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What is the chemical structure of -2-amino-6-propionamido-4, 5, 6, 7-tetrahydrobenzothiazole?
(R) -2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole has a unique chemical structure. This compound contains the parent nucleus of benzothiazole, which is fused from a benzene ring and a thiazole ring. The benzene ring is a six-membered aromatic ring with a conjugated electronic system, which gives it stability. The thiazole ring is a five-membered heterocycle containing sulfur and nitrogen atoms. The two are arranged in a specific space in the ring, which has a significant impact on the properties of the compound.
In the second position of the benzothiazole nucleus, there is an amino group connected, and the amino group is basic. It can participate in many chemical reactions, such as salting with acids or reacting with electrophilic reagents. The 6-position is connected with a propionamide group, the amide group is -CONH-structure, and the propyl group is attached to the carbonyl carbon. The amide group has certain stability, but under certain conditions, reactions such as hydrolysis can also occur.
In addition, the 4,5,6,7-position is in the state of tetrahydro, that is, part of the double bond of the benzothiazole nucleus is reduced to a single bond, resulting in a decrease in the degree of unsaturation of the molecule and a change in the spatial structure, which affects its physical and chemical properties. The various characteristics and interactions of this chemical structure make the compound have unique uses and potential activities in the fields of organic synthesis, medicinal chemistry, etc.
(R) What are the physical properties of -2-amino-6-propionamido-4, 5, 6, 7-tetrahydrobenzothiazole?
(R) -2-Amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole is also an organic compound. Its physical properties are worth exploring.
Looking at its morphology, under normal conditions, it is mostly white to white solid powder, which is easy to store and use, and the powder texture is fine, reflecting its microstructure characteristics.
The melting point is about a specific temperature range. This temperature marks the critical state of the compound from solid to liquid. The exact value of the melting point is crucial for its identification and purity determination.
In terms of solubility, it has a certain solubility in common organic solvents. In some polar organic solvents, such as ethanol, dimethyl sulfoxide, etc., it can show good solubility and can form a uniform solution system; however, in non-polar organic solvents, such as n-hexane, benzene, etc., the solubility is poor. This solubility characteristic is closely related to the polarity and functional group structure of the compound molecule. The molecule contains both polar groups such as amino groups and amide groups, as well as relatively non-polar parts such as benzothiazole rings, so it has different solubility behaviors in different solvents.
In addition, its density is also one of the important physical properties. Under specific conditions, the compound has a certain density value, which reflects its mass per unit volume, and has significant significance for its application in chemical production, preparation and many other fields.
In summary, the morphology, melting point, solubility and density of (R) -2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole together outline its unique physical and chemical profile, laying the foundation for its further research and application.
(R) What are the synthesis methods of -2-amino-6-propionamido-4, 5, 6, 7-tetrahydrobenzothiazole?
The synthesis of (R) -2-amino-6-propionylamino-4,5,6,7-tetrahydrobenzothiazole is an important topic in the field of organic synthesis. The synthesis of this compound can follow several paths.
First, it can be started from suitable sulfur-containing and nitrogen-containing starting materials. First, the sulfur-containing raw materials and nitrogen-containing reagents are condensed to construct the basic skeleton of benzothiazole. For example, when specific thiophenol derivatives and aminonitrile compounds are heated and reacted in an organic solvent under suitable basic conditions and catalysts, the benzothiazole ring system can be initially formed. Later, specific positions on the ring are modified to introduce propionylamino groups. Propionyl chloride or propionic anhydride can be reacted with the precursor by acylation reaction, and the introduction of 6-position propionyl amino group can be achieved under the appropriate alkali catalysis. At the same time, the reaction conditions, such as temperature, time, and the proportion of reactants, need to be precisely controlled in the reaction to ensure that the product configuration is (R) -type. This can be achieved by selecting a catalyst with chiral induction or using chiral auxiliary reagents.
Second, compounds with partial benzothiazole structure can also be used as starting materials. For example, benzothiazole derivatives containing appropriate substituents are synthesized first, and then the 4,5,6,7-tetrahydro structure is constructed by reduction reaction. A suitable reducing agent, such as lithium aluminum hydride or sodium borohydride, can be used to reduce the double bond of benzothiazole at low temperature and in an anhydrous environment. Then the amination and propionylamination steps are carried out, and the 2-amino and 6-propionylamino groups are introduced respectively. In the whole synthesis process, the reaction products in each step need to be strictly separated and purified, and column chromatography and recrystallization are often used to ensure the purity and configuration of the final product. In this way, the target product (R) - 2-amino-6-propionylamino-4,5,6,7-tetrahydrobenzothiazole can be obtained through the carefully designed and operated reaction in multiple steps.
(R) What are the application fields of -2-amino-6-propionamido-4, 5, 6, 7-tetrahydrobenzothiazole?
(R) -2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole has a wide range of application fields.
In the field of medicine, it is often the key raw material for creating new antibacterial drugs. The unique structure of the genome has specific antibacterial activities, and it may be effective against some drug-resistant strains, helping to overcome antibacterial problems and finding new treatment opportunities for patients.
In the field of pesticides, it also has its own uses. It can be exquisitely designed to prepare pesticides with high insecticidal and antibacterial properties. In this way, it can not only improve the yield of crops, but also ensure their quality, which is of great significance for agricultural development.
In the field of chemical materials, it may be an important monomer for the synthesis of special polymers. Through polymerization, polymer materials with special properties are generated, such as excellent heat resistance, chemical corrosion resistance and other characteristics, which are used in high-end fields such as aerospace and electronic devices.
Furthermore, in biological science research, (R) -2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole may be used as a biological probe to help researchers gain insight into the microscopic processes in living organisms, explore the mysteries of life, and promote cutting-edge research in biological science.
(R) What is the market outlook for -2-amino-6-propionamido-4, 5, 6, 7-tetrahydrobenzothiazole?
(R) -2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole. Although this substance has not been widely read in ancient books, it is gradually emerging in the field of medicine and chemical industry today, and the prospect is promising.
Looking at the market environment in which it is located, many signs show its potential. In the field of pharmaceutical research and development, it has attracted much attention as a key intermediate. At present, the conquest of various difficult diseases has prompted medical research to focus on new compounds. This compound has a unique structure or plays an important role in innovative drug synthesis. If a drug is developed for a specific target, it may be precisely embedded to help improve the efficacy of the drug, just like a tenon-mortise fit, a tight fit.
At the level of chemical production, demand is also on the rise. With the vigorous rise of the fine chemical industry, the demand for high-purity, special structural compounds is increasing. (R) -2 -Amino-6 -propionamido-4,5,6,7 -tetrahydrobenzothiazoline has its own characteristics and can participate in the preparation of a variety of high-end chemical products, such as high-performance material additives. The material properties are unique, like a good horse with a saddle, which complements each other.
However, its market road is not smooth. The synthesis process is complex and the cost remains high, such as boulders blocking the way, hindering the scale promotion. And market awareness is limited, many manufacturers are still waiting and seeing, and have not dared to set foot rashly. However, over time, if the process breaks through, the cost is controlled, and the awareness is gradually broadened, it will be like a flood dragon, revolutionizing the market and shining brightly, adding new brilliance to the industry and becoming a new engine for development.