2 3 5 Tribromothiophene
quinoline thiophene imidazole thiazole

2,3,5-Tribromothiophene

Taiy Chemical

Specifications

HS Code

128763

Chemical Formula C4HBr3S
Molar Mass 314.72 g/mol
Appearance Off - white to light yellow solid
Melting Point 86 - 88 °C
Boiling Point 273 - 275 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Purity Typically available in high purity grades e.g., 97%+
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General Information
Frequently Asked Questions
What are the main uses of 2,3,5-tribromothiophene?
2% 2C3% 2C5-tribromobenzoic acid, although this substance did not have its name in ancient times, it can also be used in order to understand the needs of ancient times.
In the field of medicine, ancient healers often sought golden stones and plants to treat diseases. If 2% 2C3% 2C5-tribromobenzoic acid existed at that time, or because of its specific chemical properties, it can be used for disinfection and antiseptic. Ancient sores were swollen and poisonous, and were easily attacked by evil poison and caused to ulcerate. This medicine may be able to apply to the affected area with its antibacterial properties, inhibit the growth of evil poison, and help the wound to converge and heal.
In the dyeing and weaving industry, ancient dyers used natural dyes as fabrics to add color. 2% 2C3% 2C5-tribromobenzoic acid can be used as a mordant to better attach the auxiliary dye to the fabric fibers. Ancient fabrics desire bright and long-lasting colors, and mordants are very important, which can make the color last for a long time, not easy to fade, and satisfy the pursuit of gorgeous clothes by dignitaries.
Furthermore, in the art of alchemy, alchemists want to refine the elixir of immortality, often using various gold and stone medicines as raw materials. 2% 2C3% 2C5-tribromobenzoic acid, or because of its chemical activity, participates in some complex chemical reactions and changes the properties and efficacy of the elixir. Although its purpose is absurd, from a chemical point of view, it can be regarded as an exploration attempt.
Although the ancient books did not contain the name 2% 2C3% 2C5-tribromobenzoic acid, today's scientific understanding has been used to infer different fields in ancient times, or to have the above potential uses, to help the ancients cope with the needs of life, production and exploration of the unknown.
What are the physical properties of 2,3,5-tribromothiophene?
2% 2C3% 2C5 -tribromopyridol is an organic compound with unique physical properties.
Looking at its appearance, it often takes the shape of white to light yellow crystalline powder. This color state is distinct and easy to identify.
When it comes to the melting point, it is about 150-152 ° C. The melting point is a key physical property of a substance. This value indicates that the substance will undergo a phase transition from solid to liquid in a specific temperature range, reflecting the strength of its intermolecular forces.
In terms of boiling point, it is about 363.7 ° C. The boiling point reveals the temperature conditions required for a substance to transform from a liquid state to a gaseous state, reflecting the difficulty of molecules breaking free from each other and entering the gas phase. From this, it can be known that the substance will only boil and vaporize at relatively high temperatures.
Solubility is also an important physical property. It is slightly soluble in water, but soluble in common organic solvents such as ethanol, acetone, chloroform, etc. This difference in solubility is due to the difference in the polarity characteristics of the molecules of the substance and the interaction between water molecules and organic solvent molecules. Due to the weak force between the molecular structure and water molecules, it is difficult to dissolve in water; while it can form a good interaction with organic solvent molecules, so it is easily soluble in organic solvents. The density of
is usually around 2.2-2.4 g/cm ³. This value indicates that the density of this substance is higher than that of common substances such as water. In practical application scenarios such as mixing and separation of substances, the density property is of important guiding significance.
2% 2C3% 2C5 -tribromopyridinol These physical properties have laid the foundation for its application in many fields such as chemical industry and materials. People choose its use method, processing technology and separation and purification methods based on its melting point, boiling point, solubility, density and other properties.
What are the chemical properties of 2,3,5-tribromothiophene?
2% 2C3% 2C5-tribromopyridine is an important intermediate in organic synthesis. Its chemical properties are unique and it has a wide range of uses.
The appearance of this substance is white to light yellow crystalline powder, which is relatively stable at room temperature and pressure. However, it is very easy to burn when exposed to open flames and hot topics, so it is necessary to strictly prevent ignition sources when storing and using it.
In terms of chemical activity, the presence of bromine atoms in the molecule makes it have good electrophilic substitution activity. In many organic reactions, bromine atoms can be used as leaving groups to participate in coupling reactions, such as Suzuki reaction and Heck reaction. Through these reactions, various functional groups can be easily introduced into the pyridine ring, thereby synthesizing organic compounds with rich and diverse structures.
2% 2C3% 2C5-tribromopyridine also has certain hazards to water. If it flows into the aquatic environment, it may cause adverse effects on aquatic organisms. Therefore, in the process of production and use, it is necessary to properly treat wastewater containing this substance to avoid pollution to the environment.
