2 Chloromethylthiophene
quinoline thiophene imidazole thiazole

2-chloromethylThiophene

Taiy Chemical

    Specifications

    HS Code

    649008

    Chemical Formula C5H5ClS
    Molecular Weight 132.61
    Appearance Colorless to light yellow liquid
    Boiling Point 190 - 192 °C
    Melting Point N/A
    Density 1.26 g/cm³
    Flash Point 76 °C
    Solubility Slightly soluble in water, soluble in organic solvents
    Odor Characteristic odor
    Stability Stable under normal conditions

    As an accredited 2-chloromethylThiophene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing
    Storage
    Shipping
    Free Quote

    Competitive 2-chloromethylThiophene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615365036030 or mail to info@alchemist-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615365036030

    Email: info@alchemist-chem.com

    General Information
    Where to Buy 2-chloromethylThiophene in China?
    As a trusted 2-chloromethylThiophene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 2-chloromethylThiophene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-chloromethylthiophene?
    2-% cyanoethyl sulfoacetic acid is a crucial raw material in the field of organic synthesis. Its main uses are as follows:
    First, it is an indispensable key intermediate in the synthesis of reactive dyes. Reactive dyes are widely used in the textile printing and dyeing industry due to their bright color and good dyeing fastness. 2-% cyanoethyl sulfoacetic acid can introduce specific reactive groups through a series of chemical reactions, so that the dyes can covalently bind with fiber molecules, greatly improving the dyeing effect. Such as the common vinyl sulfone reactive dyes, 2-% cyanoethyl sulfoacetic acid plays a key role in its synthesis process, giving the dyes good reactivity and color fixing properties, ensuring uniform and long-lasting dyeing of fabrics.
    Second, it also plays an important role in the field of pharmaceutical synthesis. The synthesis of some compounds with special pharmacological activities requires the use of 2-% cyanoethyl sulfoacetic acid to build specific molecular structures. For example, in the development and production of some anti-tumor drugs and antibacterial drugs, through the rational use of 2-% cyanoethyl sulfoacetic acid, molecules with specific biological activities can be precisely designed and synthesized, providing strong support for human health.
    Third, in the study of organic synthetic chemistry, as an important synthetic block. Chemists can use various organic reactions to transform and modify them according to their structural characteristics to construct more complex and diverse organic compounds, providing material basis and research direction for the research and development of new materials and the total synthesis of natural products. With its unique chemical properties, 2-% cyanoethyl sulfone acetic acid plays an irreplaceable role in the stage of organic synthetic chemistry, promoting the continuous development of this field.
    What are the synthesis methods of 2-chloromethylthiophene?
    The synthesis of 2-% chloroethyl sulfonyl ethyl ester is related to the technology of organic synthesis. There are many methods, each with its own ingenuity. The following are several common methods:
    First, halogenated alcohols and sulfinates are used as raw materials. Halogenated alcohols, such as 2-chloroethanol, sulfinates such as sodium ethanesulfonate. Under appropriate reaction conditions, such as in polar solvents, heat and catalyze with a specific catalyst. Polar solvents can assist in the dissolution and reaction of ions, and catalysts can reduce the activation energy of the reaction and speed up the reaction rate. In this reaction, the halogen atom of the halogenated alcohol is replaced by the sulfonate of the sulfite salt through the nucleophilic substitution mechanism, resulting in the formation of 2-chloroethyl sulfonyl ethyl ester.
    Second, vinyl sulfone derivatives react with halogenated alkanes. Ethylene sulfone derivatives have active carbon-carbon double bonds, and halogenated alkanes such as chloroethane. Under basic conditions, basic substances can promote the activation of the double bonds of vinyl sulfone derivatives, enhance their nucleophilicity, and then undergo nucleophilic substitution reactions with halogenated alkanes. Factors such as the strength of basic substances, reaction temperature and time all have important effects on the reaction yield and selectivity. Through fine regulation of these conditions, the reaction can proceed smoothly in the direction of generating the target product 2-chloroethyl sulfonyl ethyl ester.
    Third, mercaptan and halogenated esters are used as starting materials. Mercaptan such as ethyl mercaptan, halogenated esters such as ethyl chloroacetate. Under the action of basic catalysts, sulfhydryl anions of mercaptan act as nucleophiles to attack the carbonyl α-carbon of halogenated esters and undergo nucleophilic substitution reactions. During the reaction process, attention should be paid to controlling the pH and temperature of the reaction system to avoid side reactions such as self-oxidation of thiols and hydrolysis of halogenated esters. Efficient synthesis of 2-chloroethyl sulfonyl ethyl ester can be achieved through rational selection of reaction solvent and precise control of reaction conditions.
    These synthesis methods have their own advantages and disadvantages, and the most suitable method should be selected according to the actual situation, such as the availability of raw materials, cost, product purity requirements and other factors.
    What are the physical properties of 2-chloromethylthiophene?
    2-% chlorobenzyl chloride, is an organic compound. Its physical properties are particularly important, related to application and disposal.
    This substance is a colorless to slightly yellow liquid at room temperature. Looking at its shape, it is clear and has a certain fluidity. Smell, there is a pungent smell, this smell is strong, easy to detect, warning it is potentially harmful, and careful protection is required when exposed.
