As a leading 2-(4-hydroxyphenyl)-1-benzothiophene-6-ol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 2- (4-hydroxyphenyl) -1-benzothiophene-6-ol?
2-% 284-hydroxyphenyl% 29-1-benzothiophene-6-ol, its chemical structure is a kind of interesting organic compound structure. In this structure, the core is the benzothiophene ring, which is formed by fusing the benzene ring and the thiophene ring, and has unique chemical and physical properties.
At the second position of the benzothiophene ring, there is a (4-hydroxyphenyl) group connected. On this phenyl group, there is a hydroxyl group at the fourth position. The existence of this hydroxyl group endows the compound with certain hydrophilicity, and because the hydroxyl group has active chemical properties, it can participate in many chemical reactions, such as esterification, etherification, etc. < Br >
And in the 6-position of the benzothiophene ring, there is also a hydroxyl group. This 6-position hydroxyl group also has a significant impact on the properties of the compound, which can enhance the hydrogen bonding between molecules, and then affect the solubility, melting point and other physical properties of the compound. At the same time, this hydroxyl group is also an active check point in chemical reactions, and can undergo oxidation, substitution and other reactions.
Such structures are of great significance in organic synthesis, pharmaceutical chemistry and other fields. In organic synthesis, it can be used as a key intermediate to construct more complex organic molecules through various chemical reactions. In the field of medicinal chemistry, because of its unique structure or specific biological activities, such as anti-tumor, anti-inflammatory and other activities, it has become a hot research structural unit.
What are the main uses of 2- (4-hydroxyphenyl) -1-benzothiophene-6-ol
2-% 284-Hydroxyphenyl% 29-1-benzothiophene-6-ol, this is an organic compound with a wide range of uses.
In the field of medicine, it can be used as a key intermediate for drug synthesis. Today's medical research seeks compounds with specific biological activities to develop new drugs. The unique structure of this compound may give it the ability to interact with specific targets in organisms, such as participating in the inhibition of enzymes or the regulation of receptors, which in turn provides potential for the treatment of diseases. For example, in the development of some anti-cancer drugs, compounds with similar structures have been modified and optimized to exhibit inhibitory effects on the growth of cancer cells, and are expected to become an important part of new anti-cancer drugs.
In the field of materials science, it also has outstanding performance. With the advancement of science and technology, the demand for materials with special properties is increasing day by day. 2-% 284-hydroxyphenyl% 29-1-benzothiophene-6-ol may emerge in the field of optoelectronic materials due to its structural properties. For example, when preparing organic Light Emitting Diode (OLED), the compound may be used as a raw material for light-emitting layer materials. After rational design and processing, it endows OLED devices with unique luminous properties, such as higher luminous efficiency and better color purity, which contribute to the development of display technology.
In addition, in the field of organic synthesis chemistry, it is often used as an important building block. Chemists can modify and derive it through various chemical reactions to build more complex and diverse organic molecular structures. By changing its substituents or introducing other functional groups, the physical and chemical properties of compounds can be regulated to meet the application needs of different fields.
In summary, although 2-% 284-hydroxyphenyl% 29-1-benzothiophene-6-ol is an organic compound, it has great application potential in many fields such as medicine, materials science, and organic synthesis, and plays an indispensable role in promoting the development of various fields.
What are the synthesis methods of 2- (4-hydroxyphenyl) -1-benzothiophene-6-ol
2-% 284 - hydroxyphenyl% 29 - 1 - benzothiophene - 6 - ol, this is an organic compound. To make it, there are several common methods.
First, sulfur-containing aromatic compounds and phenolic compounds are used as starting materials. First, the sulfur-containing aromatic compound is subjected to a specific substitution reaction to introduce an active group that can react with phenolic compounds. For example, under appropriate reaction conditions, the benzothiophene derivative interacts with a halogenated reagent to introduce a halogen atom at a specific position to generate a halogenated benzothiophene derivative. This step requires careful selection of the reaction solvent and base, usually an aprotic solvent such as N, N-dimethylformamide (DMF) is appropriate, and the base can be selected from potassium carbonate, etc., to promote the smooth progress of the halogenation reaction.
Then, the prepared halogenated benzothiophene derivative and p-hydroxyphenol are coupled under palladium catalysis. In this process, palladium catalysts such as tetra (triphenylphosphine) palladium are indispensable, and appropriate ligands need to be added to improve the catalytic activity. At the same time, the control of reaction temperature and time is also very critical. Generally, the reaction temperature is maintained at a high level, about 80-120 ° C, and the reaction time ranges from several hours to ten hours, depending on the specific reaction process. Through this coupling reaction, the target product can be obtained from 2-% 284-hydroxyphenyl% 29-1-benzothiophene-6-ol.
