2 Acetyl 4 Bromothiophene
quinoline thiophene imidazole thiazole

2-Acetyl-4-bromothiophene

Taiy Chemical

    Specifications

    HS Code

    641976

    Chemical Formula C6H5BrOS
    Molecular Weight 191.07
    Appearance Solid (Typical description)
    Melting Point Data may vary depending on purity
    Boiling Point Data may vary depending on purity
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
    Density Data may vary depending on conditions
    Flash Point Data may vary depending on purity
    Odor Characteristic odor

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    General Information
    Where to Buy 2-Acetyl-4-bromothiophene in China?
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    Frequently Asked Questions

    As a leading 2-Acetyl-4-bromothiophene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2-Acetyl-4-bromothiophene?
    2-Acetyl-4-bromothiophene is an important compound in the field of organic chemistry. Its chemical properties are unique and it plays a key role in many chemical reactions and synthesis processes.
    First of all, in this compound, the bromine atom has high activity. Due to its electronegativity difference, the bromine atom is prone to nucleophilic substitution. When a suitable nucleophilic reagent is present, the bromine atom can be replaced by other groups. For example, if a hydroxyl nucleophilic reagent is introduced, the bromine atom can be replaced by a hydroxyl group through nucleophilic substitution to form a new compound containing hydroxyl groups. This process is very important in the construction of organic molecules with specific structures.
    Furthermore, the acetyl group also affects the properties of the compound. The carbonyl group of the acetyl group has a certain polarity and can participate in a variety of reactions. For example, under basic conditions, the carbonyl group can undergo nucleophilic addition reactions. Some reagents with active hydrogen, such as alcohols or amines, can be added to the carbonyl group, thereby changing the molecular structure and properties. Moreover, the presence of acetyl groups also affects the electron cloud distribution of the thiophene ring, resulting in changes in the reactivity of different positions on the thiophene ring.
    In addition, the thiophene ring of 2-acetyl-4-bromothiophene is itself aromatic. This allows it to undergo aromatic electrophilic substitution reactions like other aromatic compounds. Due to the localization effect of bromine atom and acetyl group, electrophilic reagents will selectively attack specific positions on thiophene rings, so as to achieve precise modification and construction of molecular structures, which is of great significance in organic synthesis chemistry.
    In short, 2-acetyl-4-bromothiophene contains bromine atoms, acetyl groups and thiophene rings, which have rich chemical properties and have broad application prospects in organic synthesis, pharmaceutical chemistry and other fields.
    What are the main uses of 2-Acetyl-4-bromothiophene?
    2-Acetyl-4-bromothiophene is one of the organic compounds. It has a wide range of uses and is often a key intermediate in the field of pharmaceutical synthesis. Due to its special chemical structure, it can construct complex molecular structures with biological activity through many chemical reactions, and then be used to create new drugs, such as antibacterial and anti-inflammatory drugs.
    In the field of materials science, it also has important uses. It can be introduced into the structure of polymer materials through specific chemical reactions to improve the properties of materials, such as improving the stability and conductivity of materials, and has many applications in organic optoelectronic materials. < Br >
    In the field of fine chemicals, this compound can be used to prepare special fragrances, dyes and other fine chemicals. Due to its unique structure, it endows the prepared products with unique characteristics and advantages, such as unique color and odor.
    In summary, 2-acetyl-4-bromothiophene plays an important role in many fields such as medicine, materials, and fine chemicals, and contributes greatly to the development of various fields.
    What are 2-Acetyl-4-bromothiophene synthesis methods?
    The synthesis method of 2-acetyl-4-bromothiophene has been explored by many parties throughout the ages. One of the methods can be initiated by thiophene. The thiophene is acetylated by the schilling, and the acetyl group is introduced. In this process, with an appropriate acylation reagent, such as acetyl chloride or acetic anhydride, under the action of a suitable catalyst, such as anhydrous aluminum trichloride, under a specific reaction environment, such as a suitable temperature and solvent, the specific position of the thiophene can be acetylated to obtain a thiophene derivative containing acetyl groups.
    Then, the derivative is brominated again. Select a suitable brominating reagent, such as liquid bromine or N-bromosuccinimide (NBS), under appropriate initiation conditions, such as light or the presence of a free radical initiator, the acetylated thiophene derivative is introduced into the bromine atom at a specific position. After subsequent separation and purification steps, 2-acetyl-4-bromothiophene is finally obtained.
