2 5 Dichlorothiophene 3 Carboxylic Acid
quinoline thiophene imidazole thiazole

2,5-Dichlorothiophene-3-carboxylic acid

Taiy Chemical

    Specifications

    HS Code

    612309

    Chemical Formula C5H3Cl2O2S
    Molar Mass 199.049 g/mol
    Appearance Solid (usually a powder or crystalline solid)
    Physical State At Room Temperature Solid
    Solubility In Water Poorly soluble in water
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
    Melting Point Typically in the range of 160 - 170 °C (approximate, can vary based on purity)
    Density No widely - reported standard density value, but density related to solid state packing
    Acidity Carboxylic acid group makes it acidic, pKa values around 3 - 4 (approximate)

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    General Information
    Where to Buy 2,5-Dichlorothiophene-3-carboxylic acid in China?
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    Frequently Asked Questions

    As a leading 2,5-Dichlorothiophene-3-carboxylic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,5-dichlorothiophene-3-carboxylic acid?
    2% 2C5-dihydroxybenzoic acid-3-methoxybenzoic acid, also known as vanillic acid, its main uses are as follows:
    Vanillic acid can be used as a synthetic raw material for a variety of drugs in the field of medicine. Because of its certain biological activity, it has a positive regulatory effect on human physiology. For example, in the preparation of some antibacterial drugs, vanillic acid can exert its antibacterial properties and help enhance the inhibition and killing effect of drugs on bacteria. At the same time, it also has potential effects in regulating human immunity. It will be taken into account in the development of some immunomodulatory drugs to help the body resist various diseases by regulating the immune system.
    In the food industry, vanillic acid can be used as a food additive. It has a unique flavor, which can add a different aroma and taste to the food, and improve the flavor quality of the food. In some baked goods, vanillic acid can give the product a more rich and unique fragrance, enhancing consumers' appetite. Moreover, it also has certain antiseptic properties, which can prolong the shelf life of food, reduce the risk of food deterioration, and ensure the quality and stability of food during the shelf life.
    In the field of cosmetics, vanillic acid is also quite popular. Due to its antioxidant properties, it can effectively remove free radicals in the skin and slow down oxidative damage to skin cells, thereby delaying skin aging. Adding it to skin care products can enhance the antioxidant effect of the product, prevent skin wrinkles, and keep the skin firm and elastic. At the same time, vanillic acid has a soothing effect on skin inflammation, can help relieve skin allergies and other uncomfortable symptoms, and is suitable for the development of cosmetics for people with sensitive skin.
    What are the physical properties of 2,5-dichlorothiophene-3-carboxylic acid?
    2% 2C5-difluorobenzoic acid-3-enoic acid is a kind of organic compound. Its physical properties are unique, which are related to the morphology, melting point, solubility and other characteristics of this substance.
    Looking at its morphology, under normal temperature and pressure, it is mostly white to light yellow crystalline powder. This morphology is easy to store and use, and the surface area of the powdered substance is large. In chemical reactions, it is easier to contact with other substances and promote the reaction.
    As for the melting point, it is about [X] ° C. The characteristics of the melting point can be used to identify the purity of the substance. If the purity is high, the melting point is relatively fixed and the deviation is small; conversely, if it contains impurities, the melting point may decrease and the melting range becomes wider. The boiling point is also an important physical property. However, due to the particularity of the structure of the substance, it is heated or easily decomposed. Therefore, the accurate determination of the boiling point requires specific experimental conditions and methods.
    In terms of solubility, this substance has a certain solubility in organic solvents, such as ethanol, ether, etc. In ethanol, it can dissolve a certain amount at a specific temperature. This property allows it to be evenly dispersed in the reaction system with the help of organic solvents such as ethanol in the organic synthesis reaction, which is conducive to the full occurrence of the reaction. In water, the solubility is relatively small. Due to its molecular structure, hydrophobic groups account for a large proportion, resulting in weak interaction with water molecules.
    In addition, the density of this substance is also one of its physical properties. Although the specific value will vary slightly due to the measurement conditions, it is roughly in the range of [X] g/³ cm. The density data is of important reference value in the measurement of materials in chemical production and the design of reaction vessels.
    The above physical properties are all key parameters in scientific research, chemical production and other fields, and play an indispensable role in the research and application of 2% 2C5-difluorobenzoic acid-3-enoic acid.
    What are the chemical synthesis methods of 2,5-dichlorothiophene-3-carboxylic acid?
    There are several common methods for the synthesis of 2% 2C5-difluorobenzoic acid-3-aldehyde:
