2 Amino 4 5 Dimethylthiophene 3 Carboxylic Acid
quinoline thiophene imidazole thiazole

2-Amino-4,5-dimethylthiophene-3-carboxylic acid

Taiy Chemical

    Specifications

    HS Code

    408019

    Name 2-Amino-4,5-dimethylthiophene-3-carboxylic acid
    Molecular Formula C7H9NO2S
    Molecular Weight 171.217 g/mol
    Appearance Solid (likely, common for such organic compounds)
    Physical State At Room Temp Solid
    Solubility In Water Limited solubility (due to the non - polar thiophene and methyl groups)
    Solubility In Organic Solvents Soluble in polar organic solvents like DMSO, DMF
    Boiling Point Decomposes before boiling due to heat - sensitive nature of the structure, no distinct boiling point
    Acidity Pka No general pKa value known without literature search, but carboxylic acid group gives acidic character
    Stability Stable under normal conditions, but sensitive to strong acids, bases and oxidizing agents

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    Frequently Asked Questions

    As a leading 2-Amino-4,5-dimethylthiophene-3-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2-Amino-4, 5-dimethylthiophene-3-carboxylic acid?
    2-Amino-4,5-dimethylthiophene-3-carboxylic acid, this is an organic compound. Looking at its physical properties, it is usually in a solid state at room temperature and pressure. Its melting point is mostly determined by intermolecular forces and lattice structure, but the specific value often varies depending on the preparation method and purity.
    When it comes to solubility, because it has both polar carboxyl and amino groups in the molecule, and relatively non-polar thiophene rings and methyl groups, it may have a certain solubility in polar solvents such as water, but in non-polar organic solvents such as n-hexane, the solubility may be lower. This property is derived from the principle of similar compatibility. Polar molecules are easily soluble in polar solvents, and non-polar molecules are easily soluble in non-polar solvents.
    Furthermore, its appearance may be white to light yellow powdery solid. The formation of this color is related to the absorption and reflection characteristics of the molecular structure to light. The state of powder is also related to its crystallization habit and preparation process.
    Its density is also one of the important physical properties, which is determined by the molecular weight and the degree of molecular packing compactness. Although the exact density value varies according to specific conditions, its overall density may be comparable to that of common organic solids.
    The physical properties of this compound are of great significance in the fields of organic synthesis, medicinal chemistry, etc. Knowing its melting point is helpful to choose an appropriate method in the purification process; knowing its solubility is convenient for the selection of solvents in the reaction system, which in turn affects the reaction rate and yield.
    What are the chemical properties of 2-Amino-4, 5-dimethylthiophene-3-carboxylic acid
    2-Amino-4,5-dimethylthiophene-3-carboxylic acid, this is an organic compound. Its chemical properties are quite unique, let me tell you in detail.
    Looking at its structure, the thiophene ring is the core, and the amino group, carboxyl group and methyl group are all connected to it. This structure gives it special acid-base properties. The carboxyl group is acidic, and under suitable conditions, it can dissociate hydrogen ions, exhibit acidic properties, and can neutralize with bases, just like "yin and yang". The amino group has a certain alkali nature and can interact with acids, which is its acid-base nature.
    Furthermore, its physical properties are also affected by the structure. Due to the presence of polar groups in the molecule, such as carboxyl and amino groups, it may have good solubility in polar solvents, but it may not have good solubility in non-polar solvents, as if "things of a feather".
    Its chemical activity cannot be ignored. Amino groups can participate in many reactions, such as reacting with acylating reagents to form amide compounds, which is the activity of amino groups. Carboxyl groups can also participate in esterification reactions, reacting with alcohols under specific conditions to form esters, which is like "blending with each other to derive new compounds". Although thiophene rings are relatively stable, under appropriate conditions, they can also participate in electrophilic substitution reactions and introduce new groups on the rings, which is their unique reactivity.
    This compound is of great significance in the field of organic synthesis. It can be used as a key intermediate. After various reactions, many compounds with special properties are derived, which is like the key to opening the door of chemical synthesis. It has broad application prospects in drug development, materials science and other fields.
    What is the common synthesis method of 2-Amino-4, 5-dimethylthiophene-3-carboxylic acid?
