2,5-bis-(benzoxazol-2-)thiophene

2%2C5-bis-%28benzoxazol-2-+%29thiophene is an organic compound. Its main application field is quite wide.
In the field of materials science, it is often used as a luminescent material. Because of its unique molecular structure, it can emit light of a specific wavelength under specific conditions, so it is often used in the preparation of organic Light Emitting Diodes (OLEDs). OLED displays are now widely used in mobile phones, TVs and many other display devices, 2%2C5-bis-%28benzoxazol-2-+%29thiophene can provide them with efficient luminous properties, making the display screen clearer and more colorful.
also has important applications in fluorescent probes. Because of its sensitivity to certain specific substances or environmental factors, it can interact specifically with the target, resulting in changes in fluorescence properties. With this property, scientists can use it to accurately detect specific molecules in organisms, such as in medical diagnosis, it can be used to detect disease markers and help early detection and diagnosis of diseases.
In the field of optoelectronic devices, it can be used as an active layer material. In optoelectronic devices such as solar cells, it helps to improve the absorption and conversion efficiency of the device to light, which is of great significance to the development of optoelectronic devices.
In addition, in the field of chemical sensors, 2%2C5-bis-%28benzoxazol-2-+%29thiophene can sensitively detect the presence and concentration changes of various chemical substances in the environment by virtue of its response characteristics to specific chemical substances, and plays a key role in environmental monitoring.
To sum up, 2%2C5-bis-%28benzoxazol-2-+%29thiophene has shown important application value in many fields such as materials, medicine, optoelectronic devices and environmental monitoring, and has a non-negligible role in promoting the progress of many scientific and technological fields.

To prepare 2,5-bis (benzoxazole-2-yl) thiophene, the method is as follows:
First take an appropriate amount of 2,5-thiophene dicarboxylic acid, place it in a clean reactor, and dissolve it with a specific organic solvent. This solvent needs to have good solubility and stable properties of the reactants. After dissolving, slowly add an appropriate amount of o-aminophenol. The molar ratio of the two should be precisely prepared according to the reaction requirements, generally between 1:2 and 1:2.5.
Then, add an appropriate amount of catalyst, such as concentrated sulfuric acid or a specific Lewis acid catalyst, and the amount is about 3% - 5% of the total mass of the reactants. Under stirring, gradually heat up to 150-180 ° C. This process requires strict control of the heating rate, preferably 2-3 ° C per minute, so that the reaction system can be heated evenly.
Keep this temperature for 6-8 hours. During this period, the reaction process can be closely observed. The consumption of reactants and the generation of products can be monitored by thin layer chromatography (TLC) or high performance liquid chromatography (HPLC). When the reaction is asymptotically complete, that is, the peak area of the reactants is greatly reduced and the peak area of the products is stable, the heating is stopped.
The reaction solution is cooled to room temperature, and solid matter can be seen at this time. The obtained solid is washed several times with a suitable organic solvent, such as ethanol or acetone. After each wash, the solid-liquid is separated by a suction filtration device until the filtrate is clear and colorless. The obtained solid is the crude product.
Then the crude product is purified by recrystallization method, and a suitable mixed solvent is selected, such as ethanol-water system, with a ratio of about 3:1 to 4:1. The crude product is completely dissolved by heating, and then slowly cooled. After the crystals are fully analyzed, the crystals are filtered again, and the crystals are collected. They are dried in a vacuum oven at 50-60 ° C for 3-4 hours to obtain a pure 2,5-bis (benzoxazole-2-yl) thiophene product.

