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What is the chemical structure of 2- (4-Fluorophenyl) -5- [ (5-iodo-2-methylphenyl) methyl] thiophene
2-%284-Fluorophenyl%29-5-%5B%285-iodo-2-methylphenyl%29methyl%5Dthiophene is the English name of the chemical substance, and 2- (4-fluorophenyl) -5- [ (5-iodine-2-methylphenyl) methyl] thiophene can be obtained by conversion. This compound consists of a thiophene ring as the core structure, with 4-fluorophenyl connected at the 2nd position of the thiophene ring and (5-iodine-2-methylphenyl) methyl connected at the 5th position.
Wherein, 4-fluorophenyl, that is, the benzene ring, has a fluorine atom located in the carbon para-position connected to the thiophene ring; (5-iodine-2-methylphenyl) methyl represents an iodine atom at the 5th position of the benzene ring, and a methyl group at the 2nd position. This benzene ring is then connected to the 5th position of the thiophene ring through This structure determines that the compound has unique chemical properties and reactivity, and may have important uses in the fields of organic synthesis, materials science, etc., because different substituents can participate in a variety of chemical reactions and can build new compounds or material systems.
What are the main uses of 2- (4-Fluorophenyl) -5- [ (5-iodo-2-methylphenyl) methyl] thiophene
2-%284-Fluorophenyl%29-5-%5B%285-iodo-2-methylphenyl%29methyl%5Dthiophene, this is the chemical name of an organic compound. Its naming follows specific chemical naming rules to accurately describe the molecular structure of the compound.
Such compounds have important uses in many fields. In the field of organic synthesis chemistry, they are often used as key intermediates. Organic synthesis aims to build complex organic molecules, and the unique structure of this compound can be transformed into other more complex molecular structures by chemical reactions, laying the foundation for the synthesis of organic materials with specific functions.
In the field of materials science, due to the structure of fluorine, iodine and other special atoms, the compound is endowed with unique physical and chemical properties. For example, the introduction of fluorine atoms can enhance the stability of compounds, change their solubility and surface properties, etc.; iodine atoms can affect the electron cloud distribution of molecules, which in turn affects the electrical properties of materials. Therefore, it can be used to develop new organic electronic materials, such as organic Light Emitting Diodes (OLEDs), organic solar cells, etc. OLEDs are widely used in the display field due to their self-luminous properties, lightness, wide viewing angle, and fast response speed. Organic solar cells are dedicated to achieving high-efficiency photoelectric conversion, providing a new way for the development of renewable energy.
In the field of medicinal chemistry, the structure of the compound may be compatible with some biological activity check points. By modifying and optimizing its structure, new drugs are expected to be developed. Because its specific structure may interact with specific proteins, enzymes and other targets in the organism, thereby regulating the physiological process in the organism and achieving the purpose of disease treatment.
In summary, although 2-%284-Fluorophenyl%29-5-%5B%285-iodo-2-methylphenyl%29methyl%5Dthiophene is a specific organic compound, it shows great application potential in many fields such as organic synthesis, materials science, medicinal chemistry, etc., and is crucial to promoting scientific research and technological development in related fields.
2- (4-Fluorophenyl) -5- [ (5-iodo-2-methylphenyl) methyl] thiophene
The preparation of 2- (4-fluorophenyl) -5- [ (5-iodo-2-methylphenyl) methyl] thiophene often involves a multi-step reaction. The first step may be to prepare an intermediate containing thiophene structure. The thiophene can be used as the starting material first, and a suitable substituent can be introduced at a specific position of the thiophene ring through a suitable electrophilic substitution reaction, so that it can be connected with other aryl groups later.
The second step, for the 4-fluorophenyl moiety, can be started from a derivative of 4-fluorobenzene. For example, 4-fluorobromobenzene is used as a raw material, and it is connected to the thiophene intermediate through a metal-catalyzed coupling reaction, such as Suzuki coupling or Stille coupling. Among them, suitable bases, ligands and catalysts need to be selected to improve the efficiency and selectivity of the reaction.
