Methyl 2 Amino 5 Iodo 1 3 Thiazole 4 Carboxylate
quinoline thiophene imidazole thiazole

methyl 2-amino-5-iodo-1,3-thiazole-4-carboxylate

    Specifications

    HS Code

    252914

    Chemical Formula C5H5IN2O2S
    Molar Mass 286.075 g/mol
    Appearance Solid (usually white to off - white powder)
    Melting Point Typically in a certain temperature range (specific value may vary based on purity)
    Solubility In Water Low solubility, sparingly soluble
    Solubility In Organic Solvents May be soluble in some polar organic solvents like DMSO, DMF
    Pka There is a characteristic pKa value related to the amino group
    Odor Odorless or very faint odor
    Stability Stable under normal conditions, but may decompose upon exposure to heat, light, or strong acids/bases
    Crystal Structure Has a defined crystal structure determined by X - ray diffraction techniques

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    General Information
    Where to Buy methyl 2-amino-5-iodo-1,3-thiazole-4-carboxylate in China?
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    Frequently Asked Questions

    As a leading methyl 2-amino-5-iodo-1,3-thiazole-4-carboxylate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of methyl 2-amino-5-iodo-1, 3-thiazole-4-carboxylate
    "Methyl + 2 - amino - 5 - iodo - 1,3 - thiazole - 4 - carboxylate" is the name of organic chemistry. Its chemical structure is described in the ancient style of "Tiangong Kaiwu", as follows:
    This compound is based on the thiazole ring. The thiazole ring is a five-membered heterocyclic ring containing sulfur and nitrogen. The sulfur and nitrogen atoms in the ring are arranged in phases, forming this unique structure. At the second position of the ring, the amino group and the amino group are connected by nitrogen and dihydrogen atoms, and are basic groups. At the fifth position of the ring, the iodine atom is connected, and the iodine atom has a large atomic radius and electronegativity. The fourth position of the ring is connected to the carboxylic acid methyl ester group. This group is connected by a carboxylic group and a methyl ester group. The carboxylic group is an acidic group containing carbon, oxygen and hydrogen. After being connected to the methyl ester group, the properties change.
    Looking at the whole, each group is connected to the thiazole ring in sequence, and affects each other to co-construct the unique chemical structure and properties of this compound. The spatial arrangement and electronic effects of each group affect the reactivity, physical properties and many other aspects of this compound.
    What are the main uses of methyl 2-amino-5-iodo-1, 3-thiazole-4-carboxylate
    Methyl-2-amino-5-iodine-1,3-thiazole-4-carboxylic acid ester, an organic compound. It is widely used in the field of medicinal chemistry and is often used as a key intermediate to assist in the synthesis of drug molecules with specific biological activities. For example, it may participate in the creation of antibacterial and antiviral drugs, and through structural modification and modification, it can endow drugs with better biological activity and pharmacokinetic properties.
    It also has potential applications in the field of materials science. Because it contains special thiazole rings and iodine atoms, it may participate in the preparation of materials with unique photoelectric properties, such as organic Light Emitting Diode (OLED) materials. The thiazole ring structure may improve the material stability and luminous efficiency, while the iodine atom can adjust the electron cloud distribution of the material and optimize the photoelectric properties.
    In the field of pesticide chemistry, it may also be used as a raw material for the synthesis of new pesticides. With its structural characteristics, pesticides that have high inhibition or killing effects on specific pests may be developed with low environmental impact, providing a green and efficient solution for agricultural pest control.
    What is the synthesis method of methyl 2-amino-5-iodo-1, 3-thiazole-4-carboxylate
    To prepare methyl 2-amino-5-iodine-1,3-thiazole-4-carboxylic acid ester, the following ancient methods can be used.
    First, appropriate starting materials are taken, and sulfur-containing compounds and nitrogen-containing compounds are used as groups. The two react together under suitable reaction conditions. A specific organic solvent is often used as the reaction medium to make the reactants well dispersed and contacted, and the solvent must be compatible with the reactants and products to avoid side reactions. The reaction temperature also needs to be precisely controlled, usually under moderate heating conditions, so that the reaction can proceed steadily. This temperature needs to be adjusted according to the characteristics of the reactants and the reaction mechanism, or between room temperature and tens of degrees Celsius.