2% 2C5 - bis - (benzoxazol - 2 -) thiophene, that is, 2,5 - bis (benzoxazol - 2 - yl) thiophene, this substance has many unique physical and chemical properties.
Its appearance is often crystalline, with high stability. It is difficult to react with other substances in conventional environments and can be stored for a long time. This is due to the conjugate system formed by benzoxazole and thiophene in the molecular structure, which gives it special stability.
From the perspective of optical properties, this substance has significant fluorescence properties. Excited by a specific wavelength of light, the electron transitions, and then emits fluorescence. This fluorescent emission efficiency is high and the fluorescent color can be fine-tuned due to the environment, which is of great significance in the field of fluorescent materials. For example, in the production of fluorescent probes, with their sensitivity to specific environmental changes, accurate detection of specific substances or physical and chemical parameters in living organisms can be achieved.
Thermal stability is also an important characteristic. It can withstand higher temperatures without decomposition or significant changes in properties, and the melting point is usually in the relatively high temperature range. This characteristic makes it excellent in high temperature application scenarios, such as electronic devices or material processing in high temperature environments, to maintain stable structure and performance.
In terms of solubility, it has certain solubility in common organic solvents such as chloroform and dichloromethane, but its solubility in water is extremely low. This property is extremely critical in the preparation and processing of materials, and suitable solvents can be selected to dissolve it to achieve film formation, solution processing, etc., to meet different application needs.
Its chemical properties are relatively active, and other functional groups can be introduced into specific positions on benzoxazole and thiophene rings through chemical reactions to achieve functionalization. By changing the molecular structure, its physical and chemical properties can be regulated to meet different applications, such as improving material conductivity and improving compatibility with other materials.

The exact price of 2,5-bis- (benzoxazole-2 -) thiophene is a rare chemical in the market, and its price often varies depending on quality, purity, purchase quantity, and supply.
If it is a high-purity scientific research grade, it is used by specialized chemical reagents. Due to the need for research and development, it is difficult to prepare, and the price may be high. If purchased in small quantities, it can reach hundreds or even thousands of yuan per gram.
If it is for industrial use, the purity is slightly lower, and the price may decrease according to the scale of production and market supply and demand. It is also possible to buy in batches for thousands of yuan per kilogram.
However, if you want to know the exact price, you can consult chemical reagent suppliers, chemical product trading platforms, or discuss with experts in industry forums to obtain a near-real price.

2%2C5-bis-%28benzoxazol-2-+%29thiophene, that is, 2,5-bis (benzoxazole-2-yl) thiophene, the stability of this substance is related to multiple ends, just like the ancient trade-off, when viewed from multiple aspects.
On chemical stability, the structure of benzoxazole and thiophene ring are firmly connected by chemical bonds. The benzoxazole ring is aromatic and the conjugated system is large, which endows the molecule with high stability. The thiophene ring is also an aromatic structure, and the two cooperate to make the 2,5-bis (benzoxazole-2-yl) thiophene chemically stable. Under normal temperature and pressure, it can tolerate common acids and bases and oxidative reducing agents, just like the ancient city, which is difficult to invade by foreign enemies.
However, under high temperature or strong oxidation and strong reduction environment, the stability will also be shaken. At high temperature, the intra-molecular energy increases, and the vibration of chemical bonds intensifies, such as the end of the strong crossbow, and the original stable structure may be destroyed. Strong oxidizing agents such as potassium permanganate can attack the region with high electron cloud density in the molecule, or cause the epoxidation of benzoxazole and thiophene to open the ring; strong reducing agents may change the electron cloud distribution on the ring, destroy the conjugated system, and the stability will be damaged.
Light stability is also key. This compound has a large conjugated system and strong light absorption capacity. Under light, the molecule absorbs photons and transitions to an excited state. Excited state activity is high, or triggers intramolecular rearrangement and photochemical reactions with substances in the environment. Long-term light, the molecular structure gradually changes, and the stability is not as good as before, just like the solar eclipse and the moon deficit, gradually wear out.
In terms of thermal stability, due to the interaction of intermolecular forces and conjugated systems, there is a certain degree of thermal stability. Moderate heating, the structure can be maintained; but the temperature is too high, exceeding its decomposition temperature, the intermolecular forces cannot be sustained, chemical bonds are broken, decomposed into small molecules, and the stability is lost, like a building falling, not the past.
In summary, 2,5-bis (benzoxazole-2-yl) thiophene has good stability under conventional conditions, but in extreme chemical, light, and thermal environments, the stability is easily challenged. When applying, it is necessary to consider the advantages and disadvantages according to the specific scene, and handle it with caution in order to avoid its harm.