2 Bromo 3 Methylthiophene
quinoline thiophene imidazole thiazole

2-Bromo-3-methylthiophene

Taiy Chemical

    Specifications

    HS Code

    689905

    Chemical Formula C5H5BrS
    Molecular Weight 179.062 g/mol
    Appearance A colorless to pale yellow liquid
    Boiling Point 202 - 204 °C
    Melting Point N/A
    Density 1.625 g/cm³
    Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
    Flash Point 82 °C
    Odor Characteristic sulfur - containing odor
    Cas Number 54276 - 51 - 0

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    General Information
    Where to Buy 2-Bromo-3-methylthiophene in China?
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    Frequently Asked Questions

    As a leading 2-Bromo-3-methylthiophene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-bromo-3-methylthiophene?
    2-% arsine-3-methylindole is an important raw material for organic synthesis. In the field of medicinal chemistry, its use is quite critical. It can be used as a key intermediate to synthesize many biologically active drug molecules. For example, when developing specific anti-cancer drugs, the unique chemical structure of 2-% arsine-3-methylindole can give drug molecules the ability to target specific cancer cells, help improve drug efficacy, and reduce damage to normal cells.
    In the field of materials science, it also has applications. Due to its stable chemical properties, it can participate in the synthesis of organic materials with special functions. For example, the preparation of materials with excellent photoelectric properties can be used in optoelectronic devices such as organic Light Emitting Diode (OLED). This kind of material can make the OLED screen show more vivid color gamut and higher contrast, and improve the display effect.
    In addition, in the field of dye chemistry, 2-% arsine-3-methylindole can be used as the basic raw material for synthesizing new dyes. With the modification and modification of its structure, dyes with special color, light resistance and stability can be obtained. Applied to the textile printing and dyeing industry, it can make the fabric dyeing more uniform, firm, and lasting bright color. In short, 2-% arsine-3-methylindole plays an indispensable role in many important fields and is of great significance to the development of related industries.
    What are the synthesis methods of 2-bromo-3-methylthiophene?
    To prepare 2-bromo-3-methylbutane, the following methods can be adopted.
    First, 3-methyl-1-butene is used as a raw material and is added to hydrogen bromide. According to the Markov rule, hydrogen is added to the double-bonded carbon containing more hydrogen, and bromine is added to the double-bonded carbon containing less hydrogen to obtain the target product. The reaction is: 3-methyl-1-butene reacts with hydrogen bromide under appropriate conditions, the double bond is opened, the bromine atom is connected to the No. 2 carbon, and the hydrogen atom is connected to the No. 1 carbon to generate 2-bromo-3-methylbutane.
    Second, 3-methyl-2-butanol is used as the raw material. First, 3-methyl-2-butanol undergoes a substitution reaction with hydrobromic acid, and the hydroxyl group of the alcohol is replaced by a bromine atom. During the reaction, the hydroxyl group in the alcohol is combined with the hydrogen in the hydrobromic acid to form water, and the bromide ion replaces the hydroxyl group position to obtain 2-bromo-3-methylbutane.
    Third, 3-methylbutane is used as the raw material and undergoes a free radical substitution reaction with bromine under the condition of light. Due to the different stability of free radicals, the probability of substitution of secondary hydrogen is higher than that of primary hydrogen. Although there will be a variety of substitution products, the proportion of 2-bromo-3-methylbutane can be increased by controlling the reaction conditions and the proportion of raw materials. During the reaction, bromine molecules are uniformly split into bromine radicals under light, and bromine radicals capture hydrogen atoms in 3-methylbutane molecules to form new radicals. The new radicals then react with bromine molecules to generate 2-bromo-3-methylbutane and other products.
    These methods have their own advantages and disadvantages. In actual synthesis, it is necessary to comprehensively consider various factors such as the availability of raw materials, the ease of control of reaction conditions, and the requirements for product purity, and choose the best one.
    What are the physical properties of 2-bromo-3-methylthiophene?
    2-% ether-3-methylpentane is an organic compound with unique physical properties.
    Looking at its properties, under normal temperature and pressure, 2-% ether-3-methylpentane is mostly a colorless and transparent liquid with a pure texture and no impurities visible to the naked eye. This compound has a specific odor, although not pungent, it is unique and can be easily identified in a specific chemical environment.
