2 3 4 Tribromothiophene
quinoline thiophene imidazole thiazole

2,3,4-Tribromothiophene

Taiy Chemical

Specifications

HS Code

876638

Chemical Formula C4HBr3S
Molar Mass 314.72 g/mol
Appearance Solid
Color Yellowish
Melting Point 93 - 96 °C
Boiling Point 265 - 267 °C
Density 2.59 g/cm³
Solubility Insoluble in water, soluble in organic solvents like ethanol, ether
Odor Faint, characteristic
Stability Stable under normal conditions
Flash Point 114.3 °C
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General Information
Frequently Asked Questions
What are the physical properties of 2,3,4-tribromothiophene?
2%2C3%2C4-%E4%B8%89%E6%BA%B4%E5%99%BB%E5%90%A9%E8%80%85 is an organic compound. Its physical properties are quite unique, and I would like to describe them in detail.
Looking at its shape, under room temperature and pressure, it 2%2C3%2C4-%E4%B8%89%E6%BA%B4%E5%99%BB%E5%90%A9%E7%A1%AE a solid state. Its color is white as snow, just like the snow that falls at the beginning of winter, pure and free of variegated colors, giving people a feeling of freshness.
As for the melting point, it is about [X] ° C. This temperature is just like a limit. When the ambient temperature reaches this value, the substance will be like ice in the warm sun, gradually melting from solid to liquid, and the shape change is very wonderful. The boiling point is around [X] ° C. If the temperature continues to rise to this point, it will turn into a curling vapor and rise in the air, showing the wonder of the transformation of the three states of matter.
In terms of solubility, 2%2C3%2C4-%E4%B8%89%E6%BA%B4%E5%99%BB%E5%90%A9 in organic solvents, such as ethanol, ether, etc., it is quite soluble, just like salt fused into water, invisible but real. However, in water, its solubility is very small, like oil and water, it is difficult to blend, and this property is related to the hydrophobicity of its molecular structure.
Above the density, 2%2C3%2C4-%E4%B8%89%E6%BA%B4%E5%99%BB%E5%90%A9 density is slightly larger than that of water. If it is placed in water, it is like a stone sinking to the bottom of the water, slowly sinking, showing its relatively heavy mass.
Furthermore, its smell is weak, if it is not deliberately close to sniff, it is almost invisible. And under normal conditions, this substance is quite stable, and it is not easy to react violently with common substances. It is like a calm person and is not easily moved by the outside world.
All these physical properties are of great significance in many fields such as chemical industry and medicine, laying the foundation for related research and application.
What are the chemical properties of 2,3,4-tribromothiophene?
2%2C3%2C4-%E4%B8%89%E6%BA%B4%E5%99%BB%E5%90%A9%E8%80%85, chemical properties are very special. It is oxidizing and can combine with many original substances. In case of gold, it can often be oxidized to form gold compounds. This process is like melting gold in a fire. Under the action of its force, the properties of gold can be quietly changed.
Furthermore, 2%2C3%2C4-%E4%B8%89%E6%BA%B4%E5%99%BB%E5%90%A9%E5%9C%A8 specific components, it can generate hydrolytic reactions. This reaction is like a spring rain. It can change its own properties and decompose other components.
In the field of synthesis, 2%2C3%2C4-%E4%B8%89%E6%BA%B4%E5%99%BB%E5%90%A9 is also often used as an important function. It can generate multiple chemical reactions, or additions, or substitutions, and generate new chemical compounds. Just like a craftsman with his tools, he can carve beautiful molecular products.
When they meet, they can also generate neutralization and reaction. This square interaction, like the, can form a new equilibrium of transformation, generating phase and water.
, the 2%2C3%2C4-%E4%B8%89%E6%BA%B4%E5%99%BB%E5%90%A9 of transformation is rich and rich, and it plays an important role in the world of transformation. It plays an important role in the aspects of diversification, reaction and workmanship.
What are the common synthesis methods of 2,3,4-tribromothiophene?
2%2C3%2C4-%E4%B8%89%E6%BA%B4%E5%99%BB%E5%90%A9%E7%9A%84%E5%90%88%E6%88%90%E6%96%B9%E6%B3%95%E5%B8%B8%E8%A7%81%E6%9C%89%E4%B8%8B%E5%88%97%E4%B8%89%E7%A7%8D%EF%BC%9A
** 1. Using diethyl malonate as raw material **
1. ** The first step **: diethyl malonate reacts with halogenated ethane under the action of sodium alcohol, which is a nucleophilic substitution reaction. Sodium alcohol takes away hydrogen on the methylene in diethyl malonate to form a carbon negative ion, which attacks the alpha-carbon atom of halogenated ethane, and the halogen atom leaves to form ethyl-substituted diethyl malonate.
2. ** The second step **: The resulting product reacts with halogenated propane under the action of sodium alcohol, which is also nucleophilic substitution, and then introduces propyl.
3. ** The third step **: The product after two substitutions is hydrolyzed. Under acidic conditions, the ester group is hydrolyzed to a carboxyl group. Subsequently, decarboxylation is heated. Since the malonic acid-type compound is easily decarboxylated by heat, 2% 2C3% 2C4 -trimethylvaleric acid is finally generated.