    Another way is to brominate thiophene first to obtain bromothiophene. After that, the acetylation reaction is carried out, and the acetyl group is introduced into the appropriate position of bromothiophene through reasonable regulation of the reaction conditions. After multi-step operation, the purpose of synthesizing 2-acetyl-4-bromothiophene can also be achieved. All methods need to carefully control the reaction conditions, weigh the raw material cost, reaction yield and purity and many other factors to obtain the ideal synthesis effect.
    2-Acetyl-4-bromothiophene What are the precautions in storage and transportation?
    2-Acetyl-4-bromothiophene is an organic compound. During storage and transportation, the following things must be paid attention to:
    One is the storage environment. This compound should be stored in a cool, dry and well-ventilated place. Because it is more sensitive to heat, high temperature is easy to decompose or deteriorate, so the temperature should be controlled in an appropriate range, away from heat and fire sources. Humid environments may trigger reactions such as hydrolysis, so it is essential to keep it dry.
    The second is about packaging. It needs to be packed in a well-sealed package to prevent contact with air. Due to oxygen, moisture, etc. in the air or reaction with 2-acetyl-4-bromothiophene, its quality is affected. Packaging materials should also be carefully selected to ensure that no chemical interaction with compounds occurs.
    The third is transportation safety. Be sure to avoid violent vibrations and collisions during transportation to prevent package damage. If the package is broken and the compound leaks, it may not only cause loss, but also cause harm to the environment and personnel. At the same time, the means of transportation should also maintain suitable temperature and humidity conditions.
    Fourth, the label is clear. The name, nature, hazard warning and other information of the compound should be clearly marked on the storage container and transportation package. In this way, the staff can quickly understand its characteristics and take appropriate protection and response measures when handling.
    The fifth is to store in isolation. Do not mix or mix with oxidants, acids, bases and other substances, because of their active chemical properties, contact with these substances or cause severe chemical reactions, resulting in serious consequences such as fire and explosion.
    When storing and transporting 2-acetyl-4-bromothiophene, all of the above things need to be treated with caution and operated in strict accordance with regulations to ensure its quality and safety.
    What is the market price of 2-Acetyl-4-bromothiophene?
    The market price of 2-acetyl-4-bromothiophene is difficult to sum up. Its price often changes for various reasons.
    The first factor is the raw material. The price of the raw material is the main factor in the preparation of this compound. If the raw material used in the synthesis is difficult to find due to changes in weather, geographical conditions or supply and demand, the price of 2-acetyl-4-bromothiophene will also rise. If the supply of raw materials is sufficient and the price is stable, the cost is controllable, and the market price can be relatively stable.
    The second is the preparation process. Sophisticated and efficient technology can reduce production time and cost. If there are new technologies that can reduce steps, increase productivity, and reduce energy consumption, they will be able to reduce their production costs and win at a low price in the market. On the contrary, outdated and complicated processes are time-consuming, low yield, and high energy consumption, resulting in high costs and high prices.
    Furthermore, market supply and demand determine their prices. If at some point, many industries such as medicine and materials have a large increase in demand for 2-acetyl-4-bromothiophene, and the supply is insufficient, the price will soar. However, if the demand is weak and the supply is too large, the merchants will sell or reduce the price.
    In addition, the manufacturer's brand and product quality are also affected. Well-known large factories with strict quality control, high product purity and excellent quality. Although the price is high, there are many believers. Products from unknown small factories may be sold at low prices due to poor quality.
    International situation, policies and regulations also play a role. Trade barriers, tariff adjustments, or changes in the transportation costs of raw materials and products, affecting prices. As environmental protection policies become stricter, production requires increased environmental protection inputs, which also increases costs and moves prices.
    Therefore, in order to know the exact market price of 2-acetyl-4-bromothiophene, it is necessary to carefully observe various factors and track market dynamics in real time.