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What is the chemical structure of (−) - (S) -2,3,5,6 -tetrahydro-6 -phenylimidazo [2,1 - b] thiazole monohydrochloride
(-) - (S) -2,3,5,6-tetrahydro-6-phenylimidazolo [2,1-b] thiazole monohydrochloride, which is an organic compound. Looking at its name, it can be known that its structure contains specific functional groups and spatial configurations.
First, the parent nucleus of imidazolo [2,1-b] thiazole is formed by fusing the imidazole ring with the thiazole ring. The imidazole ring has two nitrogen atoms, which has certain basic and reactive activity; the thiazole ring contains sulfur and nitrogen atoms, which also have an important impact on the properties of the compound. After fusing the two rings, the parent nucleus structure is more complex and stable. < Br >
At positions 2, 3, 5, and 6, it has a tetrahydrogen structure, indicating that this part is a saturated carbon chain, which is more stable in chemical properties than the unsaturated structure. The 6-position is connected with a phenyl group, and the phenyl group is an aromatic group. It has a conjugated system, which can affect the electron cloud distribution of the compound, make it have a certain aromaticity, and affect the physical and chemical properties, such as solubility, stability and reactivity.
(-) - (S) indicates that it is chiral, which is a left-handed configuration and a specific chiral center is S-type. Chirality has a great impact on the biological activity and pharmacological properties of compounds. Different chiral isomers may have different metabolic pathways and physiological effects in organisms.
Furthermore, it is a monohydrochloride salt, that is, the compound forms a salt with one molecule of hydrogen chloride. After salt formation, the water solubility of the compound usually increases, which is conducive to the preparation and absorption in vivo, and the stability of the salt is also different from that of the parent compound.
In short, the chemical structure of (-) - (S) -2,3,5,6-tetrahydro-6-phenylimidazolo [2,1-b] thiazole monohydrochloride is composed of a specific fused heterocyclic parent nucleus, saturated carbon chain, aromatic substituent, chiral center and salt-forming form. The interaction of each part determines its unique physicochemical and biological activity properties.
What are the physical properties of (−) - (S) -2,3,5,6 -tetrahydro-6 -phenylimidazo [2,1 - b] thiazole monohydrochloride
(−) - (S) -2,3,5,6-tetrahydro-6-phenylimidazolo [2,1-b] thiazole monohydrochloride, which is an organic compound. Its physical properties are quite important and affect many application fields.
Looking at its appearance, it is often in the state of white to quasi-white crystalline powder at room temperature and pressure. This characteristic is the key basis for the identification and preliminary judgment of substances. In terms of solubility, it exhibits certain solubility characteristics in specific organic solvents. For example, it is easily soluble in polar organic solvents such as methanol and ethanol. Due to the interaction of polar groups contained in the molecular structure with the solvent, the dissolution process can occur. In water, it also has a certain solubility, but it is relatively limited. This property affects its dispersion and application in different media.
When it comes to the melting point, it has been accurately determined to be in a certain temperature range. The determination of this temperature range is of great significance for the determination of the purity of the compound and the study of thermal stability. If the melting point deviates from the normal range, it may suggest that the purity of the substance is poor or the crystal structure is different.
In addition, the compound has a certain degree of hygroscopicity. In a high humidity environment, it is easy to absorb moisture in the air, causing changes in its own state, or agglomeration, or deliquescence, which places strict requirements on its storage and transportation conditions. It is necessary to ensure that the environment is dry to prevent deterioration. These physical properties provide an important reference for the preparation, storage, and application of the compound, which cannot be ignored in industrial production and scientific research practice.
What is the use of (−) - (S) -2,3,5,6 - tetrahydro - 6 - phenylimidazo [2,1 - b] thiazole monohydrochloride
(−) - (S) -2,3,5,6-tetrahydro-6-phenylimidazolo [2,1-b] thiazole monohydrochloride, this substance has a wide range of uses. In the field of medicine, it is of great significance in the process of drug development. Many new drugs are created with it as a key intermediate. Through chemical modification and structural modification, it is expected to develop drugs with better efficacy and less side effects. For example, in the development of some anti-parasitic drugs, it can be used as a starting material to synthesize compounds with high anti-parasitic activity through a series of chemical reactions.
