Z 2 2 Aminothiazol 4 Yl 2 Trityloxyiminothioacetic Acid Benzothiazole Ester
quinoline thiophene imidazole thiazole

(Z)-2-(2-Aminothiazol-4-yl)-2-trityloxyiminothioacetic acid benzothiazole ester

Taiy Chemical

Specifications

HS Code

422170

Chemical Formula C35H27N5O2S3
Molecular Weight 657.82 g/mol
Appearance Solid (usually)
Melting Point Data needed
Boiling Point Data needed
Solubility In Water Low (expected)
Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane (expected)
Pka Data needed
Logp Data needed
Stability Stable under normal conditions (expected), but may react with strong oxidizing or reducing agents
Flash Point Data needed
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General Information
Frequently Asked Questions
What is the main use of (Z) 2- (2-aminothiazole-4-yl) -2-triphenylmethoxy iminothioacetate benzothiazole ester
The main use of (Z) - 2 - (2 - hydroxypyridine - 4 - yl) - 2 - triphenylacetoxy aminoacetyl chromanand pyridinone derivatives lies in their unique effectiveness in many fields such as medicine and chemical industry.
In the field of medicine, such compounds often exhibit excellent biological activity due to their specific chemical structures. For example, some of these derivatives have significant affinity and regulatory effects on biological targets related to specific diseases. In the field of anti-tumor research, they may provide new potential drug options for tumor treatment by inhibiting tumor cell proliferation and inducing tumor cell apoptosis through multiple mechanisms. At the same time, in the field of nervous system diseases, it may play a positive role in neurotransmitter metabolism and nerve cell protection, and it is expected to develop innovative drugs for the treatment of difficult nervous system diseases such as Alzheimer's disease and Parkinson's disease.
In the chemical industry, because of its stable structure and certain reactivity, it can be used as a key intermediate for the synthesis of more complex and excellent organic materials. For example, in the synthesis of polymer materials, the introduction of this derivative structure may endow the material with unique optical and electrical properties, thereby expanding its application in the field of optoelectronics, such as the manufacture of new Light Emitting Diode materials, organic solar cell materials, etc., to promote the development of chemical materials towards high performance and multi-functionality.
In this way, (Z) - 2 - (2 - hydroxypyridine - 4 - yl) - 2 - triphenylacetoxyaminoacetyl chromazopyridone derivatives have broad application prospects in the fields of medicine and chemical industry. Continuous research and development may lead to more potential uses.
What are the synthesis methods of (Z) 2- (2-aminothiazole-4-yl) -2-triphenylmethoxy iminothioacetate benzothiazole ester
The method for the synthesis of (Z) - 2 - (2 - hydroxyquinoline - 4 - yl) - 2 - triphenylacetoxyaminoacetyltianiline derivatives requires various ingenious methods.
To achieve this synthesis, one can borrow the technique of nucleophilic substitution. Select a suitable nucleophilic reagent to interact with the substrate containing the active leaving group. For example, when the nucleophilic hydroxyquinoline-4-yl derivative meets the triphenylacetoxy acetyl halide carrying the leaving group such as halogen atom or sulfonate group, in the presence of appropriate solvent and base, the nucleophilic test agent attacks the leaving group. After substitution reaction, it gradually forms a target bond to form (Z) -2- (2-hydroxyquinoline-4-yl) -2-triphenylacetoxyaminoacetyltianidine derivatives.
Second, the way of condensation reaction. Polymerize with carboxyl group or its active derivative with an amino-containing compound. If 2 - (2 - hydroxyquinoline - 4 - yl) ethylamine meets the acid chloride or acid anhydride of triphenylacetoxyacetic acid, under suitable reaction conditions, the amino group and the carboxyl-derived active group condensate, eliminating small molecules, then the molecular structure is extended, and the desired derivative is finally formed.
In addition, the catalytic addition method can also be selected. Under the help of a specific catalyst, the unsaturated bond can receive a suitable addition reagent. For example, (Z) -2-enyl-2- (2-hydroxyquinoline-4-yl) derivatives containing carbon-carbon unsaturated bonds are added to triphenylacetoxylamine reagents under the action of metal catalysts or other high-efficiency catalysts, and the required groups are precisely introduced to achieve the purpose of synthesizing the target compound.
These various synthesis methods have their own strengths and limitations. They need to be carefully selected and carefully handled according to actual conditions, such as the availability of raw materials, reaction conditions, yield, and purity of the product.
What are the physicochemical properties of (Z) 2- (2-aminothiazole-4-yl) -2-triphenylmethoxy-iminothioacetate benzothiazole ester
(Z) - 2 - (2 - hydroxyquinoline - 4 - yl) - 2 - triphenylacetoxyaminoformyl acetate benzoquinoline ester. The physical and chemical properties of this compound are as follows:
Appearance properties are often white to light yellow crystalline powder, which is easy to identify and operate. Its melting point is determined by intermolecular forces and lattice structure in a specific temperature range, which is of great significance for its purification and identification.
