2 5 Dibromo 3 Methylthiophene
quinoline thiophene imidazole thiazole

2,5-Dibromo-3-methylthiophene

Taiy Chemical

    Specifications

    HS Code

    502971

    Chemical Formula C5H4Br2S
    Molecular Weight 257.96
    Appearance Solid (usually a white to off - white powder)
    Boiling Point Around 230 - 240 °C (estimated, as it may decompose)
    Melting Point 48 - 52 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, etc.
    Density Approx. 2.08 g/cm³ (estimated)
    Odor Typical of organosulfur - containing compounds, may have a pungent sulfur - like odor
    Stability Stable under normal conditions but may react with strong oxidizing agents

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    Frequently Asked Questions

    As a leading 2,5-Dibromo-3-methylthiophene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2,5-dibromo-3-methylthiophene?
    2% 2C5-dibromo-3-methylpentane is also a monohalogenated hydrocarbon in organic chemistry. Its main use is quite extensive, and it plays a crucial role in the field of organic synthesis.
    One of them can be used as an intermediate in organic synthesis. The presence of bromine atoms and methyl groups in its molecular structure gives it unique reactivity. Through various chemical reactions, such as nucleophilic substitution reactions, bromine atoms can be replaced by other functional groups to build more complex organic compounds. For example, when reacted with sodium alcohol, corresponding ether compounds can be formed; when reacted with sodium cyanide, cyanyl groups can be introduced and further hydrolyzed to obtain carboxylic acids, which is of great significance in the design and development of organic synthesis routes.
    Second, it also has important applications in the field of medicinal chemistry. The synthesis of many drugs often uses 2% 2C5-dibromo-3-methylpentane as one of the starting materials. Its unique carbon chain structure and functional groups can be used as the basis for building the skeleton of drug-active molecules. Through subsequent chemical modifications and reactions, biologically active groups can be introduced to develop new drugs and help the development of medicine.
    Third, it can also play a role in materials science. It can participate in the synthesis of some special polymer materials. Through a specific polymerization reaction, its structural units are introduced into the polymer chain to change the properties of the material, such as improving the solubility, thermal stability, mechanical properties, etc., providing the possibility for the creation of new materials.
    2% 2C5-dibromo-3-methylpentane With its special structure and reactivity, it has shown non-negligible uses in many fields such as organic synthesis, pharmaceutical chemistry and materials science, promoting the progress and development of related science and technology.
    What are the physical properties of 2,5-dibromo-3-methylthiophene?
    2% 2C5-dibromo-3-methylfuran, this is an organic compound. Its physical properties are as follows:
    Looking at its properties, at room temperature, it is mostly colorless to light yellow liquid with clear texture. Smell it, or have a special smell, but this smell is not fragrant and pleasant, but has a certain irritation, smelling it for too long, or causing discomfort to the human body.
    In terms of its melting point, the melting point is low, and it is difficult to solidify at conventional ambient temperatures, always maintaining a liquid state; the boiling point is in a specific range due to intermolecular forces, and it usually needs to be heated to a certain temperature before it can boil and vaporize.
    Its solubility is also an important property. In organic solvents, such as common ethanol, ether, etc., it has good solubility and can be miscible with it to form a uniform solution; however, in water, the solubility is poor. Because of its molecular structure, hydrophobic groups account for a large proportion, making it difficult to dissolve in water, mixed with water, and easy to delaminate.
    In terms of density, it is larger than water. If it is placed in the same container as water, it can be seen that it sinks to the bottom of the water.
    The physical properties of this compound are of great significance in the fields of organic synthesis, chemical production, etc. Due to its solubility and density, it provides a key basis for chemical practitioners in the operation of separation, purification and reaction processes, helping them to rationally design the process flow and achieve the purpose of efficient production.
    What are the chemical properties of 2,5-dibromo-3-methylthiophene?
    2% 2C5-dibromo-3-methylfuran, this is an organic compound. Its chemical properties are unique, containing bromine atoms and methyl groups, which have a great impact on its properties.
    Let's talk about bromine atoms first, which have strong electronegativity, which enhances the polarity of molecules, making 2% 2C5-dibromo-3-methylfuran more likely to participate in polar reactions. For example, nucleophilic substitution reactions, bromine atoms are easily attacked by nucleophiles and leave to form new organic compounds. This is a common strategy for building carbon-heteroatom bonds in organic synthesis, which can produce a variety of compounds containing different functional groups and expand their applications in the field of organic synthesis.