    The common synthesis methods of 2-amino-4,5-dimethylthiophene-3-carboxylic acid cover a variety of paths. First, the corresponding thiophene derivatives can be initiated. First, take a suitable substituted thiophene, and introduce halogen atoms at a specific position through halogenation. This halogenation process requires careful selection of halogenating reagents and reaction conditions. For example, N-bromosuccinimide (NBS) can be selectively halogenated under appropriate solvents and temperatures.
    Then, the halogenated thiophene and amine compounds undergo nucleophilic substitution. In this step, the control of amine activity and reaction conditions is crucial. Suitable bases and solvents, such as potassium carbonate in DMF solvents, can promote the smooth occurrence of nucleophilic substitution to introduce amino groups.
    Furthermore, for the construction of carboxylic acid moieties. It can be reacted with metal-organic reagents (such as Grignard reagents) by halogenates, and then carboxylated with carbon dioxide. For example, after the halogenated thiophene is made into Grignard reagents, carbon dioxide gas is introduced, and subsequent acidification treatment can obtain carboxylic acid groups.
    Another strategy is to start with the construction of sulfur-containing heterocycles. Using sulfur-containing compounds and unsaturated carbonyl compounds, in the presence of suitable catalysts, the cyclization reaction generates thiophene rings, and the desired substituents are introduced at the same time. Subsequently, amino and carboxylic acid groups are introduced according to the above-mentioned similar methods. During the synthesis process, the purification and separation of each step of the reaction is very critical, and column chromatography, recrystallization and other means are often used to ensure the purity of the product, and then the target 2-amino-4,5-dimethylthiophene-3-carboxylic acid is obtained.
    2-Amino-4, 5-dimethylthiophene-3-carboxylic acid is used in which areas
    2-Amino-4,5-dimethylthiophene-3-carboxylic acid, this substance has its use in various fields. In the field of medicine, it is an important synthetic raw material. Because of its unique chemical structure, it can be used as an intermediate to produce a variety of specific drugs. Based on it, physicians develop prescriptions for the treatment of intractable diseases, such as for certain stubborn diseases, using it to participate in the synthesis of drugs, or it can play a key role in the recovery of patients.
    In the field of materials science, it also has extraordinary value. With it as a component, it may be able to develop new functional materials. These materials may have specific physical and chemical properties, such as excellent conductivity, stability, etc. When used in electronic devices, its performance can be improved, such as making electronic components more efficient and durable, and promoting the progress of electronic technology.
    In the field of organic synthetic chemistry, 2-amino-4,5-dimethylthiophene-3-carboxylic acid is a key building block. Chemists use it to build complex organic molecules and expand the types and structures of organic compounds. Through exquisite reaction design, it can be used as a starting material to synthesize organic molecules with novel structures and unique properties, which contribute to the development of organic chemistry and lay the foundation for subsequent research and application.
    What is the market outlook for 2-Amino-4, 5-dimethylthiophene-3-carboxylic acid?
    2-Amino-4,5-dimethylthiophene-3-carboxylic acid, this is a very important organic compound. It has potential applications in many fields such as chemical industry, medicine, and materials.
    In the chemical industry, it can be used as a key intermediate for the synthesis of multiple complex organic compounds. Through specific chemical reactions, various compounds with different functions can be derived, which play a key role in the preparation of fine chemical products.
    In the pharmaceutical field, due to its unique chemical structure, it may have potential biological activity. Researchers can modify its structure, develop new drugs, or show therapeutic effects for specific diseases, but the current in-depth research on this compound in medicine may still be in its infancy, and clinical application may still need a long time to explore.
    In the field of materials, it may be used to prepare materials with special properties. For example, by compounding with other substances, the material is endowed with unique electrical, optical or mechanical properties, but related applications also need to be further explored and developed.
    In terms of market prospects, with the continuous development of chemical, pharmaceutical and materials industries, the demand for this compound may be increasing. However, due to its research and application still in the expansion stage, the market size has not yet reached a huge level. If key breakthroughs can be made in the fields of medicine and materials in the future, its market potential will be greatly released, and it is expected to become an important basic raw material for related industries, with considerable prospects.