    First, fluorobenzene derivatives are used as starting materials to construct aldehyde and carboxyl groups through multi-step reactions. Fluorobenzene can be halogenated at a specific location first, and then the aldehyde group can be introduced through the reaction of metal reagents, such as Grignard reagent or lithium reagent, with the corresponding carbonyl compound, and then the carboxyl group can be obtained by oxidation. This process requires precise control of the reaction conditions. The reaction conditions at each step are quite critical, such as the temperature of the halogenation reaction, the proportion of reagents, and the anhydrous and anaerobic environment during the reaction of metal reagents. A slight difference will affect the yield and purity. < Br >
    Second, the electrophilic substitution reaction strategy of aromatic compounds is adopted. Taking advantage of the electron cloud characteristics of fluorobenzene rings, a suitable electrophilic reagent is selected, and the aldehyde group precursor is first introduced, and then the carboxyl group is converted through the functional group. For example, the Fu-gram acylation reaction is carried out with a suitable acylating reagent, and then the obtained product is oxidized and hydrolyzed. However, the selectivity of the electrophilic substitution reaction region is high, and it is necessary to select the appropriate reaction conditions and reagents according to the existing substituent localization effect on the benzene ring to ensure that the aldehyde group and the carboxyl group are formed at the target position.
    Third, the coupling reaction catalyzed by transition metals. Such as palladium-catalyzed coupling reaction, fluorinated halogenated aromatics are coupled with organometallic reagents or nucleophiles containing aldehyde and carboxyl groups. This method is efficient and selective, but the cost of transition metal catalysts is high. Factors such as catalyst dosage, ligand selection and reaction solvent in the reaction have a significant impact on the reaction process and results, and need to be carefully regulated.
    What is the price range of 2,5-dichlorothiophene-3-carboxylic acid in the market?
    The price of 2% 2C5-dihydroxybenzoic acid-3-methoxybenzoic acid in the market is difficult to say for sure. Its wide price depends on various reasons.
    First, whether the quality is pure or not is a big obstacle. If its quality is pure and high, and there are few impurities, the price will be very high; if the quality is not high, it contains more impurities, and the price may drop slightly. Second, the trend of supply and demand is also the key. If the market is prosperous and the supply is small, the price will rise; if the supply exceeds the demand, the price will fall. Furthermore, the method of production and the cost of the original also affect the price. If the preparation method is simple and the cost is low, the price may decrease; if the preparation is difficult and the cost is high, the price will increase.
    Under normal circumstances, if the quality of this product is still good, in the chemical raw material market, the price per kilogram may be in the hundreds of yuan spectrum. However, for fine chemicals, the quality is high, and the price may be as high as several thousand yuan per kilogram. In pharmaceutical research and development, because of its small dosage, the quality is demanding, and the price is even higher, or more than 10,000 yuan per kilogram.
    But the market conditions are fickle, and the price often varies according to time, place and situation. To know the exact price, you must visit the chemical raw material supplier, trader, or observe the real-time quotation of the market before you can get it.
    What are the manufacturers of 2,5-dichlorothiophene-3-carboxylic acid?
    There are many manufacturers of 2% 2C5-dihydroxybenzoic acid-3-methoxy in the world of creation. However, there are only a few who can be called good.
    There is a factory in Jiangnan called Ruihua. The craftsmen in the factory all have unique skills and have been studying the way of chemical industry for many years. The 2% 2C5-dihydroxybenzoic acid-3-methoxy produced is of high quality and stable quantity. The raw materials are selected, the process is rigorous, and every step follows the ancient method and integrates new technologies. From the raw materials entering the factory to the finished product coming out, there are special personnel to monitor, and there should be no mistakes. Therefore, its products are quite praised in the market, and many merchants are fortunate to have Ruihua's products.
    There is also a factory in Saibei, named Hongtai. This factory is located in a vast land and has abundant resources. It has taken a different approach in the production of 2% 2C5-dihydroxybenzoic acid-3-methoxy. Using a unique process, the products made have distinct characteristics. Although it is located in a remote area, its reputation is far-reaching, all because of its uniqueness and can meet the diverse needs of the market.
    There is another Fengyuan factory in Lingnan, which takes innovation as the key. There are many talents in the factory, and new techniques are often developed. Its method of producing 2% 2C5-dihydroxybenzoic acid-3-methoxy keeps pace with the times. The finished products are not only of high quality, but also can conform to the market trend. In terms of packaging and purity, they are all novel, attracting customers from all over the world to compete for them.
    These manufacturers, either by virtue of their exquisite skills, or by their unique craftsmanship, or by their innovative ability, lead the way in the production of 2% 2C5-dihydroxybenzoic acid-3-methoxy, and are leaders in the industry.