1 5 Bromo 2 Methylphenyl Methyl 5 4 Fluorophenyl Thiophene
quinoline thiophene imidazole thiazole

1-[(5-Bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)-Thiophene

Taiy Chemical

Specifications

HS Code

815731

Chemical Formula C18H14BrFS
Molecular Weight 361.27
Appearance Solid (predicted)
Boiling Point Predicted to be in a certain range based on similar compounds
Melting Point Predicted value based on structure
Solubility In Water Low (due to non - polar nature of the molecule)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Density Predicted density value
Flash Point Predicted flash point for safety considerations
Vapor Pressure Low vapor pressure as it's a solid - like compound
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General Information
Frequently Asked Questions
What is the main use of 1- [ (5-bromo-2-methylphenyl) methyl] -5- (4-fluorophenyl) thiophene?
1 - [ (5-hydroxy- 2-methylbenzyl) methyl] - 5 - (4-bromobenzyl) imidazole, this is a class of organic compounds. Its main uses are quite extensive. From the perspective of "Tiangong Kaiji", it can be described from the fields of chemical preparation and pharmaceutical research and development.
In chemical preparation, such compounds can be used as important intermediates in organic synthesis. With their special chemical structure, they can go through a series of chemical reactions to construct more complex organic molecular structures. For example, in the preparation process of fine chemical products, with the help of their structural characteristics, they can participate in various condensation, substitution and other reactions, laying the foundation for the synthesis of chemical materials with specific functions, just like the processing and transformation of various raw materials in "Tiangong Kaiwu". This compound is also a key link in the chemical synthesis chain. After ingenious "processing", substances with various functions are derived.
In the field of pharmaceutical research and development, this compound shows potential medicinal value. Because its structure can interact with specific targets in organisms, it may have the effect of regulating physiological functions and treating diseases. For example, Xingli modifies its structure to enhance its affinity for specific disease-related proteins, so as to develop new therapeutic drugs. Just like the mining and utilization of various material properties in "Tiangong Kaiwu", this compound is also used in pharmaceutical research and development to find a way to cure diseases and save people based on its structural properties. However, the specific medicinal efficacy still needs to be verified by in-depth pharmacological research and clinical trials.
What are the physical properties of 1- [ (5-bromo-2-methylphenyl) methyl] -5- (4-fluorophenyl) thiophene
The physical properties of 5-hydroxy- 2-methylfuranomethyl and 4-enofuranohydrazide are different, and each shows its own state.
5-hydroxy- 2-methylfuranomethyl has the properties of alcohol hydroxyl groups, which can react with active metals such as sodium to replace and release hydrogen. Because of its furan ring, it is aromatic and more stable than ordinary aliphatic compounds. There is also the substitution of methyl and hydroxyl groups, which makes the molecular polarity change and has good solubility in organic solvents, but the solubility in water varies depending on the specific situation. The presence of hydroxyl groups also makes it possible to participate in the esterification reaction and co-heat with organic acids or inorganic anhydrides to form corresponding esters.
As for 4-enofuranoyl hydrazide, due to the carbon-carbon double bond, an addition reaction can occur. In case of bromine water, the double bond is broken, and bromine atoms are added to both ends of the double bond, causing the bromine water to fade; under the action of hydrogen in the catalyst, it can be added to form saturated derivatives. Its hydrazide structure, with some of the characteristics of amides, can be hydrolyzed. Under the catalysis of acids or bases, the amide bond is broken to form corresponding acids and hydrazines. And it has a certain coordination ability and can complex with metal ions to form complexes with unique structures. This property may have applications in many fields such as materials science and biomedicine. < Br >
Both are due to the existence of furan rings, which have certain stability and special electron cloud distribution. They are important structural units in the fields of organic synthesis and drug research and development. Due to their unique physical and chemical properties, they can derive many compounds with special functions.
What is the synthesis method of 1- [ (5-bromo-2-methylphenyl) methyl] -5- (4-fluorophenyl) thiophene
To prepare 1 - [ (5 - hydroxyl - 2 - methylbenzyl) methyl] - 5 - (4 - bromobenzyl) imidazole, the following ancient method can be used.
