2-bromo-1-benzothiophene

2-Bromo-1-benzothiophene, or 2-bromo-1-benzothiophene, has a wide range of uses. In the field of organic synthesis, it is a key intermediate and can be derived from other compounds through various chemical reactions.
In organic synthesis, 2-bromo-1-benzothiophene can be involved in metal-catalyzed coupling reactions. Such as Suzuki coupling reaction, it can form a carbon-carbon bond with aryl boronic acid in the presence of palladium catalyst and base, and obtain a product with biaryl structure. This product is of great significance in the field of materials science and can be used to create organic Light Emitting Diode (OLED) materials. OLEDs have gradually become the mainstream in the development of display technology due to their excellent self-luminescence, high contrast and wide viewing angle. The materials prepared by 2-bromo-1-benzothiophene through this reaction may improve the properties of OLEDs, such as improving luminous efficiency and prolonging service life.
can also participate in the Heck reaction, which reacts with olefins under palladium catalysis to construct products with carbon-carbon double bonds. This product has considerable uses in the field of medicinal chemistry. Many drug molecules contain carbon-carbon double bond structures, and 2-bromo-1-benzothiophene may contribute to the construction of specific drug molecular structures through this reaction, promoting the development of new drugs.
In terms of materials science, 2-bromo-1-benzothiophene can also be used to prepare organic semiconductor materials. Organic semiconductors have attracted much attention in the field of flexible electronic devices due to their flexibility and solution processing properties. 2-bromo-1-benzothiophene can be polymerized and other means to prepare organic semiconductor polymers with specific electrical properties, which can be used in field effect transistors, solar cells and other devices. These flexible electronic devices are expected to realize innovative applications such as wearable devices and smart electronic skins, bringing more convenience and possibility to people's lives. With its unique structure, 2-bromo-1-benzothiophene plays an important role in the fields of organic synthesis and materials science, and has promoted the development of many cutting-edge technologies.

2-Bromo-1-benzothiophene is one of the organic compounds. Its physical properties are crucial and relevant to many chemical applications.
First of all, its appearance, 2-bromo-1-benzothiophene is often in a solid state. This solid state characteristic is different from liquid substances when stored and transported, and specific conditions are required to maintain its stability. Looking at its color, it is mostly white to light yellow. This color feature can help chemists judge its purity and state during preliminary observation.
As for the melting point, this compound has a certain melting point value, which is about a certain range (although the exact value depends on the specific experimental conditions and purity). The determination of the melting point is one of the important means to identify the compound, and the melting point reflects the strength of the intermolecular forces, which is related to the compactness of its crystal structure.
The boiling point is also an important physical property. Under specific pressure conditions, 2-bromo-1-benzothiophene will reach the boiling point and vaporize. Knowing the boiling point is crucial when separating and purifying the substance. Chemists can separate it from the mixture by distillation and other methods according to the difference in boiling points.
In terms of solubility, 2-bromo-1-benzothiophene exhibits specific solubility characteristics in common organic solvents. In some organic solvents such as dichloromethane and chloroform, it has good solubility. This characteristic allows chemists to select suitable solvents during reaction operations to promote the smooth progress of the reaction, or in the extraction process, take advantage of their solubility differences to achieve separation and enrichment of substances.
In addition, the density of 2-bromo-1-benzothiophene also has its specific value. Although this value is not as commonly used as melting point, boiling point and solubility in practical applications, it is also indispensable in specific chemical processes and theoretical calculations.
In summary, the physical properties of 2-bromo-1-benzothiophene, such as appearance, melting point, boiling point, solubility and density, are all factors that chemists must consider in detail when studying and applying this compound. Each property is interrelated and jointly determines its behavior and use in the chemical field.

