What is the chemical structure of (S) -2-Amino-4,5,6,7-tetrahydro-6- (propylamino) benzothiazole dihydrochloride monohydrate?

(S) -2-amino-4,5,6,7-tetrahydro-6- (alanine) benzothiazole dihydrochloride monohydrate, which is an organic compound. Its chemical structure is quite complex, let me describe it in detail.

Benzothiazole is the core parent nucleus of this compound, which is formed by fusing the benzene ring with the thiazole ring. The thiazole ring is a five-membered heterocycle containing a sulfur atom and a nitrogen atom, and the benzene ring is fused with it, giving this compound unique stability and chemical activity. < Br >
In the 2-position of the parent nucleus of benzothiazole, there is an amino group connected, and the existence of the amino group makes this compound basic and can form salts with acids, which is also the reason for the subsequent formation of dihydrochloride salts.

In the 4,5,6,7-position, it has a tetrahydro structure, which is the result of the partial hydrogenation of the parent nucleus of benzothiazole. The introduction of the tetrahydro structure changes the spatial configuration and electron cloud distribution of the molecule, affecting its physical and chemical properties.

is particularly critical, the 6-position is connected with an alanyl group, and the propyl group is an alkyl group, which has certain hydrophobicity. The presence of an alanyl group further enriches the chemical properties and spatial structure of the compound, and may have an important impact on its biological activity.

As for dihydrochloride, due to the alkalinity of the amino group, it can react with hydrochloric acid to form salts, which enhances the water solubility of the compound. And monohydrate, indicating that the crystallization process of the compound contains a molecule of crystal water in the lattice, and the existence of crystal water will also affect the stability and physical properties of the compound, such as melting point and solubility.

In summary, the chemical structure of (S) -2-amino-4,5,6,7-tetrahydro-6- (alanyl) benzothiazole dihydrochloride monohydrate is composed of benzothiazole mother nucleus, amino group, tetrahydro structure, alanyl group, dihydrochloride and crystalline water. Each part interacts to endow this compound with unique chemical and physical properties.

What are the physical properties of (S) -2-Amino-4,5,6,7-tetrahydro-6- (propylamino) benzothiazole dihydrochloride monohydrate?

(S) -2-amino-4,5,6,7-tetrahydro-6- (alanyl) benzothiazole dihydrochloride monohydrate, this is an organic compound with unique physical properties. It is in the state of white to off-white crystalline powder at room temperature and pressure, which is easy to observe and process.

From the perspective of its solubility, it should have good solubility in water. Due to the molecular structure containing polar groups, it interacts with water molecules to make the compound easily soluble in water and form a uniform solution. This property is crucial in many chemical and biological experimental applications, because aqueous solutions are often the medium for reaction or analysis.

Discuss the melting point, the compound may have a specific melting point range. Melting point is an important physical constant of a substance, which can help identify and determine purity. When heated to the melting point of this compound, it gradually melts from a solid state to a liquid state. This process requires precise temperature control and observation.

In addition, the compound may have a certain degree of hygroscopicity. Because some groups in its structure have an affinity for water molecules, in a high humidity environment, it is easy to absorb moisture in the air, or cause its morphology and quality to change. Pay attention when storing and using it. It should be properly sealed to prevent it from affecting the quality and performance due to moisture absorption.

As for its density, although the exact value needs to be determined experimentally, it can be inferred from its molecular structure and the properties of similar compounds that there should be a specific density range, which is of great significance for accurate measurement and calculation of its dosage in different systems.

In summary, the physical properties of (S) -2 -amino-4,5,6,7 -tetrahydro-6- (alanyl) benzothiazole dihydrochloride monohydrate, such as morphology, solubility, melting point, hygroscopicity and density, are crucial for in-depth understanding and rational application of this compound.

What is the main use of (S) -2-Amino-4,5,6,7-tetrahydro-6- (propylamino) benzothiazole dihydrochloride monohydrate?

(S) -2-Amino-4,5,6,7-tetrahydro-6- (alanyl) benzothiazole dihydrochloride monohydrate, which is crucial in the field of medicine. In the pharmaceutical field, it is often the key raw material for the creation of new drugs. After in-depth investigation, many researchers have found that it has potential efficacy in the treatment of specific diseases, such as neurological disorders and cardiovascular diseases.