First take the appropriate raw materials, in which about the (5 - hydroxyl - 2 - methylbenzyl) methyl part, can find the corresponding benzyl compound containing hydroxyl and methyl, through a specific reaction, methylation to obtain (5 - hydroxyl - 2 - methylbenzyl) methyl intermediate. This process requires attention to the reaction conditions, such as temperature, catalyst dosage, etc. If the temperature is too high or too low, it may affect the rate of the reaction and the purity of the product; improper amount of catalyst will also make the reaction deviate from expectations.
For the 5- (4-bromobenzyl) part, select the appropriate bromine-containing raw material and benzyl derivative, and through clever reaction, connect the bromine atom to the benzyl group to form the 5- (4-bromobenzyl) intermediate. In this step, the ratio of raw materials is extremely critical. If the ratio is unbalanced, impurities will easily form and affect the subsequent reaction.
Then, the above two carefully prepared intermediates are mixed in a suitable solvent, and specific reagents are added to promote the reaction between the two, and then the target product 1- [ (5-hydroxy- 2-methylbenzyl) methyl] -5- (4-bromobenzyl) imidazole is generated. During the reaction, the progress of the reaction should be closely observed by means such as thin-layer chromatography. After the reaction is completed, the impurities are removed by separation and purification to obtain a pure product. The separation process may require the use of extraction, column chromatography and other techniques. When purifying, attention should be paid to the fine operation to prevent product loss or the introduction of new impurities. In this way, the desired compound can be obtained.
What is the market price of 1- [ (5-bromo-2-methylphenyl) methyl] -5- (4-fluorophenyl) thiophene?
Looking at this question, it is necessary to inquire about the price of (1- [ (5-hydroxy- 2-methylbenzyl) methyl] -5- (4-fluorobenzyl) imidazole) in the market. However, it is not easy to clarify its price, and its price is affected by many factors.
The first one to bear the brunt is its quality. If the purity of the material is extremely high, the impurities are almost none, the craftsmanship is exquisite, and the quality is high, its price must be high. On the contrary, if the quality is slightly inferior and contains some impurities, which affects its performance, the price should be low.
Furthermore, the state of supply and demand is also the key. If the market demand for this product is surging, and the supply is limited, the supply is in short supply, and the price will skyrocket. However, if the market demand is weak, the production is excessive, and the supply exceeds the demand, the price will inevitably decline.
The difference in origin also has an impact. Different origins have different production costs due to different raw material costs, labor costs, transportation conditions, etc., resulting in different prices.
In addition, the difficulty of preparation is also related to the price. If the preparation process requires complicated processes, rare raw materials, or extremely high equipment and technical requirements, the cost will be high, and the price will also rise.
According to the concept of "Tiangong Kaiwu", the price of all things is determined by the difficulty of production, the situation of supply and demand, and many other factors. Although it is difficult for me to confirm the exact price of (1- [ (5-hydroxy- 2-methylbenzyl) methyl] -5- (4-fluorobenzyl) imidazole) in the current market, if you want to know the price, you can consult the chemical raw material market merchants, relevant trade platforms, or professional chemical consulting institutions to get accurate prices.
What are the manufacturers of 1- [ (5-Bromo-2-methylphenyl) methyl] -5- (4-fluorophenyl) thiophene?
Looking at what you said, I seem to be exploring the manufacturer of a specific compound. However, the expressions " (5-hydroxy- 2-methylbenzyl) methyl" and " (4-ethylbenzyl) piperidine" involved are quite professional and obscure.
In the land of China, there were many experts who were skilled in alchemy and medicine in the past, or had been involved in the related research of such compounds. However, at that time, the ancient books were mostly written in obscure words and mysterious words, and it was not easy to find the traces of the manufacturers of these compounds accurately.
Or among the skills and products recorded in "Tiangong Kaiwu", it is also difficult to find clear records of the manufacturers of these compounds. Because of the ancient chemical techniques, they were mostly scattered in folk workshops and secret alchemy rooms, and the inheritance methods were mostly taught by mouth and heart, and were rarely widely distributed in Ming.
And the production at that time, or its practical effect, rather than today's commercial promotion, so even if there is someone who can make this thing, it may not be famous in the world. Even if there are two or two parties who know it, they may not seek a unique secret, hide its method, and not let outsiders know.
Although I try my best to think about it, it is difficult to specify the exact manufacturer of these compounds. You may need to visit the hermits in the deep mountains and old forests, and study ancient Confucianism, or you may be able to get one or two clues.