In terms of solubility, it has good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide. Because the molecular structure matches the polarity of the organic solvent, it can form a stable intermolecular interaction. Poor solubility in water, due to the large proportion of molecular hydrophobic parts, it interacts weakly with water.
In terms of stability, it is stable under normal storage conditions. However, in case of strong oxidants, strong acids or strong bases, the structure is easily damaged and decomposed. This is because the functional groups contained in the compound such as ester groups and amino groups are sensitive to acid-base and oxidation. In high temperature or high humidity environments, stability is also affected, or reactions such as hydrolysis and oxidation occur.
The spectral properties are unique. There are characteristic absorption peaks at specific wavenumbers in the infrared spectrum, which correspond to different chemical bond vibrations, such as carbonyl stretching vibrations, which can be used for structure confirmation. Nuclear magnetic resonance spectroscopy can reveal the information of hydrogen atoms or carbon atoms in different chemical environments in molecules, which helps to determine the atomic connection mode and spatial configuration.
These physicochemical properties are of great significance for its synthesis, separation and purification, quality control and application. During synthesis, the reaction conditions and solvents need to be selected according to solubility and stability; the quality control uses the spectral properties to determine the structure and purity; the application field and dosage form should be selected according to the physicochemical properties.
What is the market price of (Z) 2- (2-aminothiazole-4-yl) -2-triphenylmethoxy iminothioacetate benzothiazole ester?
I think what you are asking is about the price of (Z) - 2 - (2 - hydroxyquinoline - 4 - yl) - 2 - triphenoxymethoxyaminoformyloxy benzoic acid quinoline and quinoline hydrazone in the market. The price of these things in the market often varies for many reasons.
First, the difficulty of its preparation has a great impact. If you need to prepare complicated methods and rare raw materials, the price must be high. For example, the ancient method of alchemy, seeking an elixir, needs to collect the world's rare, time-consuming and laborious, and its price is unusual and comparable. To prepare this compound, if the raw materials are rare and the process is complicated, such as finding pearls of the deep sea and medicine of the cliff, the price should also be high.
Second, the supply and demand relationship in the market is the key. If there are many users, they are thirsty for it, but the output is limited, such as water in a drought, the price will rise. On the contrary, if the demand is small, the supply exceeds the demand, such as water after a rain, the price will decline.
Third, the quality of the quality also affects the price. Those with high quality, such as flawless jade, have excellent results and the price is higher than usual.
However, I have not personally touched the market, so it is difficult to determine its specific price. If you want to know the details, you can consult the chemical market, pharmaceutical firms, or ask the merchants and experts who know the market of this product. They will be able to tell you a more accurate price if they have been there for a long time.
What are the Quality Standards for (Z) 2- (2-aminothiazole-4-yl) -2-triphenylmethoxy-iminothioacetate benzothiazole ester
The Quality Standard of (Z) - 2 - (2 - hydroxyquinoline - 4 - yl) - 2 - triphenylacetoxyaminoacetylteaniline ether is the key to many fields such as pharmaceuticals. "Tiangong Kaiwu" does not directly describe this thing, but it can be used for reference in the description of process standards.
View of the ancient craftsmanship, all pay attention to standards and norms. For example, when casting swords, there are rules from the selection of iron, the heat to the number of forging and beating, so that a good edge can be obtained. For pharmaceuticals, the Quality Standard of this compound also needs to be rigorous and thorough.
One is about purity. If impurities exist, or affect the efficacy of the drug, and even have toxic and side effects. It is necessary to use delicate methods, such as extraction, chromatography, etc., to ensure its purity, and the purity should reach a very high standard, almost pure state, before it can be used for medicinal purposes.
Second, the structure is confirmed. By means of infrared, nuclear magnetism and other means, the molecular structure is studied in detail, so that it is compatible with (Z) - 2 - (2 - hydroxyquinoline - 4 - yl) - 2 - triphenylacetoxyaminoacetyltenaniline ether.
Third, stability considerations. Under different conditions of temperature, humidity, light, etc., observe the change of its properties and structure. It should have good stability and not change qualitatively due to the ease of the environment, so as to ensure the constant efficacy of the drug.
Fourth, the inspection of relevant substances. The raw materials, intermediates and degradation products that may remain in the synthesis process need to be carefully tested, and the limit should be strictly set to prevent the accumulation of harmful impurities.
The establishment of the Quality Standard of this compound should be based on science, rigorous, and analogous to the ancient process. Only then can it become a good product available in the pharmaceutical industry.