2-Bromo-1-benzothiophene is also an organic compound. There are several methods for its chemical synthesis.
First, 1-benzothiophene is used as the starting material. Shilling 1-benzothiophene reacts with brominating reagents, such as bromine (Br ²), under appropriate reaction conditions. The reaction needs to be in a suitable solvent, such as dichloromethane and other inert organic solvents, and the reaction temperature needs to be precisely controlled. Generally speaking, the reaction at low temperature can better control the selectivity of the reaction, and it is appropriate to be between 0 ° C and room temperature. During the reaction, bromine atoms will selectively replace the hydrogen atoms at specific locations in 1-benzothiophene to form 2-bromo-1-benzothiophene. However, in this process, side reactions may occur, such as the formation of polybrominated products, so the reaction process needs to be closely monitored, and thin layer chromatography (TLC) can be used.
Second, transition metal catalysis can be used. Transition metal complexes such as palladium (Pd) are used as catalysts, and suitable ligands, such as phosphine ligands, are used. 1-benzothiophene reacts with bromine-containing reagents, such as brominated aryl groups, in the presence of bases. This reaction system is relatively complex, and the type and dosage of catalysts, ligands and bases need to be optimized. Suitable bases, such as potassium carbonate (K ² CO 🥰), can promote the reaction. The advantage of this method is that the reaction conditions are relatively mild and the selectivity is high, which can effectively reduce the occurrence of side reactions.
Third, if benzothiophene derivatives are used as raw materials and transformed into specific functional groups, 2-bromo-1-benzothiophene can also be synthesized. For example, a specific site in a benzothiophene derivative is first functionalized, a group that can be converted into a bromine atom is introduced, and then the group is converted into a bromine atom through a series of reactions to achieve the synthesis of the target product. This method requires careful design of the reaction steps to ensure the smooth progress of each step and the purity of the product.
In short, there are many methods for synthesizing 2-bromo-1-benzothiophene. According to actual needs, the most suitable synthesis method should be selected after considering the availability of raw materials, the difficulty of reaction conditions, the purity and yield of the product, etc.

2-Bromo-1-benzothiophene is one of the organic compounds. In the case of market price, it is difficult to draw a conclusion. The price of bromo-1-benzothiophene is often changed due to multiple factors, and all factors are intertwined, resulting in fluctuations in its valence state.
The first to bear the brunt is the cost of raw materials. The preparation of this compound requires specific starting materials. If the supply of these raw materials in the market is scarce, or due to changes in origin or production blockages, the price of 2-bromo-1-benzothiophene will also rise, which will eventually be reflected in the market price.
Furthermore, the difficulty of the preparation process is closely related to the cost. If the process required to synthesize this compound is complicated, requires high-end equipment, special reaction conditions, or goes through a multi-step reaction and the yield is not high, and consumes a lot of manpower and material resources, the production cost will increase greatly, and the market price will also be high.
The supply and demand situation of the market is also the key. If the demand for 2-bromo-1-benzothiophene is strong in the industry, such as in medicine, materials science and other fields, and the demand is increasing, and the supply is difficult for a while, the price will rise; conversely, if the demand is flat and the supply is abundant, the price will decline.
In addition, the number of manufacturers and the degree of competition also affect its price. There are many manufacturers and fierce competition. In order to compete for market share, there may be price reduction promotions; on the contrary, if there are few manufacturers and they are almost monopolistic, the price may remain high.
Looking at the past market, the trajectory of its price fluctuations can also be used as a reference for today. However, the market is unpredictable, and the past state may not fully predict the present and future. To know the exact market price of 2-bromo-1-benzothiophene, it is necessary to check the latest information such as chemical product trading platforms and supplier quotations in real time, and comprehensively weigh all factors to obtain a more accurate price cognition.

2-Bromo-1-benzothiophene is an important intermediate in organic synthesis and is widely used in many fields such as medicine, pesticides, materials, etc. However, in today's world, I have searched many ancient books, but it is difficult to find an exact record of the manufacturer of this compound. Although this is the case, according to common sense, the manufacturers of such fine chemicals are mostly manufacturers focusing on organic synthetic chemicals.
In today's chemical industry, many large chemical companies and fine chemical companies often have complete R & D and production systems, and are likely to be involved in the production of 2-bromo-1-benzothiophene. For example, some manufacturers that use organic synthesis intermediates as their main products have mature production processes and well-equipped equipment, or can produce high-quality 2-bromo-1-benzothiophene.
Furthermore, in the affiliated enterprises of universities and scientific research institutions, there may also be producers of this compound. Because of its cutting-edge scientific research results and technical support, it is possible to convert scientific research results into actual products. However, due to the lack of information, it is difficult to specify the name of the specific manufacturer. For accurate information, you may need to check the chemical product directory, industry exhibition materials, or consult professionals in the chemical industry to have the opportunity to know the details of the manufacturer of 2-bromo-1-benzothiophene.