What is the main use of the pharmaceutical intermediate 2-amino-1,3-thiazole-4-carboxylate ethyl ester (CAS number: 5398-36-7)?

2-Amino-1,3-propanediol-4-butyrate ethyl ester (CAS No.: 5398-36-7) is used in the field of pharmaceutical intermediates for critical purposes. It is mainly used in the synthesis of a variety of drugs and plays an indispensable role in the construction of medicinal chemistry.

In the creation process of cardiovascular drugs, this intermediate can be used as a key structural unit to participate in the construction of active molecules that regulate cardiovascular function. For example, some drugs for hypertension and arrhythmia are synthesized using 2-amino-1,3-propylene glycol-4-ethyl butyrate as one of the starting materials. Through a series of chemical reactions, a molecular structure with specific pharmacological activities is precisely built, and the purpose of treating diseases is achieved by interacting with relevant targets in the body.

In the research and development of neurological drugs, this intermediate also has important applications. It can be used as a key component in the synthesis of neurotransmitter regulators, nerve cell protective agents and other drugs. By modifying and derivatizing its chemical structure, drug molecules that can cross the blood-brain barrier and have high affinity and selectivity for specific targets in the nervous system can be prepared, providing an effective means for the treatment of nervous system diseases.

In addition, in the field of anti-infective drugs, 2-amino-1,3-propylene glycol-4-ethyl butyrate also plays an active role. It can participate in the synthesis of compounds with antibacterial and antiviral activities. After rational structural design and optimization, it has excellent antibacterial spectrum and pharmacokinetic properties, which can help fight various infectious diseases.

In summary, 2-amino-1,3-propylene glycol-4-butyrate ethyl ester, as a pharmaceutical intermediate, occupies a core position in the synthesis of many drugs due to its unique chemical structure, which is of great significance for promoting the progress of modern drug development and therapeutics.

What is the production process of pharmaceutical intermediate 2-amino-1,3-thiazole-4-carboxylate (CAS No.: 5398-36-7)

2-Amino-1,3-propylene glycol-4-carboxylic acid ethyl ester (CAS No.: 5398-36-7) is one of the pharmaceutical intermediates, and its preparation process is exquisite and complicated, which is quite the wonder of the ancient "Tiangong Kaifa".

To make this product, it is often used as a suitable starting material and follows a specific reaction path. First, a starting material is used to initiate the reaction under the environment of suitable temperature and pressure and a specific catalyst. This catalyst is like an ancient craftsman's tool to guide the direction of the reaction.

At the beginning of the reaction, the chemical bonds in the starting molecule are rewoven according to the laws of chemistry like silk threads. The atomic groups in the raw material, like chess pieces, are redistributed on the reaction "chessboard". After a delicate chemical change, key intermediate products are gradually generated.

This intermediate product is then finely processed, or extracted and separated, like the ancients sorting treasures, removing its impurities and leaving its essence. Then, under new reaction conditions, it reacts with others. The new reactants are like bricks and tiles, fused with the intermediate product, so that the molecular structure tends to the shape of the target product.

When the reaction is coming to an end, the crude product has been completed, but it still needs to be purified. Distillation, crystallization and other means can be used to make the product pure, just like carving jade into beautiful jade. In this way, the high purity of 2-amino-1,3-propylene glycol-4-carboxylic acid ethyl ester is obtained. The whole preparation process needs to be precisely controlled at every step. If there is a slight mistake, it is difficult to obtain a good product of this drug intermediate. It is a delicate interpretation of chemical technology and is also in line with the spirit of creation of "Tiangong Kaiwu".

What is the market price range for the pharmaceutical intermediate ethyl 2-amino-1,3-thiazole-4-carboxylate (CAS No.: 5398-36-7)?

I look at your question, and I am inquiring about the market price range of the pharmaceutical intermediate 2-hydroxy-1,3-dioxyamyl-4-ethyl acetate (CAS No.: 5398-36-7). However, the price of this pharmaceutical intermediate often changes due to various reasons, and it is difficult to be sure.

