2-Amino-3-cyanothiophene

2-Amino-3-cyanothiophene is a class of organic compounds. It has a wide range of uses and is important in many fields.
In the field of medicinal chemistry, this compound is often a key intermediate for the synthesis of drugs. Due to the unique chemical properties of thiophene ring with amino and cyano groups, it can be chemically modified to construct compounds with diverse structures to be effective against different disease targets. For example, it can be used to create drugs with antibacterial and anti-inflammatory properties. By interacting with bacteria or inflammation-related proteins, it can block their normal physiological functions and achieve the purpose of treating diseases. < Br >
In the field of materials science, 2-amino-3-cyanothiophene also has considerable applications. Due to its conjugated structure, the material is endowed with unique electrical and optical properties. It can be used to prepare organic semiconductor materials and used in organic Light Emitting Diode (OLED), organic field effect transistor (OFET) and other devices. In such devices, it can be used as a carrier transport layer or a light-emitting layer material to improve the luminous efficiency and stability of the device, and provide power for the development of new display and electronic devices.
It also has its uses in pesticide chemistry. It can be used as a raw material to synthesize pesticides with specific biological activities. By modifying its structure, synthetic pesticides can be highly selective and efficient for specific pests or weeds, reduce the impact on non-target organisms in the environment, achieve green and efficient pesticide creation, and ensure crop yield and quality in agricultural production.
In summary, the unique structure of 2-amino-3-cyanothiophene plays an important role in medicine, materials, pesticides and other fields, providing a foundation for technological innovation and development in various fields.

2-Amino-3-cyanothiophene is one of the organic compounds. It has specific physical properties, let me talk about them one by one.
Looking at its properties, at room temperature, it is mostly in a solid state, which is caused by factors such as intermolecular forces. And its texture is relatively stable, and it is difficult to spontaneously produce significant changes in the general environment.
When it comes to the melting point, the melting point is quite high, about a certain temperature value, which reflects the degree of bonding between molecules. The boiling point also needs to be reached below higher temperature conditions, which shows that in order to make it change from liquid to gas state, sufficient energy needs to be supplied to overcome the attractive force between molecules.
In terms of solubility, it has a certain solubility in common organic solvents such as ethanol and acetone. This is due to the appropriate interaction between the molecular structure of the compound and the organic solvent molecules, such as van der Waals forces, hydrogen bonds, etc., which makes it dispersed between solvent molecules. However, the solubility in water is relatively limited, and the interaction between the two is weak due to the poor matching of the polarity of water and the molecular polarity of the compound.
As for the density, it is larger than water. If it is placed in water, it will sink to the bottom, which is determined by its molecular mass and molecular accumulation mode.
In addition, the color state of 2-amino-3-cyanothiophene is usually white to off-white, with pure color and no noise. This appearance characteristic is also part of its physical properties, which is helpful in identifying and judging its purity.

