2-[(4-fluorophenyl)methyl]thiophene

2-%5B%284-fluorophenyl%29methyl%5Dthiophene, this is an organic compound, which can be called 2- [ (4-fluorophenyl) methyl] thiophene in Chinese. Its physical properties are of great research value, as detailed below.
Looking at its properties, under normal temperature and pressure, it is mostly in a liquid state. The color of this substance is usually colorless and transparent to light yellow, just like the shimmer of morning light, clear and slightly yellow.
When it comes to density, due to the fluorine atom and thiophene structure, its density is higher than that of most common organic solvents. If it is placed in a liquid, it seems to have a sinking potential, with a density of roughly 1.1-1.2 g/cm ³, but the exact value may vary slightly depending on the measurement conditions. The characteristics of the boiling point of
are also key. Due to the influence of the conjugated system and fluorine atoms in the molecule, its boiling point is relatively high, about 260-280 ° C. Just like the heat of cooking oil, it can be boiled and turned into a gaseous state.
In terms of melting point, although it is difficult to accurately predict due to the complex structure, it is usually about -10 ° C to 10 ° C, indicating that this compound can still maintain a liquid state in a relatively low temperature environment.
In terms of solubility, it is soluble in common organic solvents such as dichloromethane, chloroform, toluene, etc. Like a fish entering water, it can blend with these organic solvents, just like a like-minded friend, but its solubility in water is extremely low, just like the incompatibility of oil and water. This is because it is a non-polar organic molecule, and the force between water molecules is weak.
Volatility is relatively low. Due to the large force between molecules, it is not easy to volatilize at room temperature, just like a stable person, it is not easy to disperse.
Refractive index is also an important physical property. The refractive index measured under specific conditions may be a strong basis for identifying the purity and structure of this compound.
To sum up, the physical properties of 2 - [ (4 -fluorophenyl) methyl] thiophene are of great significance in the fields of organic synthesis and materials science, laying a solid foundation for its application and research.

2-% 5B% 284 - fluorophenyl%29methyl%5Dthiophene, Chinese name or 2 - [ (4 -fluorophenyl) methyl] thiophene. This is an organic compound with unique chemical properties and far-reaching influence on organic synthesis, materials science and other fields.
Looking at its structure, thiophene ring is connected to fluorophenyl methyl. Thiophene ring is aromatic, electron-rich, active in nature, and easy to lead electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Taking halogenation as an example, under specific conditions, halogen atoms can replace hydrogen atoms on thiophene rings. < Br >
The (4-fluorophenyl) methyl moiety connected to it has a strong electronegativity of fluorine atoms and an electron-absorbing induction effect, which can change the distribution of molecular electron clouds and affect the reactivity and selectivity. In the electrophilic substitution reaction, the presence of fluorine atoms may bias the reaction check point to a specific position of the thiophene ring.
In terms of physical properties, the compound may have a certain melting point, boiling point and solubility. Because it contains aromatic rings and polar fluorine atoms, it may have good solubility in organic solvents such as dichloromethane and chloroform, but poor solubility in water.
In the field of organic synthesis, 2- [ (4-fluorophenyl) methyl] thiophene is often used as a key intermediate, and complex organic molecular structures are constructed through various reactions. In materials science, due to its unique electronic structure and aromaticity, it may show potential in the preparation of organic optoelectronic materials, such as organic Light Emitting Diode (OLED) and organic solar cell materials.
Its chemical properties are determined by the structure, and it presents a variety of reactivity and properties in different reaction conditions and application scenarios, bringing many possibilities and challenges to the fields of organic synthesis and materials research.

2-%5B%284-fluorophenyl%29methyl%5Dthiophene, this is an organic compound with a wide range of application fields.
In the field of materials science, it is often used to create organic optoelectronic materials. Organic Light Emitting Diode (OLED) is an example. This compound can be used as a light-emitting layer material. With its unique molecular structure and electronic properties, it can efficiently convert electrical energy into light energy, and the emitted light is bright and has high color purity. It is also used in organic solar cells, which can improve the absorption of light and charge transfer efficiency of the battery, thereby enhancing the photoelectric conversion efficiency of the battery.
In the field of pharmaceutical chemistry, this compound may become a key intermediate for drug development due to its specific biological activity. Its unique chemical structure can interact with specific targets in organisms, such as certain enzymes or receptors, providing the possibility for the development of new drugs.
In the field of organic synthetic chemistry, 2-%5B%284-fluorophenyl%29methyl%5Dthiophene can be used as an important synthetic building block. Chemists can use various chemical reactions on it, such as substitution reactions, coupling reactions, etc., to construct more complex and functional organic molecules, expand the scope of organic synthesis, and help create new organic compounds.
In the fields of materials science, pharmaceutical chemistry and organic synthetic chemistry, 2-%5B%284-fluorophenyl%29methyl%5Dthiophene have shown important application value, promoting the continuous development and progress of various fields.

To prepare 2 - [ (4 - fluorophenyl) methyl] thiophene, there are various methods. Starting from thiophene, thiophene can be reacted with 4 - fluorobenzyl halide in an alkaline environment according to the method of nucleophilic substitution. Bases such as potassium carbonate, sodium carbonate, etc., the solvent can be acetonitrile, N, N - dimethylformamide, etc., heated and stirred, or it can be obtained.
Thiophene Grignard reagent can also be reacted with 4 - fluorobenzaldehyde to obtain the corresponding alcohol first, and then the target product can be obtained through dehydration and reduction steps. When making Grignard reagent, magnesium chips are reacted with halogenated thiophene in anhydrous ethyl ether or tetrahydrofuran. After the reaction with 4-fluorobenzaldehyde, the alcohol is treated with acid, then dehydrated with concentrated sulfuric acid, and finally reduced with lithium aluminum hydride.
The coupling reaction catalyzed by transition metals can be used. For example, thiophene boronic acid and 4-fluorobenzyl halide are reacted in a suitable solvent in the presence of transition metal catalysts and ligands such as palladium or nickel. Catalysts such as tetra (triphenylphosphine) palladium, ligands such as 2,2 '-bipyridine, etc., bases are also indispensable, and the reaction conditions need to be carefully regulated to obtain the ideal yield. < Br >
All methods have their own advantages and disadvantages. In actual operation, it should be carefully selected according to factors such as the availability of raw materials, cost, and difficulty of reaction conditions.

I have not obtained the exact price range of 2 - [ (4 - fluorophenyl) methyl] thiophene in the market. The price of this compound often varies due to a variety of factors.
First, the difficulty of preparing this compound has a great impact. If the preparation requires complicated steps, rare raw materials or special reaction conditions, the cost will be high and the price will rise accordingly. On the contrary, if the preparation process is relatively simple, the price may be slightly lower.
Second, market demand is also the key. If in a certain field, such as pharmaceutical research and development, materials science, etc., the demand for this compound is strong, and the supply is in short supply, the price will easily rise. If the demand is low, the supply exceeds the demand, and the price will fall.
Third, the source of supply also affects the price. If only a few suppliers can provide this compound, they may have more pricing power and the price may be higher. If there are many suppliers and the competition is fierce, the price is expected to be reduced due to competition.
In addition, the price level and transportation costs in different regions can also make the price vary. Therefore, in order to know the exact price range, it is necessary to consult the chemical product trading platform, consult the supplier or relevant industry experts to obtain an accurate number.