2,5-Dibromo-3-butylthiophene

2% 2C5-dibromo-3-methylpyridine is a key intermediate in organic synthesis. In the field of organic synthesis, its uses are quite extensive.
One of them can be used as an arylation reagent. In many arylation reactions, with its specific structure, it can react with many nucleophiles to form carbon-carbon bonds, carbon-heteroatomic bonds, etc., which is of great significance for the synthesis of complex organic molecular structures. For example, in the palladium-catalyzed aromatization reaction, 2% 2C5-dibromo-3-methylpyridine can be combined with aromatic derivatives containing active hydrogen to form biaryl compounds with special structures, which have important applications in pharmaceutical chemistry, materials science and other fields.
Second, in the field of drug development, it is a key synthetic building block. The synthesis process of many biologically active drug molecules involves the introduction of other functional groups through multi-step reactions with 2% 2C5-dibromo-3-methylpyridine as the starting material, and finally the molecular structure with specific pharmacological activities is constructed. Like some inhibitors targeting specific disease targets, in its synthesis route, 2% 2C5-dibromo-3-methylpyridine can be used as a starting skeleton to obtain active molecules that meet the requirements after modification.
Third, in terms of materials science, it can be used to prepare functional organic materials. Polymer materials with specific optical and electrical properties can be synthesized by polymerization with other organic monomers. For example, after polymerization with conjugated monomers, polymers with fluorescent properties can be obtained, which have potential application value in organic Light Emitting Diode (OLED), fluorescent sensors and other fields.

2% 2C5-dibromo-3-methylpyridine, which is an organic compound. Its physical properties are as follows:
Under normal temperature, it is mostly colorless to light yellow liquid, or crystalline solid, depending on the specific purity and environmental conditions.
When it comes to melting point, according to relevant books, it is about [X] ° C, but this value will also fluctuate due to impurities and other factors. The determination of melting point is related to the purity identification of substances, and is crucial in many fields such as pharmaceutical and material preparation. < Br >
In terms of boiling point, it is roughly at [X] ° C. Its boiling point characteristics are a key consideration in chemical operations such as distillation and separation, so as to achieve effective separation of the compound from other substances.
As for solubility, this compound has certain solubility in common organic solvents, such as ethanol, ether, dichloromethane, etc. Its solubility in organic solvents provides a basis for the choice of reaction medium in organic synthesis; while in water, its solubility is relatively limited, which is of great application value in the extraction and separation process of substances.
In addition, the density of this compound is about [X] g/cm ³, and the determination of density is helpful for accurate measurement and control of the amount of reactant in chemical production. Its physical constants such as vapor pressure and refractive index are also of great significance for its identification and application. However, due to differences in ancient records and experimental conditions, some data may be slightly different. In practical applications, it needs to be carefully measured and verified according to specific circumstances.

2% 2C5-dibromo-3-methylpyridine, the chemical properties of this substance are relatively stable. In its structure, the pyridine ring has certain aromatic properties, giving the substance relatively stable characteristics. The introduction of dibromo substituents and methyl groups alters the electron cloud distribution, but the conjugated system of the pyridine ring remains stable.
Under normal circumstances, such compounds are not prone to spontaneous decomposition or significant chemical changes under normal conditions. However, its stability is not absolute. When encountering strong oxidizing agents, it may be oxidized due to the change of electron cloud density on the pyridine ring; under specific conditions of high temperature, high pressure and suitable catalysts, it will also participate in chemical reactions, such as substitution reactions with nucleophiles. This is because the bromine atom has a certain activity and can be attacked and replaced by nucleophiles under suitable conditions.
However, in the conventional environment and mild experimental conditions, 2% 2C5-dibromo-3-methyl pyridine can maintain a relatively stable state, providing a stable material basis for related chemical research and applications.

The synthesis of 2% 2C5-dibromo-3-pentanone is an important matter in organic synthesis. There are many methods, and the common ones are described here.
One can be started from ethyl acetoacetate. First, ethyl acetoacetate is treated with sodium alcohol to form an enolate anion, which has strong nucleophilicity. Then, it is reacted with 1,3-dibromopropane. Because the enolate anion is nucleophilic, it can attack the halogenated carbon of 1,3-dibromopropane, and it is replaced by a nucleophilic to form a carbon-carbon bond, resulting in an intermediate product. The intermediate product is then treated with dilute acid. After hydrolysis and decarboxylation, 2,5-dibromo-3-pentanone can be obtained. The reaction mechanism is clear and the steps are orderly. However, the operation needs to be controlled by conditions. The temperature and acidity of hydrolysis and decarboxylation have an impact on the yield.
Second, 3-pentanone is used as the starting material. First, bromine is reacted in an appropriate solvent in the presence of light or initiator. The α-hydrogen of 3-pentanone has a certain activity. Under the action of light or initiator, bromine can capture α-hydrogen and generate α-bromo-3-pentanone. The α-position of this product is enhanced by the electron-absorbing effect of bromine atom, and the α-hydrogen acidity is more likely to be replaced by bromine. Continue to react with bromine to obtain 2,5-dibromo-3-pentanone. The raw material of this route is easy to obtain, but the selectivity of bromination reaction needs to be carefully studied to avoid excessive by-products of polybromination, which affects the purity and yield of the product.
Third, diethyl malonate is used as the raw material. First, diethyl malonate is treated with sodium alcohol to form carbon negative ions, and reacts with 1,3-dibromopropane to construct a carbon chain. Then hydrolysis and decarboxylation are used to obtain glutaric acid. Glutaric acid can also be prepared by reduction, bromination and other steps. This route is a little complicated, but the reaction conditions of each step are relatively mild. If fine operation can be done, 2,5-dibromo-3-pentanone with higher yield and purity can also be obtained.
Synthesis of 2,5-dibromo-3-pentanone has advantages and disadvantages. In practical application, it is necessary to weigh the selection according to factors such as raw material availability, cost, reaction conditions and product requirements, and operate cautiously to effectively synthesize the target compound.

Today there is 2,5-dibromo-3-methylpentane, what is the price of it in the market? This is an organic compound, and the preparation method is quite complicated, requiring exquisite skills and specific raw materials. It is useful in chemical, pharmaceutical and other fields, but its market price often varies due to factors such as quality, supply and demand, and preparation cost.
If its quality is high, and the preparation cost is high, and when the market demand is strong, its price may be quite high; on the contrary, if the quality is ordinary, the preparation is easy to obtain, and the market is oversupplied, the price may be lower.
The current market situation has no exact value to explain. To know the details, you need to consult a merchant specializing in organic compounds, or visit a platform for chemical product trading, in order to obtain the current exact price.