    Furthermore, methyl groups, as power supply groups, can change the electron cloud density of the furan ring. Methyl groups give electrons, which increases the electron cloud density on the furan ring, especially the ortho and para-positions. This enhances the electrophilic activity of the furan ring, and electrophilic reagents are more likely to attack these positions. For example, when electrophilic substitution occurs, the substituents tend to enter the ortho and para-positions of the methyl group, providing direction for the synthesis of organic compounds with specific structures.
    2% 2C5-dibromo-3-methylfuran is active in the field of organic synthesis due to the presence of bromine atoms and methyl groups. It provides key intermediates for the preparation of various organic compounds and can construct complex and functional organic molecular structures through ingenious design of reaction routes.
    What are the synthesis methods of 2,5-dibromo-3-methylthiophene?
    To prepare 2,5-dibromo-3-methylfuran, the methods are as follows:
    First, start with furan, and first react with methylating reagents such as iodomethane and alkali under appropriate conditions to obtain 3-methylfuran. Then add 3-methylfuran and bromine in a suitable solvent such as dichloromethane at a low temperature such as about 0 ° C, slowly drop bromine and stir to obtain 2,5-dibromo-3-methylfuran. This process needs to pay attention to the strong oxidation and corrosiveness of bromine. It should be operated in a fume hood and the reaction temperature should be controlled to prevent side reactions such as excessive bromide.
    Second, a suitable furan derivative can be found, which has a methyl substituent in its structure and a suitable substitution position. Through a specific halogenation reaction, such as the use of N-bromosuccinimide (NBS) as a bromination reagent, in the presence of an initiator such as benzoyl peroxide, heated and refluxed in a suitable solvent such as carbon tetrachloride, the bromine atom is selectively substituted at the 2,5 position to obtain 2,5-dibromo-3-methylfuran. This method is milder and has relatively few side reactions, but attention should be paid to the control of the amount of NBS and the reaction conditions to achieve the best yield.
    Third, an organic synthesis route can also be considered to construct a furan ring from a simple raw material through a multi-step reaction and introduce methyl and bromine atoms. For example, a compound containing carbonyl and alkynyl groups is used as a starting material, and a furan ring is formed by cyclization, and then the target product is gradually prepared by methylation, bromination and other steps. Although this path has many steps, it can be optimized according to the availability of raw materials and the selectivity of the reaction to achieve efficient synthesis. However, the synthesis route is complex, and the reaction conditions of each step need to be carefully controlled to ensure the smooth progress of the reaction.
    What are the precautions for storing and transporting 2,5-dibromo-3-methylthiophene?
    2% 2C5-dibromo-3-methylfuran requires attention to many key matters during storage and transportation.
    For storage, first, a cool, dry and well-ventilated place should be selected. This is due to its nature or affected by temperature, humidity and air. If stored in a high temperature and humid place, it may decompose and deteriorate. Second, keep away from fire and heat sources. The substance has certain chemical activity and is at risk of burning or even exploding in case of open flame, hot topic or. Third, it should be stored separately from oxidants, acids, alkalis, etc., because it may react violently with these substances and cause danger. Fourth, the storage container must be sealed. If the sealing is not good, it is easy to evaporate and dissipate, and may also react with air components, and volatile gases or cause air pollution.
    When transporting, first of all, the transportation vehicle must have corresponding qualifications and protective facilities. For example, equipped with fire extinguisher materials to prevent fire, there are leakage emergency treatment equipment, and in case of leakage, it can be dealt with in time. Secondly, during transportation, ensure that the container does not leak, collapse, fall, or damage. Due to bumps and collisions or rupture of the container, the material leaks, endangering the safety of transporters and the environment. Furthermore, it is necessary to strictly follow the prescribed route to avoid sensitive areas such as densely populated areas and water sources. If a leak occurs on the way, more people are easily endangered in densely populated areas, and the water body will be polluted if it is close to the water source. In addition, transportation personnel need to undergo professional training, be familiar with the characteristics of the substance and emergency treatment methods, and be able to handle emergencies calmly and properly to reduce hazards.