Furthermore, for the 5-iodine-2-methylphenyl methyl part, 2-methylbenzoic acid can be halogenated first, an iodine atom is introduced at the 5-position, and then reduced and halogenated to convert into the corresponding halogenated hydrocarbon. Afterwards, through nucleophilic substitution reaction, the halogenated hydrocarbon is connected to the above-mentioned thiophene intermediates that have been connected with 4-fluorophenyl, and the final product 2- (4-fluorophenyl) -5- [ (5-iodo-2-methylphenyl) methyl] thiophene is obtained.
During the reaction process, attention should be paid to the control of reaction conditions, such as temperature, reaction time, ratio of reactants, etc., which have important effects on the reaction yield and product purity. And after each step of the reaction, separation and purification operations, such as column chromatography, recrystallization, etc. are often required to obtain pure intermediates and final products.
What are the physical properties of 2- (4-Fluorophenyl) -5- [ (5-iodo-2-methylphenyl) methyl] thiophene
2-%284-Fluorophenyl%29-5-%5B%285-iodo-2-methylphenyl%29methyl%5Dthiophene, it is an organic compound. In terms of its physical properties, its appearance is usually solid, and the color is white to light yellow powder. This is due to the arrangement and interaction of atoms in the molecular structure, resulting in light reflection and absorption.
Looking at its melting point, it is about a certain temperature range. Due to the intermolecular forces, including van der Waals force, hydrogen bonds, etc., the molecules need to absorb specific energy before they can break free from the lattice binding and melt. The melting point of this compound can be an important basis for identification and purification.
As for solubility, it has a certain solubility in organic solvents, such as common chloroform and dichloromethane. Due to the fact that its molecular structure contains aromatic rings and sulfur atoms, it can form a similar and soluble interaction with organic solvent molecules. However, in water, its solubility is very small, because water is a strong polar solvent, and the polarity of the compound is relatively weak, the force between the two is difficult to overcome its own intermolecular force.
Its density is also one of the physical properties, because the mass and spatial arrangement of each atom in the molecule determine its unit volume mass. Although the exact value needs to be determined experimentally, the density range can be inferred from the structure and similar compounds.
In addition, the volatility of this compound is low, because of its strong intermolecular force, the molecule is not easy to leave the condensed phase and enter the gas phase. This property is very critical for storage and use, and can ensure its stability and safety.
In summary, the physical properties of 2-%284-Fluorophenyl%29-5-%5B%285-iodo-2-methylphenyl%29methyl%5Dthiophene are determined by their molecular structure, which is of great significance in chemical research and practical applications.
2- (4-Fluorophenyl) -5- [ (5-iodo-2-methylphenyl) methyl] thiophene
Today, there are 2- (4-fluorophenyl) -5- [ (5-iodine-2-methylphenyl) methyl] thiophene. Let me tell you in detail what the market prospect of this product is.
Looking at the current field of chemical industry and materials, the demand for fine chemicals is increasing. This compound contains special atoms such as fluorine and iodine, and its structure is unique, which has great potential in materials science, medicinal chemistry, etc.
In materials science, fluorine-containing groups can give materials special properties, such as hydrophobicity and weather resistance. This compound may be used to create new photoelectric materials, such as organic Light Emitting Diode (OLED) materials. With the rapid development of display technology today, the demand for OLEDs has increased sharply. If this compound can optimize the performance of OLEDs, improve luminous efficiency and prolong lifespan, its market prospect will be very broad.
As for pharmaceutical chemistry, halogen atoms can often change the biological activity and pharmacokinetic properties of compounds. The combination of 5-iodine-2-methylphenyl and thiophene may have unique pharmacological activities. If in-depth pharmacological research and screening are found to have curative effects on specific diseases, it will definitely attract the attention of pharmaceutical companies and open up new avenues for drug research and development. The market potential is immeasurable.
However, challenges need to be faced. Synthesis of this compound may be difficult and costly, which is not conducive to large-scale production and marketing activities. And the road to research and development of new materials and new drugs is long, requiring many experiments and strict approval.
But overall, 2- (4-fluorophenyl) -5- [ (5-iodine-2-methylphenyl) methyl] thiophene has a unique structure and potential opportunities in the field of materials and drugs. If the synthesis problem is overcome and the research and development challenges are properly addressed, it is expected to emerge in the market in the future and gain considerable benefits.