Second, the strategy of gradually constructing benzothiophene rings can also be used. First, appropriate o-halogenated thiophenol and phenolic derivatives containing alkenyl groups are used as raw materials, and under the catalysis of bases and transition metals, an intramolecular cyclization reaction occurs to construct a benzothiophene skeleton. In this cyclization reaction, the base can be selected from potassium tert-butoxide, etc. Transition metal catalysts such as copper salts can effectively promote the reaction. The reaction conditions are mild or not, depending on the specific reactant structure. It is usually reacted at a relatively low temperature, such as 50-70 ° C, for a period of time to form a benzothiophene structure within the molecule. Then, the resulting product is hydroxylated to obtain the target product. The hydroxylation reaction can utilize appropriate hydroxylation reagents, such as hydrogen peroxide and other reagents under specific conditions, and the reaction conditions need to be controlled to ensure that the hydroxyl groups are accurately introduced into the target position.
All of the above methods require strict control of the reaction conditions during the experimental process, and fine treatment of the separation and purification steps after the reaction, in order to obtain high purity 2-% 284-hydroxyphenyl% 29-1-benzothiophene-6-ol.
What are the physical properties of 2- (4-hydroxyphenyl) -1-benzothiophene-6-ol
2-% 284-Hydroxyphenyl% 29-1-benzothiophene-6-ol, this substance is also in the field of chemistry and has unique physical properties.
Looking at its properties, under room temperature, or in the form of white to off-white crystalline powder. The cover is formed because its molecular structure contains specific atomic groups and chemical bonds, resulting in the orderly arrangement of particles. The powder is fine, uniform in texture, and has no obvious color and luster.
As for the melting point, it has been experimentally determined to be in a specific temperature range. Due to the strength and distribution of its intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., the molecule obtains enough energy at this temperature to break the lattice binding and convert from the solid state to the liquid state. This melting point is an important basis for the identification and purification of the substance.
In terms of solubility, it has a certain solubility in common organic solvents, such as ethanol and dichloromethane. Due to the interaction between the polarity of the molecule of the substance and the polarity of the solvent molecule, it follows the principle of "similar miscibility". In water, the solubility is relatively low, because the hydrophobic part of the molecule accounts for a large proportion, and the force between it and the water molecule is weak.
In addition, its density is also an important physical property. The value of density reflects the mass of the substance per unit volume and is related to the degree of molecular accumulation. Accurate determination of its density is helpful for accurate measurement and use of the substance in many practical application scenarios such as chemical production and preparation. The physical properties of 2-% 284-hydroxyphenyl-% 29-1-benzothiophene-6-ol, such as its properties, melting point, solubility, density, etc., are determined by its molecular structure and play a key role in the research, production and application of this substance.
What is the market outlook for 2- (4-hydroxyphenyl) -1-benzothiophene-6-ol?
Today, there are 2 - (4 -hydroxyphenyl) - 1 - benzothiophene - 6 - alcohols, which are organic compounds. Looking at its market prospects, it is really promising.
In the field of medicine, its prospects are quite good. Many studies have shown that such compounds containing benzothiophene structures may have unique biological activities. Taking other compounds with similar structures as an example, they may act on specific biological targets, such as key proteins involved in cell signaling pathways. Since the development of medicine, there is a growing demand for new therapeutic drugs. If 2- (4-hydroxyphenyl) - 1-benzothiophene-6-ol is deeply researched and developed, it may become a good medicine for specific diseases, such as some chronic diseases or difficult diseases. This will open up a wide world for it in the pharmaceutical market.
In the field of materials science, there is also potential. The structure of benzothiophene gives compounds unique photoelectric properties. Today, the demand for photoelectric materials is increasing, such as in the field of organic Light Emitting Diodes (OLEDs) and solar cells. If 2- (4-hydroxyphenyl) -1-benzothiophene-6-ol is reasonably modified and applied, it may improve the properties of photovoltaic materials, such as enhancing the luminous efficiency or improving the photoelectric conversion efficiency of solar cells, so as to occupy a place in the materials market.
However, its market development also faces challenges. Synthesis of the compound may be difficult, requiring fine processes and suitable reaction conditions, which may lead to rising production costs. And if it is to be applied in the fields of medicine or materials, a lot of experiments and tests are required to prove its safety and effectiveness. This process is time-consuming and laborious. However, over time, after unremitting research and overcoming difficulties, 2- (4-hydroxyphenyl) -1-benzothiophene-6-ol will surely shine in the market and contribute to human well-being and scientific and technological progress.