From the perspective of chemical structure, the unique molecular structure of this compound gives it special chemical and biological activities. This structural feature allows it to precisely interact with specific biological targets in the body, or adjust specific physiological processes, so as to exert the effect of treating diseases.

In the process of drug development, chemists and pharmacologists make every effort to study its pharmacological mechanism, pharmacokinetic properties and safety. Through a large number of experimental and clinical studies, it is hoped to clarify its mode of action, metabolic pathway and possible side effects in the human body. This compound may play a therapeutic role in neurological diseases by modifying the release and reuptake of specific neurotransmitters; or by affecting the physiological function of the cardiovascular system, it can achieve the purpose of treating cardiovascular diseases. Therefore, (S) - 2 - amino - 4,5,6,7 - tetrahydro - 6 - (alanyl) benzothiazole dihydrochloride monohydrate has broad prospects in the field of pharmaceutical research and development, and brings new hope for conquering many difficult diseases.

What are the synthesis methods of (S) -2-Amino-4,5,6,7-tetrahydro-6- (propylamino) benzothiazole dihydrochloride monohydrate?

(S) -2 -amino-4,5,6,7 -tetrahydro-6- (alanyl) benzothiazole dihydrochloride monohydrate has various paths to follow.

First, the benzothiazole skeleton can be constructed from the starting material through multi-step reaction. First select a benzene ring derivative containing a suitable substituent and react with a sulfur-containing reagent under suitable conditions to form a benzothiazole parent nucleus. This process requires attention to the choice of reaction temperature, solvent and catalyst to promote the efficient reaction. For example, when a specific halogenated benzene is used as the starting material, in the presence of a base and a phase transfer catalyst, it can be heated and refluxed in an organic solvent with a thioamide reagent to generate a preliminary benzothiazole structure.

Second, after the benzothiazole skeleton is constructed, the 6-position alanine group is introduced. The nucleophilic substitution reaction can be used to react the halogenated propane derivative with the benzothiazole intermediate under the action of a base. The key to this step is to control the strength of the base and the reaction time to avoid overreaction or side reactions.

Third, after the key structure is formed, the amino group is introduced and the salt formation reaction is carried out. 2-Amino group is introduced under suitable conditions by suitable amination reagent. Subsequently, the obtained product is reacted with hydrochloric acid to form a dihydrochloride salt, and then properly treated to obtain a hydrate containing one of the crystal water. Attention should be paid to controlling the pH and crystallization conditions of the reaction system to obtain high-purity products.

Throughout the synthesis process, each step of the reaction needs to be carefully regulated, and attention should be paid to the optimization of the reaction conditions and the purification of the intermediate, in order to effectively and productively obtain (S) -2-amino-4,5,6,7-tetrahydro-6- (alanine) benzothiazole dihydrochloride monohydrate.

(S) -2-Amino-4,5,6,7-tetrahydro-6- (propylamino) benzothiazole dihydrochloride monohydrate What are the precautions during use?

(S) - 2-Amino-4,5,6,7-tetrahydro-6- (alanine) benzothiazole dihydrochloride monohydrate, which is a rather complex chemical substance. During use, many precautions need to be kept in mind.

Bear the brunt of it, and safety protection should not be underestimated. Because it has chemical activity or is harmful to the human body. When operating, wear suitable protective clothing, such as laboratory clothes, gloves, and goggles to fully protect yourself from potential contact and splashes. If it comes into contact with the skin or eyes, rinse with plenty of water immediately and seek medical attention according to the actual situation.

Furthermore, accurate weighing and operation are essential. This substance has special properties, and the dosage is slightly deviated, or the experimental results may be fallacious. Be sure to use accurate weighing tools and operate strictly according to regulations to ensure that the dosage is accurate.

Storage conditions should not be ignored. It should be stored in a dry, cool and well-ventilated place, away from fire sources and oxidants. Because it may be hygroscopic, it should be properly sealed and stored to prevent moisture and deterioration, affecting its chemical properties and use effect.

The use environment should also be carefully considered. It should be operated in a fume hood to ensure that harmful gases are discharged in time to avoid inhalation by experimenters. And the operating table must be kept clean and dry to avoid impurities from mixing in and interfering with the experimental process.

In addition, waste disposal after use should not be sloppy. Relevant environmental regulations must be followed, properly disposed of, and must not be discarded at will to avoid pollution to the environment. Only in this way can the purpose of safe and efficient use be achieved.