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What are the main uses of 2-Amino-3- (2-chlorobenzoyl) -5-ethylthiophene?
2-Amino-3- (2-chlorobenzoyl) -5-ethylthiophene is used in various fields of medicine and chemical industry.
In the field of medicine, it is an important organic synthesis intermediate and plays a key role in the process of creating new drug molecules. Chemical modification and derivatization can be used to construct compounds with diverse structures, providing many possibilities for the development of new drugs for the treatment of diseases such as inflammation and tumors. Taking the development of cancer drugs as an example, researchers hope to use such intermediates to construct molecules with high selective inhibitory activity on tumor cells and reduce their damage to normal cells, which is of great significance for improving the therapeutic effect of tumors and the quality of life of patients.
In the field of chemical industry, it can also be used in materials science. It can be used to prepare functional materials with special properties, such as photoelectric materials. Because its molecular structure contains specific groups such as thiophene ring and benzoyl group, it endows the material with unique photoelectric properties, and can be applied to organic Light Emitting Diode (OLED), solar cells and other devices to help improve the performance and efficiency of such devices, and promote the evolution of chemical materials to high performance and multi-functionality.
Due to its structural characteristics and reactivity, this compound has shown broad application prospects in the fields of medicine and chemical industry, injecting new vitality and opportunities into the innovation and development of related fields.
What are the physical properties of 2-Amino-3- (2-chlorobenzoyl) -5-ethylthiophene?
2-Amino-3- (2-chlorobenzoyl) -5-ethylthiophene, this is an organic compound. Looking at its physical properties, at room temperature, or as a solid, the cover is relatively regular and solid due to its intermolecular force. Its melting point and boiling point are closely related to the molecular structure. The molecule contains rigid structures such as benzene ring and thiophene ring, and has polar groups, which enhances the intermolecular force, so the melting point, boiling point or higher.
In terms of solubility, because the molecule has both polar and non-polar parts, it may have certain solubility in organic solvents such as dichloromethane and chloroform. Because the non-polar part of these organic solvents can interact with the non-polar structures of the molecule such as benzene ring and thiophene ring, and the polar part can interact with the polar groups of the molecule such as amino group and carbonyl group. However, the solubility in water is not good, because the polarity of water molecules is strong, the interaction with the non-polar part of the compound molecule is weak, and it is difficult to overcome the intermolecular force to dissolve it.
Its density is also related to the molecular structure and relative molecular weight. The molecular structure is tight and the relative molecular weight is large, and the density is large.
Appearance may be white to light yellow powder, which is related to the absorption and reflection characteristics of the molecule to light. Its molecular structure causes the absorption and reflection of specific wavelengths of light, which in turn presents this color characteristic.
The physical properties of this compound are crucial in the fields of organic synthesis, drug development, etc., which help researchers to separate, purify, and determine reaction conditions according to their properties.
What are the chemical properties of 2-Amino-3- (2-chlorobenzoyl) -5-ethylthiophene?
2-Amino-3- (2-chlorobenzoyl) -5-ethylthiophene, this is an organic compound. Its chemical properties are quite complex and have multiple unique properties.
First of all, its physical properties, under room temperature, or as a solid, but the exact melting point, boiling point, etc., need to be accurately determined by experiments. Its appearance may be white to light yellow powder, due to differences in purity and crystal form, the appearance may change.
From the perspective of chemical activity, the amino group (-NH2O) in the molecule is alkaline and can react with acids to generate corresponding salts. This property is of great significance in organic synthesis, which can be used to separate and purify compounds by reacting with acids, or to form new chemical bonds.
Furthermore, the presence of 2-chlorobenzoyl moiety enhances the electrophilicity of molecules. The carbonyl group of benzoyl (C = O) can undergo many reactions, such as nucleophilic addition reactions. Because carbonyl carbons are partially positively charged, they are vulnerable to attack by nucleophilic reagents, such as alcohols and amine reagents, which can form esters, amides and other derivatives, which are important reaction check points in the design of organic synthesis routes.
In the 5-ethylthiophene part, the thiophene ring has aromatic properties, which makes its chemical properties relatively stable. However, the substituents on the thiophene ring will affect the electron cloud distribution of the thiophene ring, and the electron cloud density of the ethyl group may increase, thereby affecting the activity and selectivity of other reactions on the ring.
In addition, the solubility of the compound is also a key property. It may have a certain solubility in organic solvents such as dichloromethane, chloroform, and tetrahydrofuran. This property is convenient for its application in organic synthesis operations and reaction systems. It can be used as a reaction medium to promote the smooth progress of the reaction. < Br >
The chemical properties of this compound are rich and diverse, and it has potential application value in the field of organic synthesis, but the specific properties still need to be carefully explored and verified through experiments.
What is the synthesis method of 2-Amino-3- (2-chlorobenzoyl) -5-ethylthiophene?
To prepare 2-amino-3- (2-chlorobenzoyl) -5-ethylthiophene, the method of organic synthesis is often followed. First, thiophene derivatives are used as the starting material, which is the root material.
First, the thiophene derivative is reacted with an ethyl-containing reagent under specific conditions, and ethyl is introduced. In this step, a suitable reaction solvent, such as a non-protic organic solvent, is selected to facilitate the reaction, and at a moderate temperature, or heating or room temperature, depending on the activity of the reactants, the ethyl group is successfully connected to the specific position of the thiophene ring to obtain a thiophene intermediate containing ethyl. < Br >
Then, the intermediate meets the 2-chlorobenzoylation reagent. This reaction requires the assistance of appropriate catalysts, such as Lewis acid catalysts, to promote the acylation reaction. The pH, temperature and other conditions of the reaction system also need to be precisely controlled, so that the 2-chlorobenzoyl group is successfully connected to the corresponding check point of the thiophene ring to obtain another intermediate.
Finally, the amination operation of this intermediate is performed. Ammonia source reagents can be selected. In a suitable reaction environment, or under specific pressure and temperature, the amino group can be substituted for the corresponding position to obtain 2-amino-3- (2-chlorobenzoyl) -5-ethylthiophene. After each step of the reaction, it needs to be separated and purified, such as column chromatography, recrystallization, etc., to remove impurities, maintain the purity of the product, and make the synthesis process smooth and the product achieve the expected quality.
What is the price range of 2-Amino-3- (2-chlorobenzoyl) -5-ethylthiophene in the market?
I don't know what the price range of "2 - Amino - 3 - (2 - chlorobenzoyl) - 5 - ethylthiophene" is in the market. This is a fine chemical, and its price is determined by many factors.
First, purity is the key factor. If the purity is extremely high, it is almost used in high-end scientific research or specific high-demand industrial processes, and the price will be high; if the purity is slightly lower, it is suitable for general industrial processes, and the price may drop slightly.
Second, the market supply and demand have a great impact. If there is a strong demand for this product by many companies at a certain time and the supply is limited, the price will rise; conversely, if the supply exceeds the demand, the price will decline.
Third, the production process also plays a role. For a complex and high-cost process, the price of the product produced must not be low; if the process is simple and the cost is controllable, the price may be relatively close to the people.
Fourth, different merchants have different pricing strategies. Large and well-known enterprises may set prices higher than ordinary merchants due to factors such as brand and quality assurance.
However, I have checked all the books I know, but I have not been able to obtain the exact price range. For details, you can consult chemical product suppliers, relevant trade platforms, or communicate with the chemical industry to obtain a more accurate price range.