First, the price of raw materials has a great impact. If the raw materials required for its preparation fluctuate due to changes in weather, geographical location or supply and demand, the price of this intermediate will also fluctuate. Second, the market supply and demand trend is also the key. If there are many people in demand at a time, and the supply is insufficient, the price will rise; conversely, if the supply exceeds the demand, the price will decline. Third, the production process and cost also affect the price. The process is refined and the cost is low, or it can be sold at a lower price; if the process is complicated and the cost is high, the price will be higher.

In addition, the difference in region and quality can cause the price to vary. Roughly in the market, the price range of this intermediate, or due to the above factors, ranges from tens to hundreds of yuan per kilogram. However, this is only an approximate number. To know the exact price, it is necessary to study the market in detail and negotiate with various suppliers.

What are the Quality Standards for Pharmaceutical Intermediates Ethyl 2-Amino-1,3-thiazole-4-carboxylate (CAS No.: 5398 - 36 - 7)

2-Hydroxy-1,3-dioxyamyl-4-carboxylate ethyl ester (CAS No.: 5398-36-7) is a pharmaceutical intermediate, and its Quality Standard is very critical, which is related to the quality and safety of the drug. The following details of its Quality Standards:
First, in terms of appearance, it should be in the form of clear, no visible impurities, or white to off-white crystalline powder, or colorless transparent to slightly yellow clear liquid. This feature not only affects the appearance of the product, but also correlates with the purity. If there is obvious color or impurities, or suggests the presence of other substances mixed in.
Second, the purity requirements are extremely high, usually more than 98%, and even in some high-end use scenarios, the purity must exceed 99%. High purity is the basis for ensuring its accurate reaction in pharmaceutical synthesis and avoiding side reactions. Low purity is prone to fluctuations in drug quality and differences in efficacy.
Third, the melting point range is also an important indicator, generally with a specific melting point range, such as [specific melting point range]. This index can verify the purity and crystalline structure of the substance, deviate from the normal range, or indicate that the product is impure or has a change in crystal form.
Fourth, the limit of relevant substances is strictly limited, and the content of impurities generated during the synthesis process, such as starting materials, intermediates, by-products, etc., is strictly limited. For example, the specific impurity A should not exceed 0.1%, and the impurity B should not exceed 0.2%, in order to prevent the impurity from affecting the safety and effectiveness of the drug.
Fifth, the moisture content must be strictly controlled, usually less than 0.5%. Excessive moisture or affect the stability of the substance, trigger reactions such as hydrolysis, destroy the molecular structure, and reduce product quality.
Sixth, the heavy metal content must be extremely low, such as lead, mercury, cadmium and other heavy metals, the total amount shall not exceed 10 parts per million. Heavy metal residues will accumulate in the human body and endanger health, so drug-related intermediates strictly limit them.

What are the storage conditions for the pharmaceutical intermediate 2-amino-1,3-thiazole-4-carboxylate (CAS No.: 5398-36-7)?

2-Amino-1,3-propylene glycol-4-chloroacetate ethyl ester (CAS No.: 5398-36-7) is also a pharmaceutical intermediate. Its storage conditions are quite important.

This pharmaceutical intermediate should be stored in a cool and dry place. Cover a cool place to slow its changes due to heat and prevent its properties from changing. Dry places can protect it from moisture to prevent quality damage due to moisture disturbance. If it is in a humid place, or due to the action of water, hydrolysis and other reactions will damage its chemical structure and lose its effectiveness.

And it should be placed in a well-ventilated place. With good ventilation, the air can circulate, and volatile gases that may accumulate in the surrounding area can be removed to avoid excessive concentration caused by gas accumulation, which may cause safety risks, such as the risk of ignition and explosion.

Furthermore, keep away from fire and heat sources. This drug intermediate may be flammable or chemically unstable due to heat. In case of fire and heat source, it is easy to react violently and endanger safety.

It should also be stored separately from oxidants, acids, bases, etc. Due to its chemical properties, it is easy to react chemically when it encounters with them, causing them to deteriorate, or causing dangerous reactions.

In summary, 2-amino-1,3-propylene glycol-4-chloroacetate ethyl ester should be placed in a cool, dry, well-ventilated place, away from fire and heat sources, and separated from oxidants and other foreign substances to ensure its quality and safety.