Methyl Thiazole 5 Carboxylate
quinoline thiophene imidazole thiazole

Methyl thiazole-5-carboxylate

    Specifications

    HS Code

    898833

    Name Methyl thiazole-5-carboxylate
    Chemical Formula C5H5NO2S
    Molar Mass 143.16 g/mol
    Appearance Solid (usually)
    Color Off - white to pale yellow
    Odor Characteristic odor
    Melting Point 43 - 46 °C
    Boiling Point 105 - 107 °C at 12 mmHg
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
    Density 1.319 g/cm³
    Flash Point 102.7 °C

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    General Information
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    Frequently Asked Questions

    As a leading Methyl thiazole-5-carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of Methyl thiazole-5-carboxylate?
    Methylthiazole-5-carboxylic acid esters are widely used in various fields such as chemical industry and medicine.
    In the field of chemical industry, it is a key raw material for the synthesis of many fine chemicals. Due to its unique chemical structure, various compounds with special properties can be derived through various chemical reactions. For example, new organic materials containing thiazole rings can be formed by reacting with specific reagents. Such materials may have excellent stability, conductivity or optical properties, and have potential applications in electronic and optical materials.
    In the field of medicine, methylthiazole-5-carboxylate is also of great significance. It is often an important intermediate in the synthesis of drugs. The thiazole ring structure is common in many bioactive molecules. Drug molecules constructed on this basis may have biological activities such as antibacterial, anti-inflammatory, and anti-tumor. After modification and modification, the pharmacological properties of drugs can be optimized, and their efficacy and safety can be improved.
    In addition, in material science research, it may participate in the preparation of functional polymer materials. By means of copolymerization with polymer monomers, the materials are endowed with special chemical and physical properties, such as improving the solubility and mechanical properties of materials, providing new paths for the innovation and development of materials. From this point of view, methylthiazole-5-carboxylate has a wide range of uses in various fields and is an indispensable substance for promoting scientific and technological progress and industrial development.
    What are the physical properties of Methyl thiazole-5-carboxylate?
    Methylthiazole-5-carboxylic acid ester, this is one of the organic chemicals. It has some unique physical properties. Looking at its properties, under room temperature and pressure, it is mostly solid or liquid, and the color is colorless and transparent, or slightly yellowish, which varies depending on the purity and impurities contained.
    When talking about the melting point, it varies according to the specific structure and purity. Generally speaking, its melting point is often in a specific temperature range, which can be used as a reference for determining the purity in the process of organic synthesis. In terms of boiling point, due to the characteristics of intermolecular forces, the boiling point also has a corresponding range. A higher boiling point means that it is more difficult to evaporate in a heated environment, which is crucial in the separation and purification process.
    Solubility is also a key physical property. In organic solvents such as ethanol and ether, methylthiazole-5-carboxylic acid esters usually exhibit good solubility due to the principle of similar miscibility. However, in water, its solubility may be poor due to the difference in molecular polarity and water.
    In addition, density is also one of its characteristics. Relative density can reflect its comparison with water or other common substances. In chemical production and experimental operations, this property is related to practical applications such as mixing and delamination of substances.
    In summary, the physical properties of methylthiazole-5-carboxylic acid esters are diverse and complex, and they play an important role in many fields such as organic synthesis and drug development, helping researchers better control related chemical reactions and practical applications.
    What is the chemical synthesis method of Methyl thiazole-5-carboxylate?
    The synthesis of methylthiazole-5-carboxylic acid esters is an important issue in the field of organic synthesis. Its synthesis method depends on various organic reaction steps.
    First, suitable sulfur and nitrogen-containing compounds are often used as starting materials. For example, halogenated hydrocarbons with specific structures can be taken first and reacted with sulfur-containing nucleophiles to form the prototype of thiazole rings. In this reaction, the choice of halogenated hydrocarbons is very critical, and its structure and reactivity are related to the process of the subsequent reaction and the purity of the product.
