2 5 Dichloro 3 Thiopheneformic Acid
quinoline thiophene imidazole thiazole

2,5-Dichloro-3-Thiopheneformic Acid

Taiy Chemical

    Specifications

    HS Code

    496237

    Chemical Formula C5H2Cl2O2S
    Molar Mass 197.04 g/mol
    Appearance Solid
    Color White to off - white
    Melting Point 163 - 167 °C
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO, DMF
    Pka Typical for carboxylic acids, around 3 - 5
    Stability Stable under normal conditions, but may react with strong bases and oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2,5-Dichloro-3-Thiopheneformic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2,5-dichloro-3-thiophenecarboxylic acid?
    The chemical properties of 2% 2C5-difluoro-3-methoxybenzoic acid are quite specific. This compound is acidic, because it contains a carboxyl group (-COOH). This carboxyl group can release protons under suitable conditions, showing the property of acid. It can neutralize and react with bases to generate corresponding salts and water.
    And the fluorine atom and methoxy group in the molecule also give unique properties. The electronegativity of fluorine atoms is very strong, which can affect the electron cloud distribution of molecules, so that the compound has high stability and special physical and chemical properties. Methoxy (-OCH) is the power supply group, which can affect the electron cloud density of the benzene ring and change the reactivity of the compound to a certain extent. < Br >
    In chemical reactions, because of its carboxyl group, it can participate in the esterification reaction and form ester compounds with alcohols catalyzed by acids. And because of the structure of the benzene ring, electrophilic substitution reactions can be carried out, and the positioning effect of fluorine atoms and methoxy groups will affect the position of the substituents entering the benzene ring. The presence of fluorine atoms may cause the compound to exhibit different reaction rates and selectivity from fluorine-free analogs in some reactions. In terms of physical properties, due to the characteristics of the molecular structure, it may have a certain solubility in organic solvents, and the melting boiling point is also determined by the intermolecular force, which is affected by the fluorine atom and methoxy group.
    What are the main uses of 2,5-dichloro-3-thiophenecarboxylic acid?
    2% 2C5-difluoro-3-methoxybenzoic acid, which was not available in the era of Tiangong Kaiwu. However, from today's perspective, its main uses are as follows:
    First, in the field of medical chemistry, it is an important organic synthesis intermediate. Today's pharmaceutical research and development often requires the construction of specific molecular structures to achieve therapeutic effects. The fluorine atoms and methoxy groups of this compound can significantly change the physical, chemical and biological activities of the compound. Through chemical reactions, specific functional groups are connected to synthesize drug molecules with unique pharmacological activities, or can be used for the creation of antibacterial, anti-inflammatory, anti-tumor and other drugs.
    Second, it also has important applications in the field of materials science. Due to the characteristics of fluorine atoms, the weathering resistance, chemical stability and low surface energy of materials can be improved. The structure containing this compound can be introduced into polymer materials to prepare coatings and plastics with special properties. If the prepared coating has better anti-fouling and corrosion resistance, it can be applied to surfaces such as buildings and automobiles to prolong its service life.
    Third, it also plays a key role in the field of pesticide chemistry. Using it as a raw material, chemically modified and synthesized, high-efficiency, low-toxicity and environmentally friendly pesticides can be created. Its special structure can enhance its biological activity against specific pests or weeds, accurately attack target organisms, and have little impact on non-target organisms, which is in line with the development direction of green pesticides today.
    Although this product is not included in "Tiangong Kaiwu", today, it has indispensable and important uses in many fields such as medicine, materials, pesticides, etc., promoting technological progress and development in various fields.
    What are the synthesis methods of 2,5-dichloro-3-thiophenecarboxylic acid?
    The synthesis of 2% 2C5-difluoro-3-methoxybenzoic acid is an important topic in organic chemistry. There are many methods, and the following are described in detail by Jun.
    One is a method using benzoic acid as the starting material. Benzoic acid can be halogenated to introduce fluorine atoms. When halogenating, it is crucial to choose the appropriate halogenating reagent and reaction conditions. Commonly used halogenating reagents, such as fluorohalogenating agents, can halogenate the benzene ring of benzoic acid at a specific position at a specific temperature and in the presence of a catalyst, introducing fluorine atoms to form fluorobenzoic acid intermediates. Then, this intermediate can be methoxylated to introduce methoxy groups. The methoxylation reaction usually requires a base and a suitable methoxylation reagent, such as dimethyl sulfate. Under appropriate reaction conditions, the target product 2% 2C5-difluoro-3-methoxybenzoic acid can be obtained.