In addition, its solubility is slightly soluble in water, but soluble in some organic solvents, such as dichloromethane, chloroform, etc. This solubility characteristic provides convenience for its operation in organic synthesis, and it can be dissolved, reacted, separated and purified with the help of suitable organic solvents.
In conclusion, 2% 2C3% 2C5-tribromopyridine plays a key role in the field of organic synthesis due to its unique chemical properties. However, its safety and environmental impact should also be fully considered when using and handling it.
What are the synthesis methods of 2,3,5-tribromothiophene?
2%2C3%2C5-%E4%B8%89%E6%BA%B4%E5%99%BB%E5%90%A9%E7%9A%84%E5%90%88%E6%88%90%E6%96%B9%E6%B3%95%E6%9C%89%E4%B8%8B%E5%88%97%E4%B8%89%E7%A7%8D%EF%BC%9A
1. ** Claisen condensation reaction method **: Using the corresponding ester as raw material, under the action of strong base, Claisen condensation reaction occurs. For example, ethyl acetate can self-condensate to form ethyl acetoacetate under the action of sodium ethanol. Then through a specific substitution reaction, different substituents are introduced into the α-carbon of ethyl acetoacetate, corresponding to the substitution of 2-position, 3-position and 5-position respectively. After hydrolysis, decarboxylation and other steps, 2% 2C3% 2C5-tribromo indirubin can be prepared. This reaction needs to pay attention to the control of reaction conditions. The amount of strong base and reaction temperature have a great impact on the formation and purity of the product.
2. ** Fourier-gram reaction method **: The Fourier-gram alkylation or Fourier-gram acylation reaction of aromatics and halogenated hydrocarbons catalyzed by Lewis acid. First, the basic skeleton is constructed by the Fourier-gram reaction with a suitable aromatic hydrocarbon as the starting material, and then the bromine atom is introduced at a specific position by the bromination reaction. For example, the Fourier-gram acylation of benzene is first carried out to obtain acetophenone derivatives. After bromination, bromine atoms are selectively introduced at the 2% 2C3% 2C5-position, and further converted into the target product 2% 2C3% 2C5-tribromoindirubin through a series of reactions. In the reaction process, the type and dosage of Lewis acid and the choice of brominating reagent are the key, which will affect the selectivity and yield of the reaction.
3. ** Diazotization reaction method **: For compounds containing amino groups, the diazotization reaction is carried out first. The precursor compound containing amino groups and suitable structure is reacted with sodium nitrite at low temperature and strong acid conditions to form a diazonium salt. The diazonium salt is active in nature and can be reacted with different nucleophiles to introduce bromine atoms at specific positions to construct the structure of 2% 2C3% 2C5 -tribromo indirubin. In this method, the temperature control of the diazotization reaction is extremely important. If the temperature is too high, the diazoite is easy to decompose, which affects the subsequent reaction and product formation.
What are the precautions for storing and transporting 2,3,5-tribromothiophene?
2% 2C3% 2C5-tribromopyridine is a valuable and special-purpose chemical. When storing and transporting, pay attention to the following things:
First, the storage place must be dry and cool. This chemical is highly susceptible to moisture. Once it is damp, it may cause quality deterioration and even cause chemical reactions. As the ancient saying goes: "Water is the source of all things, and it is also the beginning of all things to decay." Humid environment is just like water erosion, which has a great impact on the quality of 2% 2C3% 2C5-tribromopyridine. Therefore, it should be well ventilated, dry and moisture-free, and placed in a sealed container to prevent moisture from invading.
Second, keep away from fire and heat sources. This chemical may be in danger of burning or exploding in case of hot topics or open flames. The old saying: "A spark can start a prairie fire." Although 2% 2C3% 2C5-tribromopyridine is non-flammable, it can also cause accidents in case of hot topics and open flames. Therefore, fireworks should be strictly prohibited in the storage place, and it should be kept away from high temperature equipment and heat sources.
Third, when transporting, be sure to ensure that the packaging is intact. If the packaging is damaged, chemicals may leak out, which will not only stain the environment, but also endanger the safety of transporters. Gu Youyun: "The embankment of a thousand miles is destroyed in the ant nest." Minor damage to the packaging may also cause serious disasters. During transportation, it should be handled with care to avoid violent vibrations and collisions to prevent damage to the packaging.
Fourth, it should be stored and transported separately from other chemicals. 2% 2C3% 2C5-tribromopyridine or adverse reactions with certain chemicals cause danger. Like the ancient generals, each has its own division and cannot be confused. Different chemicals should also be stored and transported in categories to prevent contact with each other and cause danger.
Fifth, storage and transportation personnel must undergo professional training. Familiar with the characteristics, hazards and emergency treatment methods of 2% 2C3% 2C5-tribromopyridine, you can deal with emergencies. The ancients said: "If you want to do a good job, you must first use your tools." Professional training of personnel, such as sharp weapons in hand, can better ensure the safety of storage and transportation.