2-Amino-3-cyanothiophene is also an important compound in the field of organic synthesis. Its synthesis method has been explored by many predecessors, and several common methods are listed as follows.
First, the method of using thiophene as the starting material. First, the thiophene is introduced into the thiophene ring through a specific reaction, such as halogenation. After halogenation, the cyanide group is substituted for the halogen atom to obtain a cyanothiophene-containing thiophene derivative. Then, through the amination reaction, the amino group is introduced at a specific position under suitable conditions, and the final result is 2-amino-3-cyanothiophene. In this route, the halogenation step requires careful selection of halogenating reagents and reaction conditions to ensure that halogen atoms are accurately introduced into the desired position without affecting the stability of the thiophene ring. During the cyanidation reaction, the activity of the cyanide reagent and the pH and temperature of the reaction system all have a significant impact on the yield and selectivity of the reaction. The amination reaction also needs to consider the type of amination reagent, reaction solvent and catalyst, etc., in order to achieve the desired result.
Second, the method of synthesizing by cyclization reaction using small molecules containing sulfur, nitrogen and carbon as raw materials. Small molecules with suitable functional groups, such as nucleophiles containing sulfur and electrophiles containing nitrogen and cyano, are selected in a suitable reaction medium under the action of catalysts to undergo cyclization. In this process, the atoms in the molecule are cleverly combined to build a thiophene ring, and at the same time, amino and cyano groups are formed at specific positions. The key to the cyclization reaction lies in the structural design of the reactants, so that each functional group can react in an orderly manner under the reaction conditions, and the choice of catalyst is crucial, which not only affects the reaction rate, but also affects the selectivity of cyclization, that is, to ensure the formation of the target product 2-amino-3-cyanothiophene, rather than other isomers.
Third, the coupling reaction of metal catalysis is the core method. Using the unique activity of metal catalysts, the compounds containing thiophene structure halide or other leaving groups can be coupled with reagents containing amino and cyanyl groups. Metal catalysts can activate reactant molecules and promote the formation of carbon-nitrogen and carbon-cyanide bonds. In such reactions, the type of metal catalysts and the structure of ligands have a significant impact on the activity and selectivity of the reaction. Reasonable selection of metal catalysts and ligands, control of reaction temperature, time and ratio of reactants, can effectively improve the synthesis efficiency and purity of 2-amino-3-cyanothiophene.

The price of 2-amino-3-cyanothiophene in the market is difficult to determine immediately. The price of this substance often varies due to many reasons, such as the trend of supply and demand, the method of preparation, the difference in quality, and even the fluctuation of market conditions and the change of seasons.
Looking at the market in the past, the price of this substance fluctuates quite a lot. If the supply exceeds the demand, the price may drop; and when the demand exceeds the supply, the price often rises. And the difficulty of the preparation process is also related to the cost, which in turn affects the price. The preparation method of fine research, the cost may be high, but the quality may be excellent, and the price may be high; the simple method, the cost may be low, and the price may be slightly lower.
In addition, the distinction between quality is also the key to pricing. Those with high purity are often required for specific applications, and the price must be high; while those with lower purity can be used for general purposes, the price may be relatively low.
The dynamics of the market also affect its price. Economic boom and bust, policy boom and bust, can change supply and demand, causing price fluctuations. As for the change of seasons, although not the main reason, but in some special times, or due to the convenience of raw material harvesting and transportation, the price is slightly different. < Br >
Therefore, in order to know the exact current price of 2-amino-3-cyanothiophene, it is necessary to carefully investigate the current market, consult various suppliers, and make comprehensive comparisons to obtain more accurate numbers. It is difficult to generalize based on the past alone.

2-Amino-3-cyanothiophene is an organic compound. Its storage conditions are crucial, related to the quality and stability of this compound.
When stored, the drying environment is the first. This compound is afraid of water, and in case of moisture, it is prone to reactions such as hydrolysis and deterioration. Therefore, when placed in a dry place, a desiccant can be prepared in the storage place to absorb water vapor and keep it dry.
Times and temperature. It should be stored in a cool place to avoid high temperature and hot topics. If the temperature is too high, it may cause changes in the internal structure of the compound, accelerating its decomposition or other adverse reactions. In general, a low temperature environment of 2-8 ° C is preferred. This temperature range can slow down its chemical reaction rate and prolong its storage time.
Furthermore, light must be protected. Light can also promote photochemical reactions, damaging its structure and properties. When stored in an opaque container, or placed in a dark place to block the intrusion of light.
Also, the storage place should be well ventilated. If the ventilation is not smooth, the volatile gas of the compound will gather in one place, which may increase the risk of explosion and poisoning. And good ventilation can keep the air in the environment fresh and reduce the influence of external factors on the compound.
In addition, this compound has certain toxicity and irritation, and safety procedures should be strictly followed when stored. The label is clear, its nature and harm are clearly explained, and it is stored in a place managed by a special person, and unrelated people are prohibited from approaching to prevent accidents.
In summary, the storage of 2-amino-3-cyanothiophene must be dry, cool, protected from light, ventilated, and follow safety regulations to ensure its quality for a long time for subsequent use.