5-acetic acid are as follows:
    cyanic acid, its taste is similar to that of bitter almonds, and under normal conditions, it is a transparent liquid with a low boiling temperature and a temperature of 25.7 ° C, which is easy to form. This is because the molecular force is weak, especially the dispersion force is very small, and the effect is also limited, resulting in a boiling temperature to improve. Its melting temperature is -13.2 ° C, and the density is slightly smaller than that of water, < 0.69g/cm ³. Cyanic acid is easily soluble in water, ethanol, ether, etc. Because its molecules can form water, the principle of similar miscibility also promotes its good solubility in water. However, cyanic acid is toxic. Inhaling a small amount of steam or eating a small amount of liquid can cause poisoning and even death. This can inhibit the activity of cytochrome oxidase and block the biological oxidation process, so that the cytochrome method uses oxygen, which can lead to asphyxiation.
    As for acetic acid and common acetic acid, the liquid with a strong and irritating taste is often colored under water, boiling at 117.9 ° C and melting at 16.6 ° C. Because its molecules can form water, the molecular force increases, so the boiling phase is high; and melting water can also solidify ice at a slightly lower temperature due to the molecular force, so it is glacial acetic acid. The density of acetic acid is 1.0492g/cm ³, which is slightly larger than that of water, and it can be miscible in water in any ratio. This is because its carboxyl group can form multiple water molecules, and its molecular properties are also similar to that of water, which is consistent with similar miscibility. In addition, acetic acid has good properties, but some of its low-boiling properties are slightly weaker, because the molecular action limits the escape of molecules to a certain extent.
    What are the chemical properties of 2-chlorothiophene-5-carboxylic acid?
    2-% cyanic acid-5-acetic acid is a common chemical compound, and its chemical properties have been investigated.
    Cyanic acid, toxic and toxic, is toxic, and is often used as a chemical or an aqueous solution. Its molecule is composed of three elements, carbon and nitrogen, and is of the type HCN. Cyanic acid is acidic and weakly acidic. However, under certain conditions, it can be neutralized and reacted to generate cyanide. In addition, three atoms of carbon and nitrogen in cyanic acid make it have a certain reactive activity, which can be reacted to by adding and reacting to other polymers.
    As for acetic acid, also known as acetic acid, it has a mono-acid. It has the general property of acid, and can be reacted to gold and nitrogen, and can be produced. For example, it can be reacted to form acetic acid. It can also neutralize and reverse the production of acetic acid to produce acetic acid water. Acetic acid can be esterified and reversed by alcohol. Under the catalysis of sulfuric acid, ethanol can reverse the production of ethyl acetate water. This reaction is often used in the synthesis of fragrances and solvents. In addition, acetic acid has a harsh and irritating taste. The product solidifies at 16.6 ° C, which is lower than this degree. It solidifies into ice crystals, so it is glacial acetic acid.
    Therefore, 2-% cyanic acid-5-acetic acid has its own unique properties. It plays an important role in chemical research, industrial and biological research, and daily life. However, the use of cyanic acid must be careful because of its toxicity to prevent accidental production.
    What are the main uses of 2-chlorothiophene-5-carboxylic acid?
    The main use of 2-% cyanic acid-5-acetic acid has its important effect in many fields.
    cyanic acid is used in the production of nitrile compounds. Nitrile is an important part of the synthesis, and can be obtained by the reaction of cyanoalkylene, alkylene, etc. This nitrile can be used for the synthesis of nitrile, such as nitrile, which has good warmth retention and light resistance, and is used in the production of water. In addition, cyanic acid can be used in the production of water. The synthesis of certain bacteria and bacteria is used for the purpose of preventing and controlling crop diseases and ensuring the harvest. However, cyanic acid poison should be used with caution and safety.