    During the reaction process, it is necessary to pay attention to the progress of the reaction, which can be monitored by thin layer chromatography and other means. When the reaction reaches a specific level, the reactants are converted to the expected proportion, and subsequent treatment is carried out. Appropriate separation techniques, such as extraction, distillation, etc., separate the product from the reaction mixture to remove unreacted raw materials, by-products and solvents.
    When extracting, select a suitable extractant, which has good solubility to the product and is easy to stratify with other components of the reaction mixture. During distillation, the temperature is precisely controlled according to the difference between the boiling points of the product and impurities, so that the product can be purified and evaporated. Subsequent or recrystallization and other means to further purify the product to obtain high purity methyl 2-amino-5-iodine-1,3-thiazole-4-carboxylate. This ancient method requires careful control of the conditions of each step in order to make the product yield and purity good.
    What are the physical properties of methyl 2-amino-5-iodo-1, 3-thiazole-4-carboxylate
    Methyl 2-amino-5-iodine-1,3-thiazole-4-carboxylic acid ester, this is an organic compound, and its physical properties are worth exploring.
    Looking at its properties, under normal temperature and pressure, it is mostly solid, usually white to off-white crystalline powder, which is caused by the orderly arrangement of intermolecular forces. Its melting point is also an important characteristic, which is about a specific temperature range, but the exact value may vary due to factors such as purity. The determination of the melting point is like a delineation mark for its physical state transformation, which is of great significance for judging its existence and morphology under different conditions.
    In terms of solubility, in organic solvents, such as common methanol, ethanol, dichloromethane, etc., it exhibits a certain solubility. This is due to the principle of similar miscibility, and the molecular structure of the compound can form an appropriate force between the molecules of the organic solvent to promote dissolution. However, the solubility in water is poor, because the molecular polarity matches the polarity of the water molecule, it is difficult for the water molecule to effectively disperse the compound molecule.
    In addition, its density is also a key physical property. Although the exact density value needs to be determined by precise experiments, it can be roughly inferred that the density is within a certain range due to the molecular composition and spatial arrangement. The characteristics of density are related to its position in the mixed system and its interaction with other substances.
    Furthermore, the stability of this compound cannot be ignored. Under normal environmental conditions, it has a certain chemical stability. In case of extreme conditions such as high temperature, strong acid, and strong base, the molecular structure may be affected, triggering chemical reactions, causing it to decompose or transform into other substances. This stability property is a key consideration for ensuring the quality and efficacy of the compound when storing and using it.
    What is the price range of methyl 2-amino-5-iodo-1, 3-thiazole-4-carboxylate in the market?
    Methyl-2-amino-5-iodine-1,3-thiazole-4-carboxylic acid ester is in the market, what is the price? This is a specific compound of fine chemicals, and its price often changes due to multiple reasons.
    First look at the purity, high purity is expensive, if it reaches excellent purity, or several times more than ordinary industrial grade. According to the past market, high purity similar fine chemicals, or to tens of gold per gram, low purity or slightly cheaper.
    Second look at supply and demand, if the market demand is strong and the supply is low, the price will rise. If the demand for pharmaceutical research and development surges, the supply will be tight, and the price may rise sharply. In the past, the price of related intermediates has increased by several percent due to the research and development of certain new drugs.
    Furthermore, the production process also has an impact. If the process is complicated and the cost is high, the price is also expensive. Preparation of this compound, or involving multi-step reactions and special reagents, the cost increases and the price increases.
    The origin is different from the manufacturer, and the price is also different. Well-known large factories, due to excellent quality control, the price may be high; small factories are competitive, or slightly reduced. In the past, congeneric products were seen, and the price of large factories was higher than that of other factories.
    In general, the price per gram or a few gold to tens of gold ranges. The actual price should be consulted with the supplier in detail to obtain the exact number.