** Second, ethyl acetoacetate is used as raw material **
1. ** First step **: Ethyl acetoacetate reacts with halogenated ethane under the action of sodium alcohol. Sodium alcohol causes the methylene of ethyl acetoacetate to form a carbon negative ion, and the carbon negative ion undergoes nucleophilic substitution with halogenated ethane, and ethyl is introduced.
2. ** The second step **: The product is then reacted with halopropane under the action of sodium alcohol, and the propyl group is introduced again by nucleophilic substitution.
3. ** The third step **: First perform keto decomposition, that is, under the condition of dilute alkali, the ester group is hydrolyzed, then acidified, and then heated to decarboxylate. Due to the decarboxylate of acetoacetic acid-type compounds under specific conditions, the final target product can be generated 2% 2C3% 2C4 -trimethylvaleric acid.
* III. Using Grignard reagent as raw material **
1. ** FIRST STEP **: Preparation of isopropyl Grignard reagent. For example, isopropyl halide is reacted with magnesium in anhydrous ether to form isopropyl magnesium halide.
2. ** SECOND STEP **: Reaction with acetaldehyde with isopropyl Grignard reagent. The negatively charged carbon in the Grignard reagent attacks the carbonyl carbon of acetaldehyde, forms a new carbon-carbon bond, and generates the corresponding alcohol.
3. ** SECOND STEP **: Oxidation of the resulting alcohol to ketones, using a suitable oxidizing agent such as chromic acid, etc.
4. ** SECOND STEP **: Preparation of methyl Grignard reagent again. Let the methyl Grignard reagent react with the above-mentioned ketones and introduce methyl. The fifth step is to oxidize the product to a carboxyl group to obtain 2% 2C3% 2C4-trimethylvaleric acid.
In which fields is 2,3,4-tribromothiophene used?
2% 2C3% 2C4-tribromobenzoic acid has a wide range of uses. In the field of medicine, it can be used as a key raw material of traditional Chinese medicine. With its special chemical structure, it can participate in the synthesis of various drugs, helping to improve the efficacy and stability of drugs. In the chemical industry, it is an indispensable ingredient for the synthesis of special materials. After special processing, it can give the material unique properties, such as better oxidation resistance or corrosion resistance. In the agricultural field, it can be used as a pesticide synergist, added to pesticide formulations to improve the control effect of pesticides on pests, and at the same time reduce the amount of pesticides used to reduce the impact on the environment.
According to Guanfu's "Tiangong Kaiwu", although the compound was not described in detail at that time, the concept of "Tiangong Kaiwu, shape with matter" advocated in the book is also enlightening to explore the application of 2% 2C3% 2C4-tribromobenzoic acid today. It uses natural things, through ingenuity and craftsmanship, to exert endless functions. Today's research and application of 2% 2C3% 2C4-tribromobenzoic acid also follows this path, gaining insight into its characteristics, and exploring its potential in various fields such as medicine, chemical industry, and agriculture, in order to meet the needs of everyone for health, material properties, and agricultural production, so as to make the best use of things and benefit the world.
What is the approximate market price of 2,3,4-tribromothiophene?
In today's market, the price of 2,3,4-trichlorobenzoic acid is roughly variable, and varies with the supply and demand of the market and the amount of production.
Looking at the market conditions, if the supply of goods is sufficient and the seekers are not prosperous, the price may be cheap, or tens of dollars per catty. At this time, if the producers want to sell their goods quickly, they dare not raise their prices, for fear of being stuck in the market, the price will be flat.
However, if there is a shortage of supply, and there are many seekers, the price will rise. Or due to the scarcity of raw materials, or the difficulty of making them, the production is insufficient, and the price per catty may jump to more than 100 yuan, which is also unknown.
And its price is also subject to quality. The good quality of 2,3,4-trichlorobenzoic acid, with few impurities and high purity, is good for both workers and farmers. People in the city compete to buy it, and the price rises accordingly.
Also, the difference in region is also the reason for the price change. In the big port of the city, merchants converge, the circulation of goods is convenient, and the price may be relatively easy. In remote places, transportation is difficult, and taxes and fees are added, so the price will increase.
In short, the market price of 2,3,4-trichlorobenzoic acid can range from tens of dollars per catty to more than 100 dollars per catty. It is difficult to have a fixed number. It is necessary to observe the facts of the city before you can know its approximate price.