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What is the chemical structure of S-2-Benzothiazolyl-2-Amino- alpha (methoxyimino) -4-Thiazolethiolacetate?
This is an organic compound, and its name is S-2-benzothiazolyl-2-amino - α -( methoxyimino) -4-thiazole thioacetate. To clarify its chemical structure, consider its name.
"2-benzothiazolyl" means that there is a group of benzothiazole in the molecule. Benzothiazole is formed by fusing a benzene ring with a thiazole ring and has a specific heterocyclic structure. "2-amino" means that there is an amino-NH -2 at a specific position. " Alpha - (methoxy imino) ", which means that there is a structural fragment connected by methoxy-OCH
and imino = NH, and this fragment is connected to a specific α position." 4-thiazole ", indicating that there is another thiazole ring, and the substituent is connected to the 4th position of the thiazole ring." Thioacetate ", indicating the existence of an acetate structure, in which the oxygen atom is replaced by a sulfur atom, that is, the -S-CO-CH
The chemical structure of this compound can be obtained by combining the structural fragments according to the naming rules. Its structure contains heterocycles such as benzothiazole and thiazole, as well as amino, methoxyimino, thioacetate and other functional groups. Each part is interconnected to form a unique chemical structure, which makes it have specific chemical properties and reactivity.
What are the main uses of S-2-Benzothiazolyl-2-Amino- alpha - (methoxyimino) -4-Thiazolethiolacetate?
S - 2 - benzothiazolyl - 2 - amino - α -( methoxyimino) - 4 - thiazole thioacetate, which has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many antibacterial drugs. Due to its special chemical structure, it can construct a core structure of antibacterial active molecules through specific reaction steps, which helps to synthesize high-efficiency antibacterial drugs and provides a powerful weapon for resisting bacterial infections and diseases.
It also plays an important role in the manufacture of pesticides. It can be used as a raw material to participate in the synthesis of some high-efficiency and low-toxicity pesticides. With its unique chemical properties, the synthesized pesticides have high targeted lethality to pests, are environmentally friendly, degrade quickly, have little residue, effectively protect the growth of crops, and reduce the negative impact on the ecological environment.
In the field of fine chemicals, it is used as a special organic synthesis raw material for the preparation of fine chemicals with unique functions. For example, in the synthesis of some special coatings and additives, specific properties can be given to the products, such as improving the adhesion of coatings and enhancing the stability of additives, so as to expand the application range of fine chemical products and meet the diverse needs of different industrial fields for material properties.
What is the preparation method of S-2-Benzothiazolyl-2-Amino- alpha - (methoxyimino) -4-Thiazolethiolacetate?
To prepare S - 2 - benzothiazolyl - 2 - amino - α - ( methoxyimino) - 4 - thiazole thioacetate, the method is as follows:
First take an appropriate amount of 2 - amino - 4 - thiazole thioacetic acid as the starting material and place it in a clean reactor. Dissolve it in a suitable organic solvent, such as dichloromethane or N, N - dimethylformamide, which needs to be dried to remove the moisture and prevent it from disturbing the reaction.
Then, the reagent containing methoxyimino is slowly added to the reaction system. The preparation of this methoxy imino-containing reagent needs to be fine to ensure its purity. When adding, the temperature should be controlled in a suitable range, usually low temperature, such as between 0 ° C and 5 ° C, and it needs to be slowly added dropwise under stirring to make the reaction proceed uniformly and prevent local overheating or overreaction.
At the same time, take 2-benzothiazolyl reagent and add it after the above reaction system reaches a certain degree of reaction in an appropriate proportion. After adding, gradually raise the temperature to a moderate temperature, such as 30 ° C to 50 ° C, and continue to stir to make the reaction sufficient. During this process, the reaction process should be monitored by thin-layer chromatography or other suitable analytical methods, and the consumption of reactants and the formation of products should be monitored from time to time. < Br >
After the reaction is completed, pour the reaction solution into an appropriate amount of separation device. Extract with a suitable extractant, such as a mixed system of ethyl acetate and water, and extract multiple times to extract the target product. After extraction, combine the organic phases and dry them with a desiccant such as anhydrous sodium sulfate to remove the moisture.
