What are the main uses of Sulfathiazole?

Sulfathiazole is a kind of sulfonamide drug. Its main uses are probably as follows:

First, it is used to treat infections. This drug can control the growth and reproduction of bacteria, and is effective in infections caused by many bacteria, such as pneumococcus, haemolytic streptococcus, etc. It can treat pneumonia, meningitis, carbuncle, otitis media and other diseases. Gai because it can inhibit bacteria from using p-aminobenzoic acid to synthesize dihydrofolic acid, resulting in blockage of bacterial nucleic acid synthesis, and achieve the purpose of bacteriostatic.

Second, it is also useful in trauma treatment. If there is a risk of infection in trauma, thiazole powder can be applied to the wound to prevent bacterial growth and promote wound healing. In the early stage of preventing wound infection, it is quite effective and helps the body resist the invasion of external evils.

Third, it also has certain power in intestinal infections. It can deal with intestinal inflammation caused by Escherichia coli, relieve diarrhea, abdominal pain and other diseases, adjust the flora ecology in the intestines, and restore the normal transportation and transformation of the intestines.

This drug was widely used in the past, but with the development of medicine, although new antibacterial drugs are gradually emerging, thiazole still has certain medicinal value in specific scenarios, making it one of the medicines of choice for doctors to treat diseases.

What are the side effects of Sulfathiazole?

Although sulfathiazole is a good medicine, it also has various side effects, which cannot be ignored.

One of its side effects may cause allergies. The allergic reaction caused by this drug can be seen in the light of rash and itching, the skin is red, the itching is intolerable, and it disturbs people's peace. In severe cases, it can occur as exfoliative dermatitis, with a large area of skin peeling off, which is very scary and endangers life.

Both also affect the blood system. Or cause leukopenia, the body's ability to resist external evil will be weak, prone to various diseases, cold and heat, and fatigue. It may also cause thrombocytopenia, impaired coagulation, and a slight bump, which is prone to petechiae and petechiae, and even can cause visceral bleeding, which is dangerous.

All three, the harm to the kidneys should not be underestimated. Sulfamethiazole and its metabolites have a high concentration in the urine, which is easy to precipitate crystals in the renal tubules, block the urinary tract, cause difficulty in urination, astringent and painful urination, and even cause kidney failure, endangering the foundation of the kidneys, and dysfunction of the viscera.

Furthermore, it also has side effects on the digestive system. Common nausea and vomiting, stomach discomfort, and difficulty in eating. It can also cause diarrhea, abnormal intestinal transportation and transformation, difficulty in retaining nutrients, and loss of body shape.

In addition, long-term or large-scale use may also affect the nervous system, causing headaches, dizziness, fatigue, listlessness, and trance, affecting daily work and life.

When taking medication, carefully observe its side effects, weigh the pros and cons, and use it with caution to maintain health.

Sulfathiazole usage and dosage

Sulfathiazole is a drug. The method and amount of its use vary according to the disease in the past.

If it is used for the treatment of general inflammation, it is often necessary to take it internally. The initial dosage for adults is usually one to two grams at a time, and then 0.5 to one gram every four to six hours. The dosage for children is determined according to their weight. About 0.05 to 0.1 grams per kilogram of body weight per day is used, and it is also taken several times.

If used externally, it is often made into a paste or powder. For skin sores and ulcers, thiothiazole powder can be applied to the affected area, or applied with a paste to help it reduce inflammation and remove swelling. Change the medicine a day or several times, depending on the shape of the sores.

When taking medicine, be cautious. Doctors should carefully observe the patient's physical condition and the severity of the disease to determine the appropriate usage and dosage. During the medication, if you see any discomfort, such as rash, abdominal pain, etc., you should stop the medication immediately and treat it properly. This is the approximation of the previous usage and dosage of thiothiazole. The appropriate medication still needs to follow the doctor's advice.

What are the storage conditions for Sulfathiazole?

Sulfathiazole is a drug, and its storage conditions are quite important, which is related to the efficacy and quality of the drug.

This drug should be stored in a dry place. Cover moisture can easily cause deliquescence of the drug, causing its chemical composition to change and its efficacy to be damaged. If it is in a humid place, thiothiazole may absorb water, causing its properties to change, such as agglomeration, which in turn affects its disintegration and absorption in the body.

And should be placed in a cool place to avoid high temperature. High temperature can accelerate the chemical reaction of the drug, causing it to decompose and deteriorate. If the temperature is too high, the molecular structure of thiothiazole may be damaged, the efficacy of the drug will be reduced, and even harmful impurities will be produced.

Furthermore, it needs to be stored in a dark place. Light, especially ultraviolet light, has energy and can lead to photochemical reactions of drugs. Thiothiazole is exposed to light, or causes structural changes, which affect the curative effect.

In addition, make sure that the container is well sealed when storing. This can prevent outside air, moisture and microbial intrusion. If the container is not sealed, oxygen in the air may cause drug oxidation, and the growth of microorganisms will contaminate the drug, which is not good for the quality of the drug.

In short, in order to preserve the efficacy and quality of thiothiazole, it must be stored in strict accordance with dry, cool, shaded and sealed storage conditions.

How does Sulfathiazole interact with other medications?

Sulfathiazole is also an antibacterial drug of sulfadiazole. The interaction between it and other drugs cannot be ignored.

Combined with the antibacterial synergist trimethoprim, the synergistic use of the two can greatly increase the antibacterial activity, because the two act on different links of bacterial folic acid metabolism, complement each other, and the stronger the antibacterial and bactericidal power.

In case of basic drugs, such as sodium bicarbonate, the solubility or change of sulfathiazole reduces the risk of crystallization in urine, which can prevent the formation of urinary tract stones. However, it is also necessary to pay attention to its effect on drug absorption and excretion. < Br >
When taken with oral anticoagulants, the plasma protein binding rate of anticoagulants may decrease, the concentration of free drugs will increase, the anticoagulation effect will be hyperactive, and the risk of bleeding will increase sharply. It is necessary to carefully check the coagulation index when using the drug.

If used in combination with hypoglycemic drugs, or to enhance the efficacy of hypoglycemic drugs, there is a risk of hypoglycemia. Therefore, the user should frequently measure blood sugar to prevent blood sugar from falling.

In combination with methotrexate, it may affect the metabolism and excretion of methotrexate, resulting in the accumulation of toxicity. It should be used with caution and close monitoring of adverse reactions is required.

All medicines are used in combination, and the advantages and disadvantages are accompanied. When the doctor uses the medicine, he must carefully review the condition and weigh the advantages and disadvantages to ensure that the patient's medication is safe and effective.