    When talking about the boiling point, it is about 220-225 ° C. The boiling point is quite high, indicating that more heat is required to change it from liquid to gas. This property is crucial in chemical operations such as distillation and separation. < Br >
    Its melting point is relatively low, about -16 ° C. The lower melting point causes it to exist in a liquid state at room temperature. This property also affects its storage and transportation, and it is necessary to prevent solidification at low temperatures, which affects the use.
    2% chlorobenzyl chloride has a higher density than water, about 1.26g/cm ³. When mixed with water, it can be seen that it sinks underwater. This property can be used when the mixture is separated.
    In terms of solubility, it is slightly soluble in water, but easily soluble in a variety of organic solvents, such as ethanol, ether, benzene, etc. This difference in solubility is of great significance in organic synthesis, extraction and other processes. Organic reactions often need to be carried out in a specific solvent system, and its solubility in organic solvents provides a suitable environment for the reaction to help the reaction occur smoothly.
    In summary, the physical properties of 2-% chlorobenzyl chloride, including morphology, odor, melting point, density, solubility, etc., are all useful in chemical industry, scientific research and other fields. Only by knowing its properties can it be used safely and efficiently.
    What are the chemical properties of 2-chloromethylthiophene?
    2-% cyanoethylurea is one of the organic compounds. Its properties have several characteristics.
    The appearance of this substance is often white crystalline, and the color is normal when it is pure. In terms of solubility, it can be slightly soluble in water, but it has better solubility in some organic solvents, such as ethanol and acetone. This solubility makes it an excellent reaction medium in many organic synthesis reactions, helping the reactants to blend with each other and promoting the smooth progress of the reaction.
    In terms of chemical activity, the presence of cyanoethyl in 2-% cyanoethylurea gives it a unique reactivity. Cyanyl (-CN) is a strong electron-absorbing group, which can reduce the electron cloud density of the carbon atoms connected to it, thereby making the carbon atoms more vulnerable to nucleophilic reagents in the process of nucleophilic substitution reactions. In such reactions, cyanoethyl can participate in the formation of new carbon-carbon bonds, carbon-nitrogen bonds, etc., providing the possibility for the construction of complex organic molecular structures.
    And its urea group part is also reactive and can participate in condensation reactions such as. Under suitable conditions, the hydrogen on the nitrogen atom in the urea group can be replaced and react with other compounds containing active groups to form compounds with novel structures. This is of great significance in the fields of drug synthesis and materials science. By ingeniously designing reactions, new materials or potential drug molecules with specific properties can be prepared.
    Furthermore, the stability of 2-% cyanoethylurea is acceptable under moderate conditions. However, in the case of extreme environments such as strong acids, strong bases or high temperatures, its structure may be damaged, and reactions such as hydrolysis and decomposition will occur. During hydrolysis, the cyano group may be converted into a carboxyl group, and the urea group may be broken to form corresponding amines and carboxylic acids. This property also warns that when storing and using the substance, it is necessary to choose a suitable environment to avoid its deterioration and maintain the stability of its chemical properties.
    What should be paid attention to when storing and transporting 2-chloromethylthiophene?
    When storing and transporting 2-% cyanoethyl sulfonyl acetamide, there are many key things to pay attention to. This is an important chemical in fine chemicals, and the first environmental conditions for storage. It should be placed in a cool, dry and well-ventilated place, away from direct sunlight and high temperature environments. Due to its chemical properties, it may be unstable at high temperatures, causing deterioration or posing safety risks. For example, high temperatures may change the molecular structure and reduce product quality.
    Furthermore, the storage area should be kept away from fire, heat sources and oxidants. 2-% cyanoethyl sulfonyl acetamide may react violently with oxidants, resulting in fire or explosion accidents. And should be stored separately from acids, alkalis and other chemicals to avoid mixed storage to prevent chemical reactions.
    Storage containers are also crucial, and appropriate materials must be selected. Usually, use corrosion-resistant containers, such as specific plastic materials or stainless steel containers, to prevent the container from reacting with chemicals and affecting product quality.
    In terms of transportation, relevant regulations and standards must be strictly followed. Transportation vehicles need to be equipped with corresponding safety equipment, such as fire extinguishers, leakage emergency treatment tools, etc. And during transportation, ensure that the packaging is intact to prevent chemical leakage. In the event of a leak, effective emergency measures need to be taken in a timely manner, such as evacuating personnel, sealing off the scene, and properly disposing of the leak.
    When loading and unloading, the operator should handle it with care to avoid collision and dragging to prevent package damage. In short, the storage and transportation of 2-% cyanoethyl sulfonyl acetamide must be treated with caution, follow the specifications, and ensure the safety of personnel and product quality.