Then, the organic solvent is distilled under reduced pressure to obtain a crude product. The crude product is then refined by recrystallization. Select a suitable recrystallization solvent, such as a mixed solvent of ethanol and water, heat to dissolve the crude product, filter while hot, cool the crystallization, and filter to obtain the refined product, that is, S-2-benzothiazolyl-2-amino - α - ( methoxy imino) - 4 -thiazole thioacetate. The whole process requires fine operation, temperature control, time control and material ratio are all key to obtain high-quality products.
S-2-Benzothiazolyl-2-Amino- is the safety of alpha (methoxyimino) -4-Thiazolethiolacetate?
Guanfu S - 2 - benzothiazolyl - 2 - amino - α - ( methoxy imino) - 4 - thiazole thiol acetate, the safety of this product, the study is related to many.
For chemical properties, this compound has a specific molecular structure, benzothiazolyl, thiazolyl and other structures give it unique chemical activity. However, such structures or under specific conditions, react with other substances, producing unknown by-products, which affects its safety. Such as in the environment of high temperature, strong acid and alkali, or cause decomposition, polymerization and other reactions, resulting in harmful substances.
In terms of toxicity, although the specific toxicity data are not detailed, the heterocyclic structure containing sulfur and nitrogen may have certain biological toxicity. Or enter the body through respiratory tract, skin contact, accidental ingestion, etc., affecting the physiological function of the human body. Or damage the liver, kidneys and other organs, or interfere with the normal operation of the nervous system.
In terms of environmental impact, if it is accidentally released in the environment, in water, soil, or due to its own chemical stability, it persists in the ecosystem. Or affect the growth and reproduction of microorganisms, disrupt the ecological balance of the soil; in water bodies, or affect the survival of aquatic organisms, such as fish, algae, etc., and then affect the entire aquatic ecological chain.
Review its production, storage and transportation. During production, raw materials and intermediate products may be dangerous, such as improper operation, or leakage, explosion and other accidents. Storage requires specific conditions. If the temperature and humidity are not well controlled, or deterioration is caused. During transportation, if the packaging is damaged, there are also risks, endangering the transportation personnel and the surrounding environment. The safety of S - 2 - benzothiazolyl - 2 - amino - α - ( methoxyimino) - 4 - thiazole thiol acetate requires rigorous testing and evaluation, taking into account the chemical characteristics, toxicity, environmental impact and operation of each link.
S-2-Benzothiazolyl-2-Amino- alpha - (methoxyimino) -4-Thiazolethiolacetate market prospects?
S - 2 - benzothiazolyl - 2 - amino - α -( methoxyimino) - 4 - thiazole thioacetate, which is related to the pharmaceutical and chemical industry in the pharmaceutical market.
Looking at the field of pharmaceutical and chemical industry today, the demand for antibacterial drugs is constant. This compound is a key pharmaceutical intermediate and plays an indispensable role in the synthesis of new antibacterial drugs, especially cephalosporins. Its market prospects are converging bit by bit, and the future is quite bright.
From a global perspective, the market size of antibacterial drugs continues to expand. Due to the growth of the population, the aging of the population, and the frequent occurrence of various infectious diseases, the demand for antimicrobials continues to increase. S-2-benzothiazolyl-2-amino - α -( methoxyimino) - 4-thiazole thioacetate is an important intermediate, and its market has also expanded.
Furthermore, science and technology are new, and pharmaceutical research and development is advancing rapidly. The research and development of new cephalosporins is in the ascendant, and the quality and quantity of this intermediate are higher. Therefore, it has become an industry priority to study the production process and improve product quality. In this way, those who master advanced processes can gain an advantage in the market and gain more business opportunities.
However, the road to the market is not a smooth one. Environmental regulations are becoming stricter, and enterprises that produce this intermediate must comply and increase environmental protection investment. And the competition in the same industry is fierce. All enterprises are seeking to reduce costs and increase efficiency, introduce new ones, and win the market.
In general, S-2-benzothiazolyl-2-amino - α -( methoxyimino) - 4-thiazole thioacetate The market prospect is broad, and opportunities and challenges coexist. Enterprises that seize opportunities and face challenges bravely will be able to sail at the forefront of the market.