In the field of organic synthesis, it is also an important synthetic building block. With its unique molecular structure, it can participate in a variety of organic reactions and build a more complex organic molecular skeleton. Chemists use its reaction characteristics to ingeniously design reaction routes to achieve the synthesis of organic compounds with specific structures and functions, such as in the synthesis of organic materials with special optical properties or biological activities.
In scientific research and exploration, scientists conduct in-depth research on its physical and chemical properties and reaction mechanisms. By accurately determining its melting point, solubility and other physical properties, as well as analyzing its reaction process under different reaction conditions, to deepen the understanding of the chemical behavior of nitrogen-containing and sulfur-containing heterocyclic compounds, and lay a solid foundation for the research and application of subsequent related compounds.
What is the synthesis method of (−) - (S) -2,3,5,6 -tetrahydro-6 -phenylimidazo [2,1 - b] thiazole monohydrochloride
(−) - ( S) - 2,3,5,6 - tetrahydro - 6 - phenylimidazolo [2,1 - b] thiazole monohydrochloride synthesis method, the ancient book "Tiangong Kaiwu", although not contained in the method of synthesis of this substance, but its "exhaustive test" "clever method" is also the standard in today's synthesis of this compound, often follow the path of organic synthesis.
At the beginning, suitable starting materials can be selected, such as nitrogen-containing compounds with specific functional groups, sulfur-containing compounds and aryl halides. Using the nitrogen-containing imidazole ring precursor and the sulfur-containing thiazole ring precursor as the basis, using the reaction mechanism of organic chemistry, the condensation reaction is carried out. In the reaction system, the temperature and pressure are adjusted appropriately, and a catalyst, such as a metal catalyst or an organic base, is used to promote the reaction.
If the classical nucleophilic substitution reaction starts, the halogenated aromatics and the nucleophilic reagents containing nitrogen and sulfur can be gradually constructed under the catalysis of a metal catalyst in an organic solvent. Afterwards, the double bond is hydrogenated to achieve the structure of tetrahydro.
After the parent nucleus is formed, it is treated with hydrochloric acid to form a monohydrochloride salt. This process requires fine control of the reaction conditions, such as the concentration of hydrochloric acid, the reaction time and temperature, to maintain the purity and yield of the product. And after each step of the reaction is completed, it must be separated and purified, such as column chromatography, recrystallization, etc., to remove impurities and obtain pure (−) - ( S) - 2,3,5,6 - tetrahydro - 6 - phenylimidazolo [2,1 - b] thiazole monohydrochloride.
(−) - (S) -2, 3, 5, 6 - tetrahydro - 6 - phenylimidazo [2,1 - b] thiazole monohydrochloride
(−) - (S) -2,3,5,6-tetrahydro-6-phenylimidazolo [2,1-b] thiazole monohydrochloride, which is a promising chemical substance. Looking at its market prospects, the demand for it is gradually rising in many fields today.
In the field of pharmaceutical research and development, due to its unique chemical structure or significant biological activity, it can be used as a lead compound to help create new drugs. As people pay more attention to health, the pharmaceutical market is booming, and the demand for such potential compounds is also rising.
In the field of materials science, its special properties may bring opportunities for the development of novel functional materials. With the advancement of science and technology, the field of materials continues to expand, and the demand for compounds with special structures and properties is increasing. This compound may emerge in it.
However, its market also has challenges. The complexity of the synthesis process or the high production cost, restricting large-scale production and wide application. And the market competition is fierce, with similar or alternative products emerging in an endless stream. To gain a place in the market, it is necessary to optimize the synthesis process, reduce costs, and enhance product competitiveness.
Overall, (−) - (S) -2,3,5,6-tetrahydro-6-phenylimidazolo [2,1-b] thiazole monohydrochloride faces challenges, but with its unique properties, it has broad prospects in the fields of medicine, materials, etc. With time and appropriate strategies, it will surely shine.