What is the chemical structure of α-mercapto-2-thiophene acetic acid?
Alas! The alpha-alkynyl-2-pentanoic acid you are inquiring about is a unique compound in organic chemistry. Its chemical structure is very interesting, composed of a clever combination of alpha-alkynyl, carbonyl and carboxyl groups.
Looking at its structure, the alpha-alkynyl group, a group containing carbon-carbon three bonds, endows this compound with active chemical properties. The high degree of unsaturation of alkynyl groups makes it easy for molecules to participate in various addition, cyclization and other reactions, just like a hero with stunts, crisscrossing the rivers and lakes of chemical reactions.
Furthermore, the 2-pentanoic acid part, the carbonyl group is the logo of the ketone, and has a unique nucleophilic addition activity. The carboxyl group makes the compound both acidic and can participate in acid-base reactions. The coexistence of the two makes the molecular properties more abundant.
When the α-alkynyl group is connected to the 2-pentanoic acid and affects each other, the electronic effect of the alkynyl group acts on the carbonyl group and the carboxyl group, making its reactivity different from that when it exists alone. Or make the carbonyl group more vulnerable to nucleophilic attack, or change the acidity of the carboxyl group.
Such a chemical structure determines its wide use in the field of organic synthesis. It can be used as a key intermediate to build complex organic molecules through ingenious reaction pathways, just like building a magnificent castle. This is one of the cornerstones. Chemists can design and implement various reactions according to their structural characteristics, expanding the boundaries of organic chemistry, and contributing to the development of new drugs and materials.
What are the main uses of α-mercapto-2-thiophene acetic acid?
Alpha-carboxyl-2-aminobutyric acid has many main uses. This substance has significant efficacy in the field of medicine. It can help pharmacies synthesize various drugs to treat various diseases. For example, some of the drugs involved in the synthesis can be used to regulate human metabolism, balance the functions of the viscera, and are beneficial to diseases that are not smooth in qi and blood and violate the harmony of the viscera.
In biochemical research, α-carboxyl-2-aminobutyric acid is also a key thing. Scholars often use it to explore the chemical reactions in living organisms and clarify the mechanism of life activities. Due to its unique chemical structure, it plays an important role in many biochemical reactions, which can help researchers gain insight into the mysteries of life, such as the metabolic pathway of cells and the transmission mechanism of signals. Furthermore, in the food industry, it can also be seen. It can be used as a food additive to improve the flavor and texture of food. Adding it to food can make the taste of food more mellow and taste more delicious, satisfying everyone's pursuit of food.
In the field of agriculture, α-carboxyl-2-aminobutyric acid can also play a role. Applied to crops, it can promote their growth and development, enhance the resilience of crops, enable them to thrive in harsh environments, and ensure abundant harvests. Or it can optimize the soil micro-ecological environment, make the soil fresh, and contribute to the sustainable development of agriculture.
It can be seen that α-carboxyl-2-aminobutyric acid plays an indispensable role in many fields such as medicine, biochemistry, food, agriculture, etc. It has a wide range of uses and far-reaching impact.
What are the physical properties of α-mercapto-2-thiophene acetic acid?
Alpha-differential-2-butanoic acid, also known as acetyllactic acid, is an organic compound. Its physical properties are unique. Under normal temperature and pressure, it is colorless to pale yellow liquid, or a crystalline solid. This form is affected by the ambient temperature and purity.
Its solubility is soluble in water, and it also shows good solubility in many organic solvents such as ethanol and ether. This property makes it able to be used as an intermediate in chemical reactions and industrial processes, and can flexibly switch between aqueous and organic phases to participate in the reaction.
Its melting point is in a specific range, generally about 135-139 ° C, and the exact value of the melting point fluctuates due to the presence of impurities. The melting point characteristic is of great significance in the separation and purification process. With the help of temperature control, the effective separation of α-differential-2-butanoic acid can be achieved to ensure the purity of the product.
In terms of boiling point, it is roughly 210-212 ° C. The existence of boiling point indicates that at the corresponding temperature, α-differential-2-butanoic acid will change from liquid to gaseous state. This property is used in operations such as distillation to provide a key basis for the separation and purification of the substance.
α-differential-2-butanoic acid has hygroscopicity and is easy to absorb moisture from the air. This property requires special attention to the ambient humidity during storage, and should be stored in a dry place to prevent it from affecting the quality and stability due to moisture absorption, or even triggering a chemical reaction that alters its chemical structure and properties.
What are the synthesis methods of α-mercapto-2-thiophene acetic acid?
To prepare α-diethyl-2-butanoic acid, there are three methods.
One is to start with acetaldehyde and diethyl oxalate. First, acetaldehyde and diethyl oxalate are condensed under the catalysis of sodium alcohol. Diethyl oxalate has good carbonyl activity, and the α-hydrogen of acetaldehyde has a certain acidity. Under the action of sodium alcohol, the α-carbon negative ion of acetaldehyde is formed, which then attacks the carbonyl nucleophilic of diethyl oxalate to obtain an intermediate product. Subsequent steps of hydrolysis and decarboxylation can obtain α-diethyl-2-butanoic acid. During hydrolysis, the ester group is converted into a carboxyl group, and the decarboxylation process prompts the decarboxylation of carbon dioxide from the carboxyl group due to the specific structure, and the final target product is obtained.
Second, ethyl acetoacetate can be started. Ethyl acetoacetate acts as a strong base, and α-hydrogen is taken away to form a carbon negative ion. After reacting with ethyl chloroacetate, the carbon negative ion replaces the carbonyl carbon nucleophilic of ethyl chloroacetate and introduces a carboxyl-containing side chain. After hydrolysis, acidification and decarboxylation operations. Hydrolysis causes the ester group to form a carboxyl group, and acidification adjusts the pH of the system. The decarboxylation reaction takes advantage of the characteristic that β-ketoacid is easily decarboxylated when heated to achieve the synthesis of α-
Third, pyruvate is used as raw material. Under specific conditions, pyruvate can be reduced to hydroxyl groups by reduction reaction to obtain lactic acid intermediates. After that, the hydroxyl groups in lactic acid are appropriately substituted and activated, and then acetyl groups are introduced. For example, the hydroxyl groups are converted into easy-to-leave groups and reacted with acetylation reagents to introduce acetyl groups. Finally, after oxidation and other steps, the functional groups are adjusted to obtain α-hydro- 2-butanoic acid. This process requires precise control of the reaction conditions and the degree of reaction in each step to achieve higher yield and purity.
What is the price range of α-mercapto-2-thiophene acetic acid in the market?
In "Tiangong Kaiwu", the price range of α-differential-2-butanoic acid in the market varies according to quality and quantity. Usually, those with high quality and abundant quantity have a slightly higher price; those with average quality and small quantity have a slightly lower price.
This acid is useful in all industries, such as medicine and pharmaceuticals, and chemical industry as materials, so its market demand is quite wide. In the market, its price is about twenty to fifty dollars per catty. However, this is only an approximate number, and the actual price varies with the market. If there are many seekers, but there are few suppliers, the price will rise; on the contrary, if the supply exceeds the demand, the price will fall.
And its price is also affected by the location and season. The origin is close to the city, and the production time is suitable, the transportation cost is saved, and the price may be slightly lower; if the origin is far away, the transshipment is difficult, and the season is unfavorable, resulting in a reduction in production, the price will be high.
The price range of α-differential-2-butanoic acid in the city is roughly 20 to 50 dollars per catty, but the actual price often changes due to quality, quantity, market demand, origin, and season. Buyers should carefully observe the market conditions to get a good price.