    Then, through cyclization, the atoms in the molecule are rearranged and cycled to form a thiazole ring structure. This step requires precise control of the reaction conditions, such as temperature, solvent, catalyst, etc. Too high or too low temperature may lead to abnormal reaction rates and affect the yield of the product. The polarity and solubility of the solvent will also affect the stability of the intermediate and the reaction path of the reaction.
    After the thiazole ring is constructed, carboxyl esterification is performed to introduce methyl carboxylate groups. This reaction can be carried out under acid or base catalysis with suitable alcohols and carboxylic acids or their derivatives. Commonly used catalysts, such as concentrated sulfuric acid, p-toluenesulfonic acid, or basic catalysts such as pyridine and triethylamine, are selected according to the characteristics of the substrate.
    During the reaction process, each step needs to be carefully monitored and regulated. Thin-layer chromatography (TLC), nuclear magnetic resonance (NMR) and other analytical methods can be used to gain real-time insight into the reaction process and confirm the structure and purity of the product. And the products of each step of the reaction often need to be separated and purified, such as column chromatography, recrystallization, etc., to remove impurities and obtain pure methylthiazole-5-carboxylate. In this way, the target product can be obtained through multi-step reaction and fine operation.
    What is the price range of Methyl thiazole-5-carboxylate in the market?
    The price of methylthiazole-5-carboxylate in the market is difficult to determine for many reasons. This compound has different uses and is involved in various fields such as medicine, pesticides and materials. The demand of each field is different, resulting in different prices.
    The simplicity of its preparation process is also the influence of the price. If the preparation requires complicated processes, rare raw materials or harsh conditions, the price must be high; on the contrary, if the preparation is easier, the price may be slightly lower.
    And the market supply and demand situation has a huge impact on its price. If demand is strong but supply is small, the price will rise; if supply exceeds demand, the price will drop.
    And the products produced by different suppliers have different prices due to differences in quality. The superior price is high, and the second price is low.
    As far as I know, in the chemical raw material trading market, the price of methylthiazole-5-carboxylate may range from hundreds to thousands of yuan per kilogram. However, this is only an approximate number, and the market situation is changing rapidly. If you want to know the exact price, you need to consult each supplier in detail, and the current market price shall prevail.
    What are the storage conditions for Methyl thiazole-5-carboxylate?
    Methylthiazole-5-carboxylate is a fine chemical substance, and its storage conditions are crucial to the stability and quality of the substance.
    This substance should be stored in a cool, dry and well-ventilated place. Because of the cool environment, it can slow down the rate of chemical reactions that may occur. If the temperature is too high, it is easy to decompose or deteriorate. Dry conditions are also indispensable. If the ambient humidity is high, water vapor may interact with the substance, causing adverse reactions such as hydrolysis, which will damage its chemical structure and properties. Well-ventilated can disperse volatile gases that may accumulate in time to avoid excessive local concentrations and reduce potential safety risks.
    Furthermore, methylthiazole-5-carboxylate should be kept away from fires and heat sources. This substance may be flammable, and in case of open flames and hot topics, it may cause combustion or even explosion. And it needs to be stored separately from oxidizing agents, acids, bases, etc. Because of its active chemical properties, contact with the above substances, or cause violent chemical reactions, causing the substance to fail, and even lead to safety accidents.
    When storing, the container must be sealed. A good seal can prevent the intrusion of external air, moisture and other impurities, and maintain the purity and stability of the substance. Immediately after taking it, the container should be sealed as before to prevent the substance from being exposed to the air for a long time and being affected.
    In addition, the storage place should be regularly inspected to check whether the container is damaged or leaked. Once any abnormality is detected, timely measures must be taken to prevent material loss and environmental pollution. All these storage conditions are to ensure the quality and safety of methylthiazole-5-carboxylate, so that it can play its due role in subsequent applications.