Succinylsulfathiazole

Sulfothiazole (Succinylsulfathiazole) is a drug. This drug is a sulfonamide antimicrobial agent, which was widely used in the past. It is derived from sulfothiazole and added with succinyl groups to increase its solubility and absorbability.
Its mechanism of action is to inhibit the synthesis of folic acid in bacteria to achieve antibacterial effect. Bacteria rely on folic acid to synthesize nucleic acids and proteins. This drug can block dihydrosphenoic acid synthase, causing bacteria to fail to synthesize folic acid, and growth and reproduction are inhibited.
In clinical practice, it was often used to treat intestinal infections, such as bacterial dysentery and enteritis. After oral administration, part of it is absorbed in the intestines, and the rest remains in the intestines, which can inhibit intestinal pathogenic bacteria.
However, due to the development of antibiotics and drug resistance, its application is decreasing. Many new antibacterial drugs have better efficacy and safety. However, under specific circumstances or due to special needs, it is still occasionally used.
In summary, sulfamethiazole was an important intestinal antibacterial drug in the past, and it has a certain position in the development of medicine. Although it is not as widely used as in the past, its historical role cannot be ignored.

Amber sulfamethiazole is an antibacterial drug of sulfonamides. Its main use is quite wide.
First, it has a significant effect on the treatment of intestinal infections. Such as bacillary dysentery, this disease is caused by diarrheal bacillus, causing intestinal damage, and the patient has frequent abdominal pain, diarrhea, and severe tenderness. Amber sulfamethiazole can enter the intestines, inhibit the growth and reproduction of diarrheal bacillus, weaken the bacterial potential, slow down intestinal inflammation, and relieve various diseases, helping patients recover.
Second, it is also commonly used for the treatment of enteritis. The causes of enteritis are various, or due to unclean diet, or due to intestinal flora disorders. Amber sulfamethiazole can inhibit harmful bacteria in the intestines, regulate the balance of flora, relieve inflammation of intestinal mucosa, and promote intestinal function to return to normal, diarrhea and abdominal pain gradually disappear.
Third, it is also important in preventing infection after abdominal surgery. During abdominal surgery, the intestines are easily affected, and bacteria are easy to breed and cause infection. Reasonable use of amber sulfamethiazole before or after surgery can reduce the number of intestinal bacteria, block the way of infection, ensure smooth healing of surgical wounds, prevent complications of infection, and help patients recover smoothly after surgery.

Amber sulfamethiazole (Succinylsulfathiazole), although used as an antibacterial agent in the past, there are many side effects.
Its side effects are first and foremost in the gastrointestinal tract. Often cause nausea and vomiting, this is because the drug stimulates the gastrointestinal mucosa and disturbs its normal transportation and transformation. The spleen and stomach are affected by evil, the elevation and descent of the digestion, and the stomach qi is reversed, resulting in nausea and vomiting. And easy to cause diarrhea, because the drug affects the balance of the normal intestinal flora, the qi does not rise, the turbid gas does not fall, the water and grain essence cannot be transported and absorbed normally, and the large intestine is injected, resulting in diarrhea.
Furthermore, it also affects the hematopoietic system. It can cause leukopenia, which is because the drug inhibits the hematopoietic function of the bone marrow and makes the White blood cells, the body's guard against external evil, reduce the number, the body's external function weakened, susceptible to exogenous diseases. In severe cases, or cause thrombocytopenia, platelets are responsible for coagulation, and the number is insufficient, the coagulation function is dysfunctional, and purpura, hemorrhage and other diseases can occur.
And allergic reactions. Or see rash, this is the evil of drug poison invading the skin, and it is contained in the skin, and it is a rash. It may even cause exfoliative dermatitis, large exfoliation of the skin, and the condition is critical. There are also those who cause drug fever, drug evil enters the body, good and evil fight, and the camp and guard are dysregulated, causing fever.
In addition, it is also unfavorable to the urinary system. It can precipitate crystals in urine and block the urinary tract. This is due to the decrease in solubility of drug metabolites in urine and the deposition of crystals. If the urinary tract is blocked, it will be unfavorable for urination, and it can cause low back pain, hematuria, etc.
From this perspective, although amber sulfamethiazole once had antibacterial effects, its side effects are numerous and may cause serious consequences, and it is rarely used today. When taking medication, the pros and cons should be carefully weighed to ensure the well-being of the patient.

Amber sulfamethiazole (Succinylsulfathiazole) is also a sulfonamide drug. It is suitable for diseases with intestinal infections, such as bacillary dysentery, enteritis, etc.
The applicable population is mostly people with intestinal diseases. If people are affected by dysentery bacteria, Escherichia coli, etc., causing intestinal dysfunction, abdominal pain, diarrhea, diarrhea, sepsis, etc., this drug can be used.
However, if children suffer from intestinal infections, because of their delicate organs, the medication should be careful, and the dosage should be determined according to their weight and condition. The elderly's organs are gradually failing, and if the intestines are infected and the constitution is weak, it can also be used, but the physical reaction should be paid attention to during the medication process, because its tolerance may be different.
In addition, people who usually have spleen and stomach deficiency and cold should also be cautious when using this medicine. Because it may injure the spleen and stomach, the spleen and stomach need to be taken care of during medication. If there is any discomfort after taking the medicine, such as epigastric pain, nausea and vomiting, etc., seek medical attention in time. In short, this medicine is suitable for people with intestinal infections, but different groups of people have their own taboos when using it. Only when used with syndrome differentiation can we do our best to avoid its harm.

Succinylsulfathiazole, that is, succinylsulfamethylthiazole. This is a drug. If you want to use it properly, you need to understand its pharmacology and usage.
The way of medication should first follow the doctor's advice. Doctors determine the amount of medication according to the patient's symptoms, physical strength, age and other conditions. If a young child is not fully charged, the amount of medication should be less than that of an adult to prevent drug harm.
When taking medication, it should be taken on time. Or before or after meals, each has its own reasons. If fasting is prone to gastrointestinal discomfort, it is better to use it after meals to reduce gastrointestinal injuries. And when taking this medicine, it should be sent with warm water to help it dissolve quickly and facilitate its absorption.
During the medication period, it is also necessary to pay attention to changes in the body. Observe whether there are any adverse reactions, such as rash, pruritus, gastrointestinal pain, ejaculation, etc. If there is any abnormality, tell the doctor immediately, and the doctor can adjust the medicine or stop it.
Also, during the medication period, you should also pay attention to your diet. Avoid spicy and greasy things to prevent them from being confused with the medicine and reduce its efficacy.
Furthermore, the storage of this medicine should also be obtained. It should be placed in a dry and cool place, protected from heat and moisture, to prevent its deterioration. In this way, the purpose of medication can be achieved, and the disease can be cured and the body can be kept healthy.