    As for acetic acid, its use is also very important. In the food industry, acetic acid is the main component of vinegar, which gives vinegar its special sour taste and can be used to taste and enrich the taste of food. In the chemical industry, acetic acid can be used as a solution, because it can dissolve many kinds of compounds, helping to synthesize and reverse. And acetic acid can be used to form important compounds such as acetic anhydride and ethyl acetate. The important acetylation of acetic anhydride is commonly used in ingredients, fragrances, etc.; ethyl acetate has a fragrant taste and is often used as a fragrance and solution, and is widely used in ingredients, inks, etc. In addition, in the industrial field, acetic acid can be used to make certain substances, which is helpful in the treatment of diseases.
    What are the synthesis methods of 2-chlorothiophene-5-carboxylic acid?
    To prepare 2-cyanoacetic acid-5-methyl ester, there are many methods. First, it can be obtained by esterification of cyanoacetic acid and methanol. This reaction requires concentrated sulfuric acid as a catalyst. At a suitable temperature, the carboxyl group of cyanoacetic acid and the hydroxyl group of methanol are dehydrated and condensed to form 2-cyanoacetic acid-5-methyl ester. However, concentrated sulfuric acid is highly corrosive, and the operation needs to be double cautious, and the follow-up treatment is complicated. Neutralization, washing and other steps are required to remove the catalyst and by-products.
    Second, the halogenated acetate is reacted with sodium cyanide. The halogen atom of halogenated acetate is highly active, and the cyanyl group in sodium cyanide can replace the halogen atom to form the target product. In this process, the choice of solvent is very critical, and polar aprotic solvents such as dimethyl sulfoxide are commonly used to promote the reaction. However, sodium cyanide is highly toxic, and safety procedures must be strictly followed during operation to prevent poisoning accidents.
    Third, the method of nitrile hydrolysis and re-esterification can be used. First hydrolyze the cyanide-containing compound into carboxylic acid, and then esterify it with methanol. The hydrolysis step requires acid or base catalysis. If acid catalysis is used, the reaction conditions are relatively mild; if alkali catalysis is used, the reaction speed is faster, but subsequent acidification treatment is required. When esterification, a suitable catalyst is also required to obtain it efficiently < Br >
    The methods for preparing 2-cyanoacetic acid-5-methyl ester have their own advantages and disadvantages. In practice, when considering the availability of raw materials, cost, safety and many other factors, the reaction path is carefully planned, and the synthesis goal is achieved efficiently and safely.
    What are the precautions for 2-chlorothiophene-5-carboxylic acid in storage and transportation?
    2-% amidazole-5-acetic acid is a chemical substance. It is important to pay attention to the general situation when it is in storage.
    First, the storage environment. It needs to be placed in a dry, clean and well-functioning environment, and must not be exposed to sunlight. Due to sunlight exposure or chemical modification, or decomposition and other adverse reactions. And to the source of ignition and heat, this substance may have a certain flammability or sensitivity, and it is easy to be dangerous in case of open flame and high temperature.
    In addition, it is necessary to pay attention to the separation of other substances. 2-% amidazole-5-acetic acid should not be combined with oxidizing substances and other substances. Due to oxidizing substances or chemical and biological reactions, it is caused to malfunction; and chemical substances may also be caused by acetic acid reactions, affecting the quality of their products.

    It is necessary to use suitable packaging materials to ensure a good seal to prevent leakage. If it is a liquid, the packaging container can withstand a certain amount of force to prevent the container from breaking due to shock, collision, etc. during the transportation. And it also needs to comply with the phase safety standards, with fire protection, explosion protection, etc.
    It is also subject to cultivation. Familiar with the characteristics, hazards and emergency treatment methods of 2-% amidazole-5-acetic acid. Invest regularly. If the package is broken, leaks, etc., immediately take appropriate measures, such as isolation, cleaning, and clearance, to ensure human safety and environmental risk. Therefore, whether it is still in existence or 2-% amidazole-5-acetic acid, it is necessary to follow the corresponding operating procedures, and must not be negligent.