    The second method is to use other aromatic compounds as starting materials. For example, an aromatic compound with suitable substituents is selected and converted into the target product through a multi-step reaction. A fluorine atom can be introduced into the aromatic ring through a substitution reaction, and then other functional group conversion reactions, such as oxidation and esterification, can adjust the molecular structure. Finally, 2% 2C5-difluoro-3-methoxybenzoic acid is successfully synthesized through a methoxylation step. This approach requires fine planning of reaction steps and conditions to ensure the smooth progress of each step of the reaction and the purity of the product.
    Third, there is also a synthesis strategy catalyzed by transition metals. Transition metal catalysts can efficiently promote various reactions, such as the formation of carbon-fluorine bonds and carbon-oxygen bonds. In the presence of suitable transition metal catalysts, such as palladium, copper and other catalysts, with corresponding ligands, the reaction can be selectively carried out, so as to achieve the synthesis of 2% 2C5-difluoro-3-methoxybenzoic acid. This method often has the advantages of mild reaction conditions and high selectivity, but the choice and cost of catalysts need to be carefully considered.
    All synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively weigh factors such as raw material availability, cost, reaction conditions and product purity requirements to choose the optimal synthesis path to achieve the purpose of efficient and economical synthesis of 2% 2C5-difluoro-3-methoxybenzoic acid.
    What is the market price of 2,5-dichloro-3-thiophenecarboxylic acid?
    I haven't heard of the market price of 2,5-difluoro-3-methoxybenzoic acid. However, if you want to know the price of this product, you can check it in detail in the market. In today's world, commerce is prosperous, and all kinds of goods are priced.
    Or you can visit various pharmaceutical shops and chemical material stores, and ask his shopkeeper and buddies, they are often involved in the sale of this product, and they should know its price. Or you can search for this product on the online platform of the market. There are many merchants on it, and the quotations are different, which can be compared to get a good price.
    The price of chemical raw materials often changes with time. The output of the place of origin, the situation of supply and demand, and the level of labor costs can all make it rise and fall. If there is a disaster at the place of origin, the output will drop sharply, and the price may rise; if the demand is sluggish and the supply exceeds the demand, the price may fall.
    To know the current market price of 2,5-difluoro-3-methoxybenzoic acid, you need to go to the city in person or inquire in detail on the online platform to get the exact number.
    What are the precautions for 2,5-dichloro-3-thiophenecarboxylic acid in storage and transportation?
    2% 2C5-difluoro-3-methoxybenzoic acid is an important raw material in organic synthesis. During storage and transportation, pay attention to the following matters:
    First, when storing, it should be placed in a cool and dry place. This compound is quite sensitive to humidity, and humid environments can easily cause reactions such as hydrolysis, which can destroy its chemical structure and reduce or even lose its original chemical activity. Therefore, a dry and well-ventilated warehouse should be selected, and the warehouse temperature should be maintained at a relatively low level to prevent the decomposition of compounds or other adverse reactions caused by excessive temperature.
    Second, because it has a certain chemical activity, it needs to be kept away from fire sources and oxidants. When 2% 2C5-difluoro-3-methoxybenzoic acid encounters an open flame or a strong oxidant, it is very likely to cause violent combustion or even explosion and other dangerous conditions. In the vicinity of the storage site, open flames are strictly prohibited, and they should be stored separately from dangerous chemicals such as oxidants, with clear isolation labels, and complete fire protection facilities and fire extinguishing equipment.
    Third, the packaging must be tight. This compound should be packaged with good sealing properties, such as glass bottles, plastic drums, etc., to ensure that the packaging is free of leakage. The packaging material should be able to withstand the chemical properties of the compound and will not react with it, thus ensuring the stable quality of the compound. On the outside of the package, the name, specifications, hazardous characteristics and other relevant information of the compound should be clearly marked to facilitate identification and management.
    Fourth, during transportation, the relevant transportation regulations should be strictly adhered to. Use transportation enterprises and transportation vehicles with corresponding qualifications, and transportation personnel should be familiar with the dangerous characteristics and emergency treatment methods of the compound. Transportation vehicles should be equipped with necessary emergency equipment and protective equipment, such as fire extinguishers, leakage emergency treatment tools, etc. During transportation, it is necessary to prevent vehicle bumps and collisions, and avoid compound leakage due to packaging damage.
    In summary, proper storage and transportation methods are essential to ensure the quality and safety of 2% 2C5-difluoro-3-methoxybenzoic acid.