    When it comes to the melting boiling point, the boiling point of 2-% ether-3-methylpentane is relatively low, about a certain temperature range. The lower boiling point makes it easy to transform into a gaseous state under relatively mild heating conditions. This property is quite valuable in many chemical experiments and industrial production processes, such as distillation separation. Its melting point is also in a specific low temperature range, so that in a specific low temperature environment, the compound can solidify from liquid to solid.
    When it comes to density, the density of 2-% ether-3-methylpentane is less than that of water, so when it is mixed with water, it will clearly float on the water surface, forming a significant stratification phenomenon. This property provides convenience for separating the mixture of the compound and water.
    In terms of solubility, 2-% ether-3-methylpentane is a non-polar organic solvent. According to the principle of similarity miscibility, it exhibits good solubility to many non-polar or weakly polar organic compounds, such as some oils, waxes and some organic pigments, which can be dissolved in it, so it is widely used in organic synthesis, coating preparation and other fields. However, it has very poor miscibility with polar solvents such as water and is almost difficult to dissolve with each other.
    In terms of volatility, 2-% ether-3-methylpentane has strong volatility and will quickly evaporate into the air in an open environment. On the one hand, this feature makes it possible to apply it in some products that require rapid drying, such as paints and adhesives; on the other hand, due to its high volatility, special attention should be paid to sealing during storage and use to prevent volatile loss and possible safety risks.
    What are the chemical properties of 2-bromo-3-methylthiophene?
    2-% hydroxyl-3-methylglutaric acid, its chemical properties are as follows:
    This substance is acidic, because it contains a carboxyl group (-COOH), it can neutralize with a base. In case of sodium hydroxide, the hydrogen in the carboxyl group dissociates, combines with the hydroxide group to form water, and forms a carboxylate by itself. In the reaction formula: HOOC - CH (OH) -CH (CH) -CH (OH) -COOH + 2NaOH → NaOOC - CH (OH) -CH (CH) -CH (CH) -COONa + 2H 2O O.
    Its hydroxyl group (-OH) is also active. A substitution reaction can occur. When interacted with hydrohalic acids (such as HBr), the hydroxyl group is replaced by a bromine atom to obtain a halogenated hydrocarbon. The reaction is as follows: HOOC - CH (OH) -CH (CH < unk >) -CH < unk > - COOH + HBr → HOOC - CH (Br) -CH (CH < unk >) -CH < unk > - COOH + H < unk > O. At the same time, the hydroxyl group can participate in the esterification reaction, and form esters and water with alcohols under acid catalysis. For example, when reacted with ethanol: HOOC - CH (OH) -CH (CH < unk >) -CH < unk > - COOH + 2C < unk > H < unk > OH $\ underset {\ triangle} {\ overset {concentrated sulfuric acid} {=\! =\!=}}$ C 2O H OOC - CH (OH) -CH (CH
    Due to the presence of multiple carbon-carbon single bonds in the molecule, oxidation reactions can occur. Under suitable oxidizing agents and conditions, the carbon chain may be oxidized and broken, resulting in smaller molecular oxidation products.
    And because its structure contains chiral carbon atoms (carbon with four different atoms or groups), it has optical rotation, which can rotate the vibration plane of polarized light, and there are enantiomers. In vivo or in specific chemical reactions, different enantiomers may exhibit different activities and reaction results.
    What is the price range of 2-bromo-3-methylthiophene in the market?
    In today's market, the price of dibromotrimethylpentane varies depending on the purity of the quality, the quantity, and the state of supply and demand. If its quality is pure and the quantity is low, and the market's demand is also prosperous, the price may be slightly higher; if the quality is miscellaneous, the quantity is small, and the demand is thin, the price will be cheaper.
    Generally speaking, the price of ordinary pure products, measured in kilograms, is about tens of gold to hundreds of gold. If it is a crude product with more impurities, the price may be only half of the pure product, or even less.
    And the origin is different, the price is also different. If the product is close to the city, and the transportation is convenient, the price may be slightly lower, so as to save the cost of transportation; if the place of origin is remote and the transportation is difficult, the price must be high. In addition, the price also changes depending on the time. When the city is in a hurry, although the price is high, people will compete to buy it; when it needs to be delayed, although the price is low, it is not easy to sell it.
    Businesses often set prices according to various conditions, so if you want to know the exact price, you must carefully examine the situation of the city, the